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Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy (DMD) is one of the most prevalent genetic disorders of childhood and currently stands as an incurable condition. This authoritative guide provides a clear overview of the latest current and experimental approaches to the treatment of DMD and examines the clinical, genetic, and pathophysiological aspects of the disease i
Cardiac Development
The importance of the developmental approach for experimental and clinical cardiology is indisputable. Clinical-epidemiological studies have clearly shown that the risk factors of serious cardiovascular diseases, such as atherosclerosis and ischemic heart disease, are already present during the early phases of ontogenetic development. Furthermore, congenital cardiovascular malformations remain the single largest cause of infant mortality from congenital defects in industrial countries. It is therefore not surprising that the interest of theoretical and clinical cardiologists in the developmental approach keeps increasing. Advances in molecular biology accelerated this trend substantially. Th...
Biological Sciences and Environmental Health
The book captures the essence of the First International Conference on Frontiers of Biological Sciences and Environmental Health (FBSEH 2023). It provides a comprehensive roadmap to achieving sovereignty, security and safety of human health by adopting a multi-disciplinary approach to disease diagnosis, mitigation and prevention. These proceedings contains a repository of unique ideas, cutting edge research methodologies and exhaustive studies by experts, scholars from all over the world. It touches upon a wide array of topics including advances in bioengineering and genetic technologies, nutrition and disease prevention, emerging therapeutic strategies and drug delivery, along with the advent of microfluidics, wearables, and medical devices. It highlights innovative research contributions and practical applications that would prove critical in fighting cancer and genetic disorders in the future. This is a highly beneficial guide to university professors, research scholars and medical professionals in the rapidly evolving fields such as microbiology, biotechnology, biomedical engineering, molecular medicine, public health and community medicine, and healthcare sciences.
Inflammation and Cardiac Diseases
Heart failure research is a most active area of research in academic, industrial and government-sponsored research and receives intense clinical attention. The recent recognition that inflammation is a risk factor and prognostic factor for heart disease has laid ground for preventive medicine and even anti-infective strategies in prevention and treatment of heart failure. Provides a new perspective on the etiology of cardiac failure Covers the latest developments Discusses future treatments for heart failure Ideal for researchers and clinicians
Epigenetics and Biological Processes
Epigenetics and Biological Processes deals with epigenetic control of various plant processes such as chromatin modification, biomacromolecule interactions, cell cycle, DNA replication, DNA recombination, DNA damage response, transcription, RNA processing and translation initiation, host restriction and modification, heterochromatin, euchromatin, centromere functions, telomeric maintenance, transposon activation, transposon silencing, transposon reactivation, photosynthesis, respiration, transpiration, polyploidisation, heterosis, homeostasis, cytoplasmic male sterility, self-incompatibility, circadian clocks, epigenetic imprinting, dosage compensation, somaclonal variation, plant stress res...
Molecular Marker Techniques
This edited book covers the applications of molecular markers in the genetic improvement of crop plants. Recent advances in molecular marker techniques such as the development of high-throughput genotyping platforms, marker-assisted selection, and non-coding RNA-based markers have been discussed. Essential information is provided on functional markers, genotype-by-sequencing, and association mapping methodologies that can facilitate accelerated crop breeding programs for increased yield, high nutritional quality, and tolerance to a variety of abiotic and biotic stresses. This volume presents basic information on molecular marker techniques from marker location up to gene cloning. The book includes a description of technical approaches in genome analysis such as comparison of marker systems, positional cloning, and array techniques. This book is of interest to teachers, researchers, and plant breeders. The book also serves as additional reading material for undergraduate and graduate students of agriculture, horticulture, and forestry.
Revolutions in Human Biospecimen Study: Leveraging new technologies to explore the pathology, therapeutics and biomarkers for atherosclerotic disease
Over the last few years, new high-throughput biotechnologies are revolutionizing our ways to utilize human biospecimens for understanding atherosclerotic disease. These recent advances allow deep profiling of individual cells at the genomics, epigenomics, transcriptomics and proteomics levels, or even simultaneous detection of various combinations of ‘Omics’ in the same cell. Additionally, novel methods to integrate data at different levels from tissue sections and dissociated tissues are the emerging trends in large and institutional biobank studies. Growing literature has shown the value of such sequencing and bioinformatic strategies in shedding light on (1) how risk genes, as identified by the Genome-Wide Association Study, contribute to atherogenesis (genotype to phenotype), and (2) how features of atherosclerotic lesions affect patient response in clinical trials (phenotype to the clinical outcome). The hybrid of cutting-edge biotechnologies and bioinformatic approaches helps us maximize biobank resources to accelerate bench-to-bedside research.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Ion Channels of Nociception
The Special Issue “Ion Channels of Nociception” contains 13 articles united by a focus on the peripheral mechanisms of pain. The content covers the mechanisms of neuropathic, inflammatory, and dental pain as well as pain in migraine and diabetes; nociceptive roles of P2X3, ASIC, Piezo and TRP channels; pain control through GPCRs and pharmacological agents; and nonpharmacological treatment with electroacupuncture.
