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Interventional Cardiology
The development of innovative interventional strategies and materials, primarily attributed to rapid strides in healthcare technology and education, has helped position interventional cardiology as one of the foremost disciplines in cardiovascular medicine. Patients diagnosed with inoperable conditions, including complex structural heart disease, have found renewed hope with the practice of these path-breaking therapeutic techniques. Nevertheless, the growing complexity of these procedures has also necessitated a close cooperation with different specialists, such as cardiothoracic surgeons, vascular surgeons, anesthesiologists, and interventional radiologists. There is an urgent need to further explore the use of such alternative strategies of clinical management of cardiac disease, while limiting or potentially eliminating any procedural risks for the patient. This book is oriented to readers interested in learning the basic principles of interventional cardiology and offers a brief insight into the potential use of such treatments in routine clinical practice.
Heart Rhythm Disorders
This engaging book covers a multitude of topics related to heart rhythm disorders (HRDs) and uniquely familiarizes readers with the development of treatment modalities over the past several decades, including the evolution of anti-arrhythmic drugs, pacemakers, defibrillators, and catheter ablation. Organized in ten sections, this title serves as both an archival and a contemporary resource for clinicians. The first section describes the discovery of the circulatory system by William Harvey in 1628 and outlines the development and understanding of HRD since the advent of intra-cardiac electrophysiology. Subsequent sections discuss the historical evolution of abnormal heart rhythms, such as su...
The Brugada Syndrome
Until recently, the cellular basis for sudden death, the BrugadaSyndrome, has largely remained an unknown to modernarrhythmologists and cardiologists, particularly in the absence ofany structural heart disease. Detailed observations of age-groups,especially the young, families and populations where sudden deathfrequently occurs, and improved understanding of its contributoryfactors and mechanisms are, however, showing the way forward. This addition to the Clinical Approaches to Tachyarrhythmias(CATA) Series, written by the investigators who discovered andprobed the Brugada Syndrome, discusses the history, etiology,pathology and clinical manifestations of sudden death. Fromdiagnosis, prognosi...
Hypoxic Pulmonary Vasoconstriction
Complete reference on hypoxic pulmonary vasoconstriction and hypoxia-mediated pulmonary hypertension. Can be utilized by the physician-scientist and researcher in the laboratory as both a technical manual and reference. Designed for clinicians to guide and improve clinical treatment and diagnosis of patients with hypoxia mediated pulmonary vascular disease and right heart failure.
Aortic Dissection and Related Syndromes
This state-of the-art publication is a result of the combined efforts of participants from the International Registry of Aortic Dissection (IRAD). It is the most comprehensive reference on aortic dissection The book has been divided into sections. Each chapter provides a succinct overview of the current clinical literature and incorporates illustrations for further explanation.
The ESC Handbook on Cardiovascular Pharmacotherapy
The ESC Handbook on Cardiovascular Pharmacotherapy, based on the most recent guidelines in cardiovascular pharmacology, and containing a comprehensive A-Z formulary of common and less commonly used cardiac drugs and drug groups, provides practical and accessible guidance on all areas of drug prescribing.
Cardiac Mechano-Electric Coupling and Arrhythmias
Ranging from stretch-activated ion channels to mechanically induced arrhythmias and mechanical interventions for heart rhythm correction, this new edition offers a thoroughly reviewed compendium of chapters, written by the top-experts in the world, on the mechanism and consequences of cardiac mechano-electrical coupling.
Implantable Defibrillator Therapy: A Clinical Guide
Implantable defibrillators as originally conceived by Michel Mirowski were limited to the detection and automatic termination of ventricular fibrillation. In the original "AID" device, the detection algoritlun sought to distinguish sinus rhytlun from ventricular fibrillation by identifying the "more sinusoidal waveform of ventricular fibrillation. " The therapeutic intervention was elicited only once deadly polymorphic rhythms had developed. It was rapidly learned, however, that ventricular fibrillation is usually preceded by ventricular tachycardia. Mirowski recognized the pivotal importance of developing algoritllms based on heart rate. Ventricular tachycardia detection allowed the success...
Mitochondria and the Heart
Mitochondria have been pivotal in the development of some of the most important ideas in modern biology. Since the discovery that the organelle has its own DNA and specific mutations were found in association with neuromuscular and cardiovascular diseases and with aging, an extraordi-nary number of publications have followed, and the term mitochondrial medicine was coined. Furthermore, our understanding of the multiple roles that mitochondria play in cardiac cell homeostasis opened the door for intensive experimentation to understand the pathogenesis and to find new treatments for cardiovascular diseases. Besides its role in adenosine triphosphate generation, mitochondria regu-late a complex...
