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“Role of selenium in health and disease”. This book contains ten articles covering recent advances in our understanding of the relationship between the essential micronutrient selenium and human health and disease. Taken together, these articles strengthen the evidence showing that selenium, as a constituent of selenoproteins, is central to biological stress responses and mechanisms commonly altered in most complex disorders. Relevant to public health concerns, this book also emphasizes the U-shaped dose-response relationship between selenium concentration and disease risk across diverse populations from Europe [articles 2,3,6], the Middle East and North Africa [9], and Taiwan [5]. This ...
Many health benefits have been attributed to selenium that include preventing various forms of cancer (e.g., colon cancer, prostate cancer, lung cancer and liver cancer), heart disease and other cardiovascular and muscle disorders, inhibiting viral expression, delaying the progression of acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus (HIV)-positive patients, slowing the aging process, and having roles in mammalian development, including male reproduction and immune function. The purpose of the book is the same as the first two volumes which is to bring an up to date status of current research in the rapidly developing selenium field centered around the health benefits attributed to this element and how this element makes its way into protein.
This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more. A special focus will be placed on in-depth knowledge about gene expression, selenoprotein biosynthesis, seleno-metabolism--as well as the molecular pathways, physiological roles, and the molecular action of selenium including interaction with other elements and vitamins or as Se-nanoparticles. The reader will receive the newest information regarding redox status and redox regulatory systems, specifically in relation to different glutathione peroxidases and thioredoxin-reductases as well as about cellular bioavailability and cytotoxicity, de-balanced immune response, inflammation or dietary aspects.
Die zunehmende klinische Bedeutung der essentiellen Spurenelemente und Mineralstoffe war Gegenstand der 23. Tagung der Gesellschaft für Mineralstoffe und Spurenelemente e.V. in Stuttgart. Neben den Spurenelementen Antimon, Jod und Cadmium lag der Schwerpunkt auf Selen. Die Ergebnisse klinischer Studien zeigen die Anwendbarkeit zur Mortalitätsreduktion bei Sepsis, zur Reduktion von Nebenwirkungen der Strahlentherapie von Patienten mit Cervix- oder Corpus uteri-Karzinomen, zur Abnahme von Autoimmunantikörpern und Verbesserung klinischer Beschwerden bei entzündlichen Autoimmunkrankheiten der Schilddrüse wie Hashimoto- Thyreoiditis, zum Rückgang des Weichteilödems bei Patienten mit postradiogenen oder postoperativen Ödemen im Bereich der Mundhöhle. Ein lesenswertes wissenschaftliches update der Mineralstoffe und Spurenelemente, das sich durch die große Zahl der Beiträge unterschiedlicher Autoren durch Lebendigkeit und Vielfalt auszeichnet.
This book covers many facets of plant selenium (Se) accumulation: molecular genetics, biochemistry, physiology, and ecological and evolutionary aspects. Broader impacts and applications of plant Se accumulation also receive attention. Plant Se accumulation is very relevant for environmental and human health. Selenium is both essential at low levels and toxic at high levels, and both Se deficiency and toxicity are problems worldwide. Selenium can positively affect crop productivity and nutritional value. Plants may also be used to clean up excess environmental Se. Selenium in plants has profound ecological impact, and likely contributes to Se movement in ecosystems and global Se cycling.
Handbook of Proteolytic Enzymes, Second Edition, Volume 1: Aspartic and Metallo Peptidases is a compilation of numerous progressive research studies on proteolytic enzymes. This edition is organized into two main sections encompassing 328 chapters. This handbook is organized around a system for the classification of peptidases, which is a hierarchical one built on the concepts of catalytic type, clan, family and peptidase. The concept of catalytic type of a peptidase depends upon the chemical nature of the groups responsible for catalysis. The recognized catalytic types are aspartic, cysteine, metallo, serine, threonine, and the unclassified enzymes, while clans and families are groups of homologous peptidases. Homology at the level of a family of peptidases is shown by statistically significant relationship in amino acid sequence to a representative member called the type example, or to another member of the family that has already been shown to be related to the type example. Each chapter discusses the history, activity, specificity, structural chemistry, preparation, and biological aspects of the enzyme. This book will prove useful to enzyme chemists and researchers.
This book is a printed edition of the Special Issue "Nutrients, Infectious and Inflammatory Diseases" that was published in Nutrients
Selenium is arguably the naturally occurring trace element of greatest concern worldwide. In excessive amounts it can lead to toxicosis and teratogenesis in animals, while the impact of selenium deficiency can be even more significant. Contributors from 22 countries explored the connections and inter-relationships between selenium in the environmen
Ditch diet culture and get the most nutrients from your food with the no-guilt, personalized, and exciting new science that will change how you think about food and nourishment, from New York Times bestselling author Dr. Sarah Ballantyne. Almost all of us are missing essential vitamins and minerals from our diets that leave us feeling unwell and unable to achieve our health goals—even those of us who take our daily multi, buy organic produce, or have tried to kick-start our health with different dietary habits. Now, bestselling author Dr. Sarah Ballantyne throws all of that out the window in favor of a simple yet radical idea: choose foods to meet our nutritional needs. Unlock health and v...