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Diuretics: Basic, Pharmacological, and Clinical Aspects
The need for adequate means by which to improve urine output is very old. Even in the "Scuola Salernitana", the oldest medieval medical school in Western Europe, about 1000 years ago it was taught how to improve urine output. The list of known "diuretica" included herbs, plants, roots, vegetables, in particular asparagus, fennel and carrot. The first diuretic drugs, however, were mercurial compounds. Thus, calomel, mercurous chloride, was initially used as a diuretic in the sixteenth century by Paracelsus, being one of the ingredients of the so-called "Guy's Hospital pill". But calomel had a cathartic effect so that it was replaced by organic mercurial compounds. These diuretics were clearly...
Annual Reports in Medicinal Chemistry
Annual Reports in Medicinal Chemistry
Intracellular Protein Catabolism II
This book contains most of the papers presented . at the Second International Symposium on Intracellular Protein OItaboiism, which was held on May 26-30,1975 in Ljubljana, Yugoslavia. The papers presented in this book cover a wide variety of areas related to protein turnover and responsible enzymes. The symposium attracted about one hundred parti cipants, and the cordial atmosphere, the frank discussions and the exchange of ideas were a stimulant for all those attending_ During the last decade, investigations in the wide field of intracellular protein catabolism have been rapidly taken up in many laboratories, because the mechanisms and regulation of degradative processes are rather less stu...
Quantitative Coronary and Left Ventricular Cineangiography
In recent years there has been an increasing interest in quantitative analysis of coronary cineangiograms and already for a longer time of left ventricular cin eangiograms. The needfor quantitationofcoronary arterialdimensions has been stimulated by the introduction ofnew therapeutic procedures in the catheteriza tionlaboratory, suchas the balloon dilatationtechnique (PTCA) and thromboly tic therapy, by the need to study the vasoactive responses of pharmaceutical agents, and also by the desire to study the progressive nature ofcoronary artery disease with the ultimate goal to find ways to bring a halt to the progression of coronary atherosclerosis or even achieve regression of the disease. P...
Journal of Cardiovascular Surgery
Some vols. include special issues covering the proceedings of the congresses of the European Society of Cardiovascular Surgery or the International Cardiovascular Society.
