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Practical Approaches to Risk Minimisation for Medicinal Products
Risk management of medicines is a wide and rapidly evolving concept and practice, following a medicine throughout its lifecycle, from first administration in humans through clinical studies and then marketing in the patient population at large. Previous reports from CIOMS I - VIII provided practical guidance in some essential components of risk management such as terminology and reporting of adverse drug reactions, management of safety information from clinical trials, and safety signal detection. Beyond the detection, identification, and characterization of risk, "risk minimization" is used as an umbrella term for the prevention or mitigation of an undesirable outcome. Risk management alway...
Information Systems Development
Information Systems Development: Reflections, Challenges and New Directions, is the collected proceedings of the 20th International Conference on Information Systems Development held in Edinburgh, Scotland, August 24 - 26, 2011. It follows in the tradition of previous conferences in the series in exploring the connections between industry, research and education. These proceedings represent ongoing reflections within the academic community on established information systems topics and emerging concepts, approaches and ideas. It is hoped that the papers herein contribute towards disseminating research and improving practice
Optimizing Treatment for Children in the Developing World
This book is intended to communicate current best practice in pediatric clinical pharmacology and clinical pharmacy with special consideration of the prevailing circumstances and most pressing needs in developing countries. It also addresses measures that may be taken in countries with emerging economies through organizational and political adjustments to reduce unacceptable levels of morbidity and mortality among children and pregnant women with treatable diseases.
Enzymes in the Environment
The need to understand the biological processes that are important for essential aquatic and terrestrial ecosystem function has prompted much research into the field of ecological enzymology. This book presents the two broad areas of application in a compilation of reviews by 21 international experts in their respective fields. The first explores enzymatic activities to assess the processes or mechanisms that operate in a given system, such as the rhizosphere, plant leaves and shoots, soil surfaces, and biofilms. The second considers enzymes or microbial cells as sensors to detect microbial activity and stresses due to pollution, management, or climatic change in both aquatic and terrestrial ecosystems.
