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Immunological Mechanisms and Therapies in Brain Injuries and Stroke
  • Language: en
  • Pages: 390

Immunological Mechanisms and Therapies in Brain Injuries and Stroke

Recent research has revealed the importance of immunological mechanisms and inflammation in delaying damage and/or promoting repair after an acute injury to the central nervous system. This book provides a comprehensive and up-to-date overview of the role of immunological mechanisms and therapies for treating acute neurological injuries such as cerebral ischemia, hemorrhage, and brain and spinal cord trauma. In several sections, the contributing authors provide a review of immunological mechanisms involved in neurological injury and of various translational and clinical research aimed at harnessing those mechanisms for better patient outcomes.​

Science and Public Reason
  • Language: en
  • Pages: 306

Science and Public Reason

  • Type: Book
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  • Published: 2012
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  • Publisher: Routledge

This book offers an empirically detailed, cross-nationally comparative account of the institutional logics and practices through which modern democratic governments construct public reason, that is, the forms of evidence and argument designed to persuade publics that legal and policy decisions are founded on reliable knowledge and expertise.

Brain Edema XVI
  • Language: en
  • Pages: 376

Brain Edema XVI

  • Type: Book
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  • Published: 2015-10-13
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  • Publisher: Springer

In this book, leading world authorities on brain edema and neurological disorders/injuries and experts in preconditioning join forces to discuss the latest progress in basic sciences, translational research, and clinical management strategies relating to these conditions. The range of topics covered is wide, including microglia, energy metabolism, trace metals and ion channels, vascular biology, cellular treatment, hemorrhagic stroke, novel technological advances, anesthesia and medical gases, pediatric brain edema, neuroimaging, behavioral assessment, clinical trials, peripheral to central signaling pathways, preconditioning translation, and animal models for preconditioning and brain edema research. The book comprises presentations from Brain Edema 2014, the joint meeting of the 16th International Conference on Brain Edema and Cellular Injury and the 3rd Symposium on Preconditioning for Neurological Disorders, held in Los Angeles on September 27–30, 2014.

Neutral Science Panels
  • Language: en
  • Pages: 116

Neutral Science Panels

  • Type: Book
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  • Published: 2001
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  • Publisher: Unknown

None

Innate Tolerance in the CNS
  • Language: en
  • Pages: 685

Innate Tolerance in the CNS

Cerebral preconditioning is a phenomenon wherein a mild insult or stress induces cellular and tissue adaptation or tolerance to a later, severe injury, therefore reflecting the efficacy of endogenous mechanisms of cerebrovascular protection. Initially identified for rapid cardiac protection, preconditioning has expanded to all aspects of CNS protection from ischemia, trauma and potentially neurodegeneration. Many different stimuli or stressors have been identified as preconditioning agents, suggesting a downstream convergence of mechanisms and underscoring the potential for translational application of preconditioning in the clinic. Moreover, the fundamental mechanisms responsible for precon...

Complex Sciences
  • Language: en
  • Pages: 350

Complex Sciences

  • Type: Book
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  • Published: 2013-11-08
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  • Publisher: Springer

This book constitutes the thoroughly refereed post-conference proceedings of the Second International ICST Conference on Complex Sciences, COMPLEX 2012, held in Santa Fe, New Mexico, USA in December 2012. The 29 revised full papers presented were carefully reviewed and selected from various submissions. The papers cover aspects on foundations and analysis of complex systems, complex biological systems, complex social systems, complex engineering systems.

Handbook of Stress and the Brain Part 2: Stress: Integrative and Clinical Aspects
  • Language: en
  • Pages: 485

Handbook of Stress and the Brain Part 2: Stress: Integrative and Clinical Aspects

  • Type: Book
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  • Published: 2005-02-25
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  • Publisher: Elsevier

The Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together the disciplines of neurobiology, physiology, immunology, psychology and psychiatry, to provide a reference source for both the non-clinical and clinical expert, as well as serving as an introductory text for novices in this field of scientific inquiry.Part 2 treats the complexity of short-term and long-term regulation of stress responsivity, the role of stress in psychiatric disorders as based on both preclinical and clinical evidence, and the current status with regard to new therapeutic strategies targetting stress-related disorders.

Translational Stroke Research
  • Language: en
  • Pages: 926

Translational Stroke Research

This volume sets a basis for effective translational research. Authored by experts in the field of translational stroke research, each chapter specifically addresses one or more components of preclinical stroke research. The emphasis is placed on target identification and drug development using state-of-the-art in vitro and in vivo assays, in combination with in vitro toxicology assays, AMDE and clinical design.

Biocomputing 2011
  • Language: en
  • Pages: 386

Biocomputing 2011

The Pacific Symposium on Biocomputing (PSB) 2011 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2011 will be held on January 3 7, 2011 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference. PSB 2011 will bring together top researchers from the US, Asia Pacific, and around the world to exchange research results and address pertinent issues in all aspects of computational biology. It is a forum fo...