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Oxidative Stress
Since the discovery of free radicals in biological systems researchers have been highly interested in their interaction with biological molecules. Denoted in 1980, and due to fruitful results and ideas, oxidative stress is now appreciated by both basic and applied scientists as an enhanced steady state level of reactive oxygen species with wide range of biological effects. This book covers a wide range of aspects and issues related to the field of oxidative stress. The association between generation and elimination of reactive species and effects of oxidative stress are also addressed, as well as summaries of recent works on the signaling role of reactive species in eukaryotic organisms. The readers will gain an overview of our current understanding of homeostasis of reactive species and cellular processes they are involved in, as well as useful resources for further reading.
Development and Neurobiology of Drosophila
There is no multicellular animal whose genetics is so well understood as Drosophila melanogaster. An increasing number of biologists have, therefore, turned to the fruitfly in pursuit of such diverse areas as the molecular biology of eukaryotic cells, development and neurobiology. Indeed there are signs that Dro sophila may soon become the most central organism in biqlogy for genetic analysis of complex problems. The papers in this collection were presented at a conference on Development and Behavior of Drosophila held at the Tata Insti tute of Fundamental Research from 19th to 22nd December, 1979. The volume reflects the commonly shared belief of the participants that Drosophila has as much...
Prostate Cancer
Prostate Cancer, Science and Clinical Practice, Second Edition, continues to be an important translational reference that bridges the gap between science and clinical medicine. It reviews the biological processes that can be implicated in the disease, reviews current treatments, highlights the pitfalls where relevant, and examines the scientific developments that might result in future treatments. Key chapters from the previous edition have been updated, and a plethora of new chapters describe new concepts of prostate cancer biology and newly developed therapeutics. Each chapter has been written by internationally recognized specialists on prostate cancer epidemiology, genetic susceptibility...
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Comprehensive Insect Physiology, Biochemistry, and Pharmacology
Volume 2 on Postembryonic Development deals with such topics as life cycles, structural analysis, imaginal discs, cuticular proteins, intercellular communication, polytene chromosomes, muscle structure and maturation, and regeneration. The chapters show that generality of cell development is to be found in insects, in contrast to the more specialized cells of vertebrates. The way that insect cells preserve their relationships to one another in simple geometries within tubes and sheets has allowed experiments that have given the first records of segmentally repeating gradients and compartments, the first quantitative accounts of the way that cells are coupled, the first descriptions of the remodelling of gap junctions and the modulation of junctional conductivity by hormones. This volume provides up-to-date accounts that will be of value not only to entomologists but also to all researchers in cell and developmental biology.
Maintenance of Genome Integrity: DNA Damage Sensing, Signaling, Repair and Replication in Plants
Environmental stresses and metabolic by-products can severely affect the integrity of genetic information by inducing DNA damage and impairing genome stability. As a consequence, plant growth and productivity are irreversibly compromised. To overcome genotoxic injury, plants have evolved complex strategies relying on a highly efficient repair machinery that responds to sophisticated damage perception/signaling networks. The DNA damage signaling network contains several key components: DNA damage sensors, signal transducers, mediators, and effectors. Most of these components are common to other eukaryotes but some features are unique to the plant kingdom. ATM and ATR are well-conserved member...
Climate Change and Plant Abiotic Stress Tolerance
In this ready reference, a global team of experts comprehensively cover molecular and cell biology-based approaches to the impact of increasing global temperatures on crop productivity. The work is divided into four parts. Following an introduction to the general challenges for agriculture around the globe due to climate change, part two discusses how the resulting increase of abiotic stress factors can be dealt with. The third part then outlines the different strategies and approaches to address the challenge of climate change, and the whole is rounded off by a number of specific examples of improvements to crop productivity. With its forward-looking focus on solutions, this book is an indispensable help for the agro-industry, policy makers and academia.
