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An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
This book presents the principles and the tools for participatory evaluation of sustainable development--growth that does not compromise the ability of future generations to meet their needs. It is intended for any citizen or group that may be concerned with protecting or recovering a cultural heritage, assessing the impact of a project or of plans that impact an environment or ecosystem.The authors describe participatory evaluation processes that will empower all interested "stakeholders"--anyone impacted by a proposed venture--to determine and control what is to be evaluated and how it is evaluated, to articulate and define their community’s vision, and to ensure that development plans m...
Environmental policy domains are increasingly adopting strategies of cooperation over those of conflict. Decision-making processes founded upon collaboration and public participation are receiving more attention and favor and, in turn, engendering multistakeholder environmental partnerships. In his thoughtful analysis, Eric C. Poncelet seeks to illuminate the mechanics of these partnerships, especially at the level of social interaction. Drawing on ethnographic research performed with four case study partnerships in the European Union and the United States, Poncelet focuses on the diverging ways that stakeholders think, talk, and conventionally act with regard to the environmental issues at stake. Also explored are the roles of environmental partnerships as sites of personal transformation, where participants_and their perspectives, conceptualizations, and expectations_can and do change. Partnering for the Environment concludes by examining the broader implications of multistakeholder partnerships for the future of environmental decision-making and suggests ways by which these partnerships may be more effectively used and managed.
Molecular Genetics of Inherited Eye Disorders provides an authoritative and up-to-date account of molecular genetic advances in a wide spectrum of genetic eye disorders, and forms the second volume in the Modern Genetics book series. The field has produced some dramatic and often unexpected findings in recent years ranging from the elegant unravelling of the molecular basis of colour vision defects to the subtle complexity of the retinoblastoma gene. The role of crystallins in congenital cataract and of the rhodopsin molecule in retinitis pigmentosa are discussed, illustrating the importance of the candidate gene approach to genetic eye disease. Reverse genetic approaches to the cloning of genes responsible for aniridia and choroideremia exemplify the power of the new genetic techniques and signal the start of the next experimental phase, in which the functional characterization of identified genes begins.
'The book is well-written and makes a significant contribution to the development of the principles and practices of dealing with agri-environmental problems. It is of relevance to a wide circle of readers, including researchers and politicians but also students and others concerned with agri-environmental issues.' - Stefanie Engel and Ulrike Grote, Quarterly Journal of International Agriculture '. . . the book has the potential to provide something for everyone.' - Stefan Bäckmann, European Review of Agricultural Economics Although the history of the Common Agricultural Policy (CAP) is dominated by a process of centralisation, growing pressures to integrate agri-environmental problems into the CAP have revealed the need to embrace decentralised approaches in an efficient federal structure. Indeed, in recent years it has become increasingly evident that the agricultural sector must undergo fundamental changes in order to enter an era of sustainable development.
This volume presents a state-of-the-art overview of the rapidly evolving field of agribusiness, highlighting the most current issues, concepts, trends and themes in research, practice and policy. With a particular emphasis on technology, product and process innovation, the authors cover a wide array of topics relating to such issues as research and development, technology transfer and patents and licensing, with particular respect to the roles of academic institutions, private organizations and public agencies in generating and disseminating knowledge. Featuring case studies of innovative initiatives across the industry, this book will appeal to researchers, business leaders, university administrators and policymakers concerned with the multi-faceted implications of this dynamic and controversial sector.
This book provides comprehensive coverage of the most important corneal diseases in children, including congenital corneal opacities, infectious keratitis, corneal ectasia, ocular surface disorders and allergic eye disease. Highlights include an extensive discussion of corneal surgery in children, in-depth coverage of the role of various anterior segment ocular imaging modalities in the diagnosis and management of corneal diseases in the pediatric population, and surgical videos to further assist the reader. Chapters dedicated to amblyopia management and contact lens use in children round out the volume. Corneal Diseases in Children stands out as one of the few books dedicated to this important topic.
As health systems all over the world not only recover from COVID-19, but learn to adapt to contexts of increasing uncertainty amidst persistent challenges, it is clear that systems thinking has never been needed more. Systems thinking is an approach to problem-solving that views problems as part of a wider dynamic system. It recognizes and prioritizes the understanding of linkages, relationships, interactions and interdependencies among the components of a system that give rise to the system’s observed behaviour. Systems thinking is a philosophical frame, and it can also be considered a method with its own tools. Identifying ways in the short and long-term which strengthen health systems i...