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This volume provides a detailed and comprehensive review of current knowledge concerning all aspects of gastroesophageal reflux disease (GERD). The opening chapters on its pathogenesis and epidemiology include discussions of Helicobacter pylori as an etiological agent, and Barrett's esophagus. The bulk of the volume is taken up with critical reviews of all the contemporary approaches to GERD - both medical and surgical (open and laparoscopic) - and presents the early results from laparoscopic trials throughout the world. The book concludes with detailed descriptions from expert practitioners of the various alternative laparoscopic fundoplication techniques. This timely publication will be of interest not only to gastroenterologists and gastrointestinal surgeons, but to all doctors and general practitioners who must advise and prescribe treatment for patients with this common, distressing, but remediable complaint.
A variety of new cancer therapy modalities are discussed and evaluated in this book. It aims to demonstrate that the combination of classical chemo- and radiotherapy with new approaches in the field of immunotherapy can result in an improved treatment modality. Immunotherapy in this context consists of therapy with monoclonal antibodies, hematopoietic growth factors and other lymphokines. Results of early clinical trials with IL-2, GM-CSF and monoclonal antibodies against gastrointestinal tumors and melanoma are included. The progress in regional chemotherapy strategies, for example of the liver, is shown. In addition, the development of new chemotherapeutic agents with a different mode of action as well as better tolerability is presented. The use of hormones, such as LH-RH agonists, allows hormone-dependent tumors such as prostatic and breast cancer to be treated without strong adverse reactions. These recent findings give the reader insight into exciting therapeutic directions made possible by such combined, rather than single, modalities.
Comprehensive and complete, Blumgart’s Surgery of the Liver, Pancreas and Biliary Tract – edited by Dr. William R. Jarnagin and a team of experts- delivers the comprehensive, cutting-edge guidance you need to achieve optimal outcomes in surgery of the liver, biliary tract, and pancreas. Edited by a panel of experts and featuring contributions by many leading authorities, this 2-volume reference brings you the latest information on pathology, diagnostics, surgery, and non-operative intervention all in one source. At www.expertconsult.com you can not only access the complete contents online, but also an abundance of detailed illustrations and step-by-step procedural video clips from the Me...
Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.
Never before has a comprehensive history of the pancreas like History of the Pancreas been published. It not only is a historical review of the science of medicine, it is liberally interspersed with anecdotal vignettes of the researchers who have worked on this organ. Much of it, such as the discovery of the duct of Wirsüng, of the islets of Langerhans, of insulin, gastrin and their tumors, reads like the adverture, which it is. This book, divided into 14 chapters, is written in a narrative style and is easily readable, as glimpses of the investigators, those who failed as well as those who succeeded, adds both perspective and human interest. Each chapter is completely referenced, totaling over 1500 references. As a reference book for students, teachers, investigators, writers, its detailed hjistorical documentation is unique. From the pre-Christian era of Asia Minor, to Greece, Rome, Europe and America, to the explosive progress in Japan, the history is there. History of the Pancreas: Mysteries of a Hidden Organ fills a gap.
Provides findings on acute pancreatitis in the fields of morphology, epidemiology, pathophysiology, enzymatic and in- strumental diagnosis, clinical aspects and pharmacological and surgical treatment. Emphasis on clinical implications on the local release and vasoactice and toxic substances, the high rate of bacterial infection in the necroses, and the causes of impairment of cardiocirculatory, pulmonary and re- nal organs.
A ‘moderately prosperous society’ with no Chinese individual left behind—that’s the vision for China set out by Chinese President Xi Jinping in a number of important speeches in 2017. ‘Moderate’ prosperity may seem like a modest goal for a country with more billionaires (609 at last count) than the US. But the ‘China Story’ is a complex one. The China Story Yearbook 2017: Prosperity surveys the important events, pronouncements, and personalitites that defined 2017. It also presents a range of perspectives, from the global to the individual, the official to the unofficial, from mainland China to Hong Kong and Taiwan. Together, the stories present a richly textured portrait of a nation that in just forty years has lifted itself from universal poverty to (unequally distributed) wealth, changing itself and the world in the process.
Late one night in December 2008, police arrived at the home of Liu Xiaobo—China’s leading dissident, a key figure in the prodemocracy manifesto Charter 08—and took him away. When Liu won the 2010 Nobel Peace Prize as a political prisoner, the award was bestowed on an empty chair. Inside China, the regime sought to erase every trace of his existence. Liu died of liver cancer in 2017 without ever having been allowed to return home. I Have No Enemies is the definitive biography of Liu Xiaobo, offering a meticulously researched account of the twists and turns of a remarkable life. Perry Link and Wu Dazhi explore Liu’s upbringing, immersion in classical Chinese poetry and philosophy, bold...