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Quantitative Biosciences Companion in R
A hands-on lab guide in the R programming language that enables students in the life sciences to reason quantitatively about living systems across scales This lab guide accompanies the textbook Quantitative Biosciences, providing students with the skills they need to translate biological principles and mathematical concepts into computational models of living systems. This hands-on guide uses a case study approach organized around central questions in the life sciences, introducing landmark advances in the field while teaching students—whether from the life sciences, physics, computational sciences, engineering, or mathematics—how to reason quantitatively in the face of uncertainty. Draw...
Quantitative Biosciences
A hands-on approach to quantitative reasoning in the life sciences Quantitative Biosciences establishes the quantitative principles of how living systems work across scales, drawing on classic and modern discoveries to present a case study approach that links mechanisms, models, and measurements. Each case study is organized around a central question in the life sciences: Are mutations dependent on selection? How do cells respond to fluctuating signals in the environment? How do organisms move in flocks given local sensing? How does the size of an epidemic depend on its initial speed of spread? Each question provides the basis for introducing landmark advances in the life sciences while teac...
Asymptomatic
The riveting account of how asymptomatic transmission drove COVID-19's global spread and catalyzed interventions to control it. Why was COVID-19 so difficult to contain and so devastating to people and economies worldwide? In Asymptomatic, author Joshua S. Weitz explains how silent transmission enabled COVID-19's massive and tragic global impact. Weaving the science of viral infections together with an insider's look at response efforts, Weitz guides readers through the shockwaves of successive epidemic waves as public health officials and academic research teams confronted the rise and risk of what was then a burgeoning global pandemic. The discovery of asymptomatic spread also fueled compe...
Nano Comes to Life
"Increasingly, scientists are gaining control over matter at the nanometer scale. Spearheaded by physical scientists operating at the interfaces of physics and biology (such as the author herself), advances in nanoscience and technology are transforming how we think about life and treat human health. This is due to a convergence of size. To do medicine, one must understand and be able to reach the nanoscale environment of healthy cells in tissues and organs, as well as other nano-sized building blocks that constitute a living organism, such as proteins and DNA. The ground-breaking advances being made at the frontiers of nanoscience and -technology, specifically in the areas of biology and me...
So Simple a Beginning
A biophysicist reveals the hidden unity behind nature’s breathtaking complexity The form and function of a sprinting cheetah are quite unlike those of a rooted tree. A human being is very different from a bacterium or a zebra. The living world is a realm of dazzling variety, yet a shared set of physical principles shapes the forms and behaviors of every creature in it. So Simple a Beginning shows how the emerging new science of biophysics is transforming our understanding of life on Earth and enabling potentially lifesaving but controversial technologies such as gene editing, artificial organ growth, and ecosystem engineering. Raghuveer Parthasarathy explains how four basic principles—se...
Molecular Machines
Molecular Machines presents a dynamic new approach to the physics of enzymes and DNA from the perspective of materials science. Unified around the concept of molecular deformability—how proteins and DNA stretch, fold, and change shape—this book describes the complex molecules of life from the innovative perspective of materials properties and dynamics, in contrast to structural or purely chemical approaches. It covers a wealth of topics, including nonlinear deformability of enzymes and DNA; the chemo-dynamic cycle of enzymes; supra-molecular constructions with internal stress; nano-rheology and viscoelasticity; and chemical kinetics, Brownian motion, and barrier crossing. Essential readi...
Kinetics of Heterogeneous Catalytic Reactions
This book is a critical account of the principles of the kinetics of heterogeneous catalytic reactions in the light of recent developments in surface science and catalysis science. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
The Molecular Switch
A signature feature of living organisms is their ability to carry out purposeful actions by taking stock of the world around them. To that end, cells have an arsenal of signaling molecules linked together in signaling pathways, which switch between inactive and active conformations. The Molecular Switch articulates a biophysical perspective on signaling, showing how allostery—a powerful explanation of how molecules function across all biological domains—can be reformulated using equilibrium statistical mechanics, applied to diverse biological systems exhibiting switching behaviors, and successfully unify seemingly unrelated phenomena. Rob Phillips weaves together allostery and statistica...
On the Future
A provocative and inspiring look at the future of humanity and science from world-renowned scientist and bestselling author Martin Rees Humanity has reached a critical moment. Our world is unsettled and rapidly changing, and we face existential risks over the next century. Various outcomes—good and bad—are possible. Yet our approach to the future is characterized by short-term thinking, polarizing debates, alarmist rhetoric, and pessimism. In this short, exhilarating book, renowned scientist and bestselling author Martin Rees argues that humanity’s prospects depend on our taking a very different approach to planning for tomorrow. The future of humanity is bound to the future of science...
Life on Land
The problems related to the process of industrialisation such as biodiversity depletion, climate change and a worsening of health and living conditions, especially but not only in developing countries, intensify. Therefore, there is an increasing need to search for integrated solutions to make development more sustainable. The United Nations has acknowledged the problem and approved the “2030 Agenda for Sustainable Development”. On 1st January 2016, the 17 Sustainable Development Goals (SDGs) of the Agenda officially came into force. These goals cover the three dimensions of sustainable development: economic growth, social inclusion and environmental protection. The Encyclopedia of the U...
