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Since the discovery of free radicals in biological systems researchers have been highly interested in their interaction with biological molecules. Denoted in 1980, and due to fruitful results and ideas, oxidative stress is now appreciated by both basic and applied scientists as an enhanced steady state level of reactive oxygen species with wide range of biological effects. This book covers a wide range of aspects and issues related to the field of oxidative stress. The association between generation and elimination of reactive species and effects of oxidative stress are also addressed, as well as summaries of recent works on the signaling role of reactive species in eukaryotic organisms. The readers will gain an overview of our current understanding of homeostasis of reactive species and cellular processes they are involved in, as well as useful resources for further reading.
John Alexander Kelly, son of Vincent Kelly and Ann Simmons Alexander, was born 23 Jun 1821 in Lee County, Virginia. Martha Matilda Peck, daughter of John Peck and Elizabeth Snidow, was born 26 Aug 1827 in Giles County, Virginia. They married on 23 Oct 1843 in Giles County. They had thirteen children. Martha died 3 July 1890 and John died 17 Nov 1900. They are buried in Marion, Virginia. Their ancestors and descendants have lived in Virginia, Maryland, New Jersey, West Virginia and other areas throughout the United States.