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This volume covers various assays and techniques that have been developed to study and characterize the cell migration in vitro, ex vivo, and in vivo. The chapters in this book present readers with the latest protocols to observe, quantify, and control cell migration. Some of the topics explored in this book are: migration in confined environments, microfluidic devices, optogenetics, chemotaxis, electrotaxis, detection of migrasomes, migration of Q cells in Caenorhabditis elegans, of Drosophila macrophages, optogenetics of cell migration, intravital imaging. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and comprehensive, Cell Migration: Methods and Protocols is a valuable resource for anyone interested in learning more about this expanding field.
This contributed volume provides a critical review of research in the field of Electrochemical Promotion of Catalysis (EPOC). It presents recent developments during the past decade that have led to a better understanding of the field and towards applications of the EPOC concept. The chapters focus on the implementation of EPOC for developing sinter-resistant catalysts, catalysts for hydrogen production, ammonia production and carbon dioxide valorization. The book also highlights the developments towards electropromoted dispersed catalysts and for self-sustained electrochemical promotion which are currently expanding. This authoritative analysis of EPOC is useful for various scientific communities working at the interface of heterogeneous catalysis, solid state electrochemistry and materials science. It is of particular interest to groups whose research focuses on developments towards a better and more sustainable future.
This volume comprises a collection of invited and selected contributions presented at the 16th International Conference on Laser Spectroscopy in Palm Cove, Queensland, Australia, 13-18 July 2003. The papers report the latest and most exciting developments in laser spectroscopy and related areas: new ultra-precise spectroscopic measurements based on optical frequency combs including tests of the stability of the fundamental constants; the first realization of Bose-Einstein condensation in cesium and ytterbium; the behavior of ultra-cold bosons and fermions in optical lattices; the production of ultra-cold cesium, helium and fermionic lithium molecules; the production and coherent transport of ultra-cold atoms in microtraps on the surface of chips; the implementation of one- and two-qubit quantum algorithms and experiments towards a scalable quantum computer based on trapped ions; and new medical applications of laser spectroscopy.The proceedings have been selected for coverage in: ? Index to Scientific & Technical Proceedings? (ISTP? / ISI Proceedings)? Index to Scientific & Technical Proceedings (ISTP CDROM version / ISI Proceedings)? CC Proceedings ? Engineering & Physical Science
This volume comprises a collection of invited and selected contributions presented at the 16th International Conference on Laser Spectroscopy in Palm Cove, Queensland, Australia, 13-18 July 2003. The papers report the latest and most exciting developments in laser spectroscopy and related areas: new ultra-precise spectroscopic measurements based on optical frequency combs including tests of the stability of the fundamental constants; the first realization of Bose-Einstein condensation in cesium and ytterbium; the behavior of ultra-cold bosons and fermions in optical lattices; the production of ultra-cold cesium, helium and fermionic lithium molecules; the production and coherent transport of...
Many cells, including immune, neuronal, cancer and stem cells, become dependent on aerobic glycolysis to escape apoptosis and accommodate their bioenergetics needs. How this metabolic change, also known as the Warburg effect, is regulated remains largely unknown. The Warburg effect has been widely investigated in cancer cells where it was first observed with the aim of decoding the molecular networks controlling its activation for therapeutic purposes. This Research Topic aimed to discuss and review all the intracellular signaling regulating the Warburg effect in cancerous and normal non-cancerous cells though original research articles, mini reviews and reviews.
Bone metastases are common in many cancers and associated with skeletal-related events such as spinal cord compression, fractures, pain, disability, and impaired quality of life. Bone metastasis is most prominent in breast, prostate, and lung cancer patients and is the leading cause of cancer-associated death. Osteoblasts and osteoclasts control each other’s functions to maintain normal bone homeostasis. In addition, bone remodeling is governed by the balanced activity of the bone and immune cells. Bone metastasis is a multistage process, and the bone microenvironment influences the seeding and colonization of the disseminated cancer cells. Disruption of bone homeostasis and immune population provides fertile soil to facilitate cancer cell seeding. Despite the advancement of our understanding to treat primary tumors, most of the treatments for bone metastasis are palliative. Proper understanding of the immune component of the bone and their involvement in bone metastasis niche formation will help to explore future directions of bone metastasis research.