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As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes, old and new diseases and adverse conditions. Indeed, complement became a term that almost defies categorization. What was for a long time a subject for a limited number of specialists has now moved into the mainstream of experimental and clinical immunology. In 1973 I visited the Basel Institute of Immunology and met its director, the eminent scientist and Nobel laureate Nils Jerne. When I entered his office he greeted me with the following word...
This is an open access book. In honor of his 75th birthday, we reflect on the impact of the pioneering work of Alan Grodzinsky and his laboratory. This volume includes in-depth discussions of tissue electromechanics, mechanobiology and biomechanics, and matrix biology in addition to the latest advancements in understanding the pathogenesis, progression and treatment of osteoarthritis. Unique to this volume, we overview decades of groundbreaking research that set the stage for the latest efforts in the field, highlighting the legacy of one researcher and their trainees.
Covers receipts and expenditures of appropriations and other funds.
This book explores why and how the design of architecture contributes to Christian pursuits of social and environmental justice. Edwards offers a new understanding of architectural design’s relation to Christian ethics and proposes five moral commitments for orienting the design process towards the flourishing of humanity and God’s creation.
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Buddhist-Christian dialogue has a long and complex history that stretches back to the first centuries of the common era. Comprising 42 international and disciplinarily diverse chapters, this volume begins by setting up a framework for examining the nature of Buddhist-Christian interreligious dialogue, discussing how research in this area has been conducted in the past and considering future theoretical directions. Subsequent chapters delve into: important episodes in the history of Buddhist-Christian dialogue; contemporary conversations such as monastic interreligious dialogue, multiple religious identity, and dual religious practice; and Buddhist-Christian cooperation in social justice, soc...