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This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care. The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel approach for treating peritoneal carcinomatosis. First encouraging results have been obtained in human patients.
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Peritoneal dissemination is a common route of cancer metastasis. The benefit of administering chemotherapy directly into the peritoneal cavity is supported by preclinical and pharmacokinetic data. In comparison to intravenous (IV) treatment, intraperitoneal (IP) administration results in a several-fold increase in drug concentration within the abdominal cavity. There is now growing evidence from clinical studies showing a survival advantage for IP chemotherapy in various tumor typies, including ovarian, gastric and colorectal cancer. However, while the use of IP chemotherapy is slowly gaining acceptance, it is not universal, largely due to the greater toxicity associated with this approach. ...
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel approach for treating peritoneal carcinomatosis. First encouraging results have been obtained in human patients.
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Now updated online for the life of the edition, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 11th Edition keeps you up to date in this fast-changing field. Every quarter, your eBook will be updated with late-breaking developments in oncology, including new drugs, clinical trials, and more.
The extraordinary tapestry of Cairo's past and present comes vividly to life in this magisterial study by one of the top social historians of the Arab world. This deeply observed account shows Cairo from the glimmer of its beginnings in the Arab conquest of Egypt in 640 through its transformation into the modern center of Middle Eastern life today. 63 halftones. Maps & tables.
La Bible est une formidable bibliothèque généraliste. Elle accueille un corps de littératures très diversifié quant à son extension dans la durée et quant au genre de textes qu'elle donne à lire. Bien plus, la Bible restitue au lecteur des écrits qui n'y figurent parfois pas explicitement, mais qui ont baigné les auteurs jusqu'à ressortir quasi intacts dans les textes canoniques. Tout texte appelle donc à la mémoire du lecteur d'autres textes, et, dans la Bible, leur identification reste pour l'heure relativement difficile à effectuer. L'exégèse traditionnelle a jusqu'ici peu exploité l'approche intertextuelle. Les auteurs de cet ouvrage ont l'ambition de fournir et d'illus...