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Processing of Slender Concrete Shells - Fabrication and Installation
Lightweight structures and material optimized systems are of major relevance in the building industry and particularly in the design of concrete structures. This is not only for aesthetic reasons, but also to use material in a resource conserving way. The increase of strength characteristics, as one measure to reduce cross section dimensions, postulates the prefabrication of cementitious materials under laboratory conditions. This thesis examines the contradiction of the possibility to realize slender concrete elements and the complexity of the discontinued homogeneity arising from necessary segmentations. Proposals of implementation strategies are demonstrated and verified on the basis of selected case studies.
Informed Form Generation
Over the past decades we witnessed a tremendous shift in the principles of architectural design based on the advancement of computer aided design and manufacturing. Computation in architecture came with a whole new set of techniques as well as theories that did change the way we build and design today. This research investigates ways to embed computational simulation and optimisation into architectural design processes at an early, conceptual stage. Simulation and optimization are not seen as a post-design strategy to improve performance aspects of a well-developed design, but rather as design strategies in their own rights. Therefore, design approaches employing simulation and optimization ...
Cyclic Nucleotide Signaling and the Cardiovascular System
This book is a printed edition of the Special Issue "Cyclic Nucleotide Signaling and the Cardiovascular System" that was published in JCDD
LAVA Laboratory for Visionary Architecture
Monograph questioning What if research, science and architecture were merged? LAVA is an architecture studio founded by Tobias Wallisser, Chris Bosse, and Alexander Rieck with offices in Germany, Vietnam, and Australia. The German Pavilion for Expo 20 is an example of the eloquence with which LAVA responds to issues of the day. The three core themes of the book – Cities of the Future, Biodiversity, as well as Energy and Sustainability – are complemented by the subjects “Connecting Minds,” meaning social and political architecture, “Digital Processes and Technologies,” and “New Work” and explored together throughout the six chapters of this book. In addition to projects and their derivation, architectural and sociological thinkers elaborate on their ideas on these topics – creatively, speculatively, and thoughtfully. Themes: City – Energy – Biodiversity – Connecting – Work – Digital Processes Selected projects as case studies With contributions by Amy Frearson, Georg Vrachliotis, Giovanna Carnevali, Maria Aiolova, Gilles Retsin, André Wilkens, Marjan Colletti, and Raoul Bunschoten
Genetic Causes of Cardiac Disease
This book provides a comprehensive summary of the latest developments in the field of the genomics of cardiac disease. Written and edited by leading clinicians and scientists involved in the analysis and therapy of genetic cardiac disorders, it discusses the genetic causes of a variety of cardiac diseases, such as the complex genetics and etiology of congenital heart diseases. It also explores sex differences in prevalent diseases, genetics-based therapeutic strategies and the use of various animal models and alternatives. The book is intended for research scientists and clinical scientists in the cardiovascular field, human geneticists and cardiologists.
Queen's Apprentice
This study seeks to examine a number of themes relating to the roles of the women's court of the central European Habsburgs. These include its role in helping consolidate their holdings in central Europe and the Holy Roman Empire and structure their relations with the rest of Europe.
A New Manifold
A NEW MANIFOLD, the inaugural issue of SAC JOURNAL, addres- ses the increased specialisation and possible fragmentation of ex- pertise within architecture. Whilst historically always an amalgam of numerous forms of input, architecture is currently facing the necessi- ty to assimilate and process hitherto unknown amounts and rates of information flow. How can architecture relate to the emerging forms of specialisation within the discipline - not the least in its pedagogy and academic programmes? The issue uses the academic programme of the Städelschule Architecture Class to reflect on these questions. The work presented comprises the finalists for the AIV Master Thesis Prize 2013.
SAC Journal 2
MEDIATED ARCHITECTURE: Vivid, Effervescent and Nervous, the second issue of the SAC JOURNAL, presents three projects de- signed at SAC during the last eight years. The three projects are: The Theatre of Immanence (2007), an installation and exhibition project in Städelschule's Portikus gallery; Digital Bodies (2013-14), an experimental research project; and Orkhēstra (2014), which was an installation on a large, public square in Frankfurt and part of Luminale, 'Biennale of Lighting Culture'. The projects vary in scale and nature from gallery installation via laboratory-style modelling experiment to an urban intervention. They span a period in which architecture's contribution to the production of space has become increasingly me- diated by technology. Each in their own way, the three projects probe this condition and explore new design opportunities given to archi- tecture. The results are vivid, effervescent and nervous – and always a mediated architecture. Accompanying extensive portfolios of drawi- ngs and pictures that document the respective design processes and their results, are texts that expound on the theoretical and practical implications of each project
Reactive Oxygen Species
Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach ...
Structural Surface
This publication presents the computational design, optimization and realization of a freeform object from high performance concrete. It illustrates the design phase, the manufacturing and the so called Mobiusbank itself. Moreover, two short papers give comprehensive explanations of the employed computational structural optimization as well as a novel joining technique developed for the project.
