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The book that the reader has in his hands was written in the Spanish that was used in the northwest of the Iberian Peninsula half a millennium ago, which no international magazine in which I publish my articles arising from my research in my Cinvestav laboratory would accept the title "the first three deaths of Marcelino Cereijido".
In response to the tremendous increase in the number of protein and peptide drugs, this treatise critically reviews transport and metabolism mechanisms relating to the delivery of endogenous and recombinant proteins to mammalian organs, tissues, and cells. It will promote fruitful collaboration among academic and industrial scientists in the fields of pharmacology, cell biology, biochemistry, physiology, and immunology.
As the first detailed overview of the subject, Tight Junctions brought together diverse perspectives from leading investigators to provide a multidisciplinary overview of the field. Since its publication in 1992, there has been an explosion of information about tight junctions, particularly in the area of molecular structure, cell and molecular bio
Miguel Arenas Vargas, creador del método educativo que lleva su nombre, nació en la ciudad de México, Distrito Federal, el 14 de julio de 1940. Ha dedicado su vida a la formación de científicos independientes en pequeñas comunidades esparcidas en la periferia de la república mexicana a partir del reconocimiento que la sociedad mexicana, así como la de muchos países con economías en desarrollo necesitan de científicos para poder acceder a mejores condiciones de vida para sus habitantes. Al tratar de responder la pregunta: ¿Cómo aprende el hombre?, propone una revolución en la educación para la salud humana, la salud animal y el aprovechamiento de los recursos naturales, mediant...
Cellular domains play vital roles in a wide range of cellular functions. Defining cellular domains and understanding the molecular basis of their formation is essential to the study of cell functionality. This authoritative reference provides the most comprehensive analysis available on cellular domains, with emphasis on the definition and molecular composition of the domain as well as the functional implications of domain organization.
Biological Horizons in Surface Science presents techniques used in surface science research as well as experimental data. It is organized in such a way that there is a transition from the more theoretical or molecular to the more biological. Emphasis is placed on the importance of water in determining molecular architecture and interactions. Methods of examining molecular associations and complex formation of molecules are discussed, and the results from such studies are reviewed. Permeability is examined from the point of view of the energies required to penetrate between two different phases, and from the role that multicellular membranes may play in directing the diffusion of ions or solu...
Science and Catholicism in Argentina (1750–1960) is the first comprehensive study on the relationship between science and religion in a Spanish-speaking country with a Catholic majority and a "Latin" pattern of secularisation. The text takes the reader from Jesuit missionary science in colonial times, through the conflict-ridden 19th century, to the Catholic revival of the 1930s in Argentina. The diverse interactions between science and religion revealed in this analysis can be organised in terms of their dynamic of secularisation. The indissoluble identification of science and the secular, which operated at rhetorical and institutional levels among the liberal elite and the socialists in the 19th century, lost part of its force with the emergence of Catholic scientists in the course of the 20th century. In agreement with current views that deny science the role as the driving force of secularisation, this historical study concludes that it was the process of secularisation that shaped the interplay between religion and science, not the other way around.
This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals of epithelial transport; mathematical modeling of ion transport; cell volume regulation; membrane protein folding and trafficking; transepithelial transport functions; and lastly, a discussion of transport proteins as potential pharmacological targets with a focus on the pharmacology of potassium channels.
This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their responsibility in maintaining homeostasis. The reader gains an understanding of the fundamentals of epithelial ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the third of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology o...
Human physiology is the scientific exploration of the various functions (physical, biochemical, and mechanical properties) of the human body, its organs, and its component cells. The endocrine and nervous systems play an important role in maintaining homeostasis in the human body. This book focuses on stroke-induced muscle atrophy, lung disease, and myocardial glycation, dealing respectively with their mechanisms, altered immune responses, and effects on epithelial cell physiology. Gut bacteria form a complex ecosystem through metabolite exchange with the host and are deeply involved in the pathogenesis of diseases (obesity, diabetes, cancer). The book also discusses research trends in gut bacteria and how to diagnose patients with amyloidosis. It will be of interest to professionals involved in clinical practice, as well as to medical and healthcare students and even researchers involved in human physiology.