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Handbook of Alcoholism
While the war on drugs continues to attract world attention, it is often overlooked that alcoholism remains a major worldwide health concern. No matter what your expertise, the CRC Handbook of Alcoholism can help you acquire the necessary skills to treat problem drinkers and alcohol-dependent patients. In three sections - Patient Care, Research,
The Liver
Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries ...
Unmaking Waste
Explores the concept of waste from fresh historical, cultural, and geographical perspectives. Garbage is often assumed to be an inevitable part and problem of human existence. But when did people actually come to think of things as “trash”—as becoming worthless over time or through use, as having an end? Unmaking Waste tackles these questions through a long-term, cross-cultural approach. Drawing on archaeological finds, historical documents, and ethnographic observations to examine Europe, the United States, and Central America from prehistory to the present, Sarah Newman traces how different ideas about waste took shape in different times and places. Newman examines what people consid...
Molecular Pathology of Liver Diseases
Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy...
Burgmannshofer Hofgeschichten
Die Burgmannshofer Hofgeschichten stellen eine Chronik der alten bäuerlichen Hofstellen in Burgmannshofen über die letzten Jahrhunderte bis in die Nachkriegszeit dar. Für jede Hofstelle fügen sich vergangene Eigentums- und Besitzverhältnisse, sachliche Beschreibungen, Lebensdaten der Bewohner, Aufzeichnungen der hiesigen Pfarrer sowie Erzählungen der ältesten Dorfbewohner zu einer umfassenden chronologischen Hofgeschichte zusammen. Darüber hinaus werden die Kirche St. Gertraud und das Armen- und Hirtenhaus in eigenen Kapiteln behandelt. Eine Auflistung ehemaliger Dorfbewohner ohne Hofzuordnung, ein kurzer Abriss zur Dorfentwicklung und ein Glossar runden die Publikation ab, ergänzt mit 50 Abbildungen, Flurkarten und einem wissenschaftlich akkuraten Quellen- und Literaturverzeichnis.
Textbook of Hepatology
THE encyclopedic guide to hepatology – for consultation by clinicians and basic scientists Previously the Oxford Textbook of Clinical Hepatology, this two-volume textbook is now with Blackwell Publishing. It covers basic, clinical and translational science (converting basic science discoveries into the practical applications to benefit people). Edited by ten leading experts in the liver and biliary tract and their diseases, along with outstanding contributions from over 200 international clinicians, this text has global references, evidence and extensive subject matter – giving you the best science and clinical practice discussed by the best authors. It includes unique sections on: Symptoms and signs in liver disease Industrial diseases affecting the liver The effects of diseases of other systems on the liver The effects of liver diseases on other systems It's bigger and more extensive than other books and discusses new areas in more depth such as stem cells, genetics, genomics, proteomics, transplantation, mathematics and much more. Plus, it comes with a fully searchable CD ROM of the entire content. Click here to view a sample chapter on the liver and coagulation
Plastic Legacies
There is virtually nowhere on earth that remains untouched by plastics and the situation presents a serious threat to our natural world. Despite the magnitude of the problem, the interventions most often put in place are consumer-led and market-based and only nominally capable of addressing the issue. As the problem worsens and neoliberal ideologies limit the world’s responses to this crisis, there is a growing need for legislative frameworks that attend to the complex social and ecological issues associated with plastics. The contributors to this volume bring expertise from across academic disciplines to illustrate how plastics are produced, consumed, and discarded and to find holistic an...
Hepatobiliary Transport in Health and Disease
One major function of the liver is the uptake of endo- and xenobiotics from the bloodstream and their excretion into bile. The transport systems involved in hepatobiliary transport have been recently cloned and characterized at the molecular level and it is becoming clear that mutations and polymorphisms of individual transporter molecules underlie a variety of liver diseases. Furthermore, new research has shown that bile acids, whose function in digestion is long known, also behave as signal molecules in a variety of organs, including the intestinal and biliary epithelia, sinusoidal endothelial and immune cells. This book provides indepth surveys on the structure and function of transport molecules involved in hepatobiliary transport, on the role of different bile acids receptors in various organs and their function in health and disease, the mechanisms of bile salt-induced apoptosis and hepatocyte protection, and the role of transporter mutations as causes and modifiers of liver diseases. The book will be of interest not only for biochemists, structural chemists and biologists, but also for clinicians.
Signaling Pathways in Liver Diseases
Signaling Pathways in Liver Diseases, 2nd edition focuses on signaling pathways which are particularly important in liver diseases. Recent progress brought hepatology to new frontiers. The increasing frequency of surgery on steatotic and cirrhotic liver obliges liver surgeons and hepatologists to understand the molecular mechanisms at play in these situations and how they can be influenced. Better comprehension of the cellular mechanisms participating in liver regeneration, hepato-cellular apoptosis and ischemia/reperfusion inquiry is mirrored by a dramatic increase in complexity. The number and scope of publications is intimidating and difficult for busy individuals to extract a coherent framework. This book will serve as a source of information facilitating the reading of the literature and the planning of trials. Translational medicine implies knowledge of the molecular targets for novel therapeutic strategies. It will furthermore stimulate more research and lead to better exchange between the laboratory, the clinical ward and the operation room.
Transporters as Drug Targets
As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease.
