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Novel clinical applications of extracellular vesicles
During the last years, the research on extracellular vesicles (EVs) has raised giving new insights into pathophysiology of several diseases. EVs are membrane-bound particles secreted by almost all cell types. Depending on their biogenesis and size they include exosomes, microparticles / microvesicles and apoptotic bodies. Characteristically, EVs carry markers from the source cell membrane and contain genetic material, lipids and proteins inside. They are known to play a role in cell-to-cell communication and to produce genotypic and phenotypic modifications in the target cell including: antigen presentation, apoptosis induction, cellular activation, inhibition or differentiation. In particul...
Novel Clinical Applications of Extracellular Vesicles
During the last years, the research on extracellular vesicles (EVs) has raised giving new insights into pathophysiology of several diseases. EVs are membrane-bound particles secreted by almost all cell types. Depending on their biogenesis and size they include exosomes, microparticles / microvesicles and apoptotic bodies. Characteristically, EVs carry markers from the source cell membrane and contain genetic material, lipids and proteins inside. They are known to play a role in cell-to-cell communication and to produce genotypic and phenotypic modifications in the target cell including: antigen presentation, apoptosis induction, cellular activation, inhibition or differentiation. In particul...
Stem Cell Drugs - A New Generation of Biopharmaceuticals
This invaluable resource discusses the current revolution in stem cell-based drugs and their potential use in clinical applications. Each chapter is contributed by a pre-eminent scientist in the field. An introductory section presents current stem cell drugs and stem cell-based products and a discussion of production, quality control, mechanisms, and efficacy. Following sections include discussions on stem cell-derived microvesicles based products, and derived exosomes based products. Stem Cell Drugs - A New Generation of Biopharmaceuticals and the other books in the Stem Cells in Clinical Applications series are invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering. This groundbreaking volume is also essential reading for those researching or studying drug development or pharmaceutical science.
About Trees
About Trees considers our relationship with language, landscape, perception, and memory in the Anthropocene. The book includes texts and artwork by a stellar line up of contributors including Jorge Luis Borges, Andrea Bowers, Ursula K. Le Guin, Ada Lovelace and dozens of others. Holten was artist in residence at Buro BDP. While working on the book she created an alphabet and used it to make a new typeface called Trees. She also made a series of limited edition offset prints based on her Tree Drawings.
Killing the Water
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Tango Lessons
From its earliest manifestations on the street corners of nineteenth-century Buenos Aires to its ascendancy as a global cultural form, tango has continually exceeded the confines of the dance floor or the music hall. In Tango Lessons, scholars from Latin America and the United States explore tango's enduring vitality. The interdisciplinary group of contributors—including specialists in dance, music, anthropology, linguistics, literature, film, and fine art—take up a broad range of topics. Among these are the productive tensions between tradition and experimentation in tango nuevo, representations of tango in film and contemporary art, and the role of tango in the imagination of Jorge Luis Borges. Taken together, the essays show that tango provides a kaleidoscopic perspective on Argentina's social, cultural, and intellectual history from the late nineteenth to the early twenty-first centuries. Contributors. Esteban Buch, Oscar Conde, Antonio Gómez, Morgan James Luker, Carolyn Merritt, Marilyn G. Miller, Fernando Rosenberg, Alejandro Susti
The Bride of Amman
The Bride of Amman, a huge and controversial bestseller when first published in Arabic, takes a sharp-eyed look at the intersecting lives of four women and one gay man in Jordan's historic capital, Amman-a city deeply imbued with its nation's traditions and taboos. When Rana finds herself not only falling for a man of the wrong faith, but also getting into trouble with him, where can they go to escape? Can Hayat's secret liaisons really suppress the memories of her abusive father? When Ali is pressured by society's homophobia into a fake heterosexual marriage, how long can he maintain the illusion? And when spinsterhood and divorce spell social catastrophe, is living a lie truly the best option for Leila? What must she do to avoid reaching her 'expiry date' at the age thirty like her sister Salma, Jordan's secret blogger and a self-confessed spinster with a plot up her sleeve to defy her city's prejudices? These five young lives come together and come apart in ways that are distinctly modern yet as unique and timeless as Amman itself.
Mud Sweeter than Honey
"[An] incredibly moving collection of oral histories . . . important enough to be added to the history curriculum" Telegraph "A moving evocation of the 'everyday terror' systematically perpetrated over 41 years of Albanian communism . . . An illuminating if harrowing insight into life in a totalitarian state." Clarissa de Waal, author of ALBANIA: PORTRAIT OF A COUNTRY IN TRANSITION "Albania, enigmatic, mysterious Albania, was always the untold story of the Cold War, the 1989 revolutions and the fall of the Berlin Wall. Mud Sweeter Than Honey goes a very long way indeed towards putting that right" New European After breaking ties with Yugoslavia, the USSR and then China, Enver Hoxha believed ...
Exosomes
Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomes in the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medical disciplines, as well as their role in cell-cell communication. It is intended to serve as a reference source for clinicians, physicians, and research scientists who wish to gain insight into the most recent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine since antibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is a major breakthrough in our understanding of how cells function. - Provide...
