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Spinal Interneurons: Plasticity after Spinal Cord Injury provides neuroscientists, clinicians and trainees a reference book exclusively concentrating on spinal interneurons and the techniques and experiments employed to identify and study these cells as part of normal, diseased and injured neural circuits. In addition, the book highlights the therapeutic potential of these cells by presenting relevant pre-clinical and clinical work that has been performed. The book's focus on the latest in therapeutic strategies for targeting spinal interneurons, considerations for the development and use of treatments, and how such treatments work make this a comprehensive source of information. Provides a comprehensive overview of the techniques used to identify, characterize and classify spinal interneurons and their role in neural circuits Presents an in-depth discussion of the therapeutic potential of spinal interneurons for SCI injury and/or disease Represents the first book to discuss spinal interneurons and translational research
The spinal cord is comprised of four types of neurons: motor neurons, pre-ganglionic neurons, ascending projection neurons, and spinal interneurons. Interneurons are neurons that process information within local circuits, and have an incredible ability for neuroplasticity, whether due to persistent activity, neural injury, or in response to disease. Although, by definition, their axons are restricted to the same structure as the soma (in this case the spinal cord), spinal interneurons are capable of sprouting and rewiring entire neural circuits, and contribute to some restoration of disrupted neural communication after injury to the spinal cord (i.e., “bypassing the lesion site). Spinal In...
This ambitious work chronicles 250 years of the Cromartie family genealogical history. Included in the index of nearly fifty thousand names are the current generations, and all of those preceding, which trace ancestry to our family patriarch, William Cromartie, who was born in 1731 in Orkney, Scotland, and his second wife, Ruhamah Doane, who was born in 1745. Arriving in America in 1758, William Cromartie settled and developed a plantation on South River, a tributary of the Cape Fear near Wilmington, North Carolina. On April 2, 1766, William married Ruhamah Doane, a fifth-generation descendant of a Mayflower passenger to Plymouth, Stephen Hopkins. If Cromartie is your last name or that of on...