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Michael Kane
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Country Never Trod
William Lewis Manly was a forty-niner, explorer, and humanitarian whose story most people have never heard. Born in Vermont, William Lewis Manly was drawn out west by the lure of gold. Previous scholarship claims that the Yankee frontiersman floated only 290 miles down the Green River to the Uinta Basin, but author Michael D. Kane’s research of primary source materials led him to the conclusion that Manly actually traveled 415 miles, all the way to what is now Green River, Utah. This would make Manly the first to explore much of the Green River by boat—twenty years before John Wesley Powell’s famous expedition. Determined to prove his theory and establish Manly’s legacy as a trailblazer, Kane conducted research and then built his own wooden canoes and made the trip, tracing Manly’s footsteps and comparing notes with the earlier traveler. Country Never Trod follows Manly’s little-known expedition down the Green River and his overland trek through some of the most desolate stretches of Utah, interspersed with Kane’s journal entries and photographs documenting his own trip.
Heal Your Broken Heart
Based on the highly successful Los Angeles workshop by the same name, Heal Your Broken Heart is an easy-to-follow process that gently guides us through understanding, releasing, and ultimately healing our heartbreak from a lost romantic relationship. The book is filled with extraordinary tools and superb guidance we can all use. In his direct, easy tone Michael Kane teaches us how to heal from both our past and present heart wounding as we also learn to identify our relationship patterns. The result gives us a renewed connection to ourselves, a refreshed sense of self-confidence and personal awareness, and a healthy approach to our future relationships. Heal Your Broken Heart is also a primer on love, clarifying what love is and inspiring us to love and nurture ourselves as we mend from our heartache. This is a book for both women and men that teaches us how to process through our pain and fully recover from it.
Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine
Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine provides a primer to understand pharmacogenetics (the study of genetic factors that influence how a drug works) in the applied context of pharmacokinetics (how the body handles a drug) and pharmacodynamics (the effects of a drug on the body). This valuable foundation illuminates how these principles and scientific advances can create optimal individual patient care, that is, "personalized medicine." Through specific drug examples, this resource explores how the genetic constitution of an individual may lead to the need for an altered dose or in some cases alternative drug therapy. Real-world cases highlight the specific relationships between genetics, drug action, and the body's response as well as adverse drug reactions, altered metabolism, and drug efficacy. Ethical issues concerning pharmacogenomics and study design are also discussed in this concise overview.
Farmer Cooperatives
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Startup Cities
This book offers a comprehensive model for explaining the success and failure of cities in nurturing startups, presents detailed case studies of how participants in that model help or hinder startup activity, and shows how to apply these lessons to boost local startup activity. Startup Cities explains the factors that determine local startup success based on a detailed comparison of regional startup cities—pairing the most successful and less successful cities within regions along with insights and implications from case studies of each of the model’s elements. The book compares local city pairs, highlighting factors that distinguish successful from less successful cities and presents im...
