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Endosomes
Endosomes are a heterogeneous population of endocytic vesicles and tubules that have captivated the interest of biologists for many years, partly due to their important cellular functions and partly due to their intriguing nature and dynamics. Endosomes represent a fascinating interconnected network of thousands of vesicles that transport various cargoes, mainly proteins and lipids, to distant cellular destinations. How endosomes function, what co-ordinates the molecular determinants at each step of their dynamic life cycle and what their biological and medical relevance is, are among the questions addressed in this book.
Narrative Elements in the Double Tradition
For a long time mainstream gospel scholarship has assumed that the so-called Q material (the "double tradition") in Matthew and Luke represents a document or tradition that was almost exclusively orientated towards the sayings of Jesus of Nazareth, with little interest in a narrative about him. This book argues, on the contrary, that the narrative material in the double tradition existed from the very beginning within a coherent Jesus narrative that ran from his baptism to his passion. Far from being inserted by Matthew and Luke into the framework of Mark, the double tradition is structured on the very same narrative framework as the Gospel of Mark (a framework that predates Mark). Conventional dichotomies in gospel origins, the historical Jesus, and the history of early Christianity are thus drawn into question.
Membrane Trafficking in Viral Replication
Viruses are major pathogens in humans, and in the organisms with which we share this planet. The massive health and economic burden these agents impose has spurred a huge research effort to understand their most intimate details. One outcome of this effort has been the production, in many but certainly not all cases, of effective vaccines and therapies. - other consequence has been the realization that we can exploit viruses and put them to work on our behalf. Viruses are still seen to have the most - tential as vehicles for gene delivery and other therapeutic applications. However, their ability to exploit cellular functions to their own ends makes viruses not only highly effective pathogens but also exquisite experimental tools. Work with viruses underpins much of our current understanding of molecular cell biology and related fields. For membrane traffic in parti- lar, viruses have been crucial in providing insights into key cellular fu- tions and the molecular mechanisms underlying these events.
The Ironmonger
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Poems for You about Me, My Friends and Our Emotions
How does one summarize an eclectic collection of words that express the jumbled sets of complex emotions spanning a lifetime? What they mean to those who were the motivation for their creation cannot begin to be expressed to "mere" readers who happen upon this book as passersby to a recent accident. You see the results, but needed to have been there to fully feel the impact on your emotions. Yet poetry, like art of a more physical nature, has meaning to each of us on our own level. It is with that thought in mind that the author submits these poems to the world. If nothing is gained from the reading, but a single laugh; a solitary tear, or one knowing nod of the head; then the job will have been worth the doing. Please walk the path of life a little less quickly and hug those you love a bit more often.
