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Pseudo-peptides in Drug Discovery
Peptide gehören zu den vielseitigsten bioaktiven Molekülen überhaupt. Trotzdem ist ihre Eignung als pharmazeutische Wirkstoffe beschränkt, da sie im Körper rasch abgebaut oder verändert werden. Um dieses Problem zu lösen sind stabile und gleichzeitig biologisch aktive Pseudopeptide entwickelt worden. Diese Verbindungen erschließen neue Perspektiven in der Medikamentenentwicklung und stellen eine ganze Palette neuartiger hochspezifischer und nicht-toxischer Pharmazeutika zur Verfügung. Erstmalig ist hier das gesamte Wissen zusammengefasst, das über verschiedene Arten von Peptidomimetika und andere Pseudopeptide mit Einsatzmöglichkeiten in der Pharmaforschung gewonnen wurde. Peptoide, Beta - Peptide, DNA-bindende Polyamide sowie Peptid-Nucleinsäuren werden hier behandelt. Ausgewiesene Experten diskutieren chemische Eigenschaften und Stabilität, biologische Aktivität und Reaktivität, sowie praktische Aspekte der Synthese und machen dieses Werk damit zur essentiellen Informationsquelle für alle Medikamentenentwickler und bioorganische Chemiker, die mit diesen Verbindungen arbeiten.
Chemical Sciences
Selected peer-reviewed extended articles based on abstracts presented at the 4th International Conference on Chemical Science (ICCS, 2021) Aggregated Book
Innovation for Sustainable Development
8th RMUTP ICON SCi-2017 Selected, peer reviewed papers from the 8th RMUTP International Conference on Science, Technology and Innovation for Sustainable Development: Challenges towards the Digital Society 2017 (8th RMUTP ICON SCi-2017), June 22-23, 2017, Bangkok, Thailand
Diversity Oriented Synthesis
Has the concept of Diversity Oriented Synthesis remained unchanged over these two decades, or do we observe improvements or deviations from the original guidelines drawn by the pioneers? The aim of this Research Topic is to collect contributions on the state-of-the-art and progress of Diversity Oriented Synthesis, and to foresee its shape in the next decade.
Advanced Materials and Manufacturing Engineering II
Selected peer-reviewed full text papers from the 3rd International Conference on Materials Science and Manufacturing Technology (ICMSMT 2021) Selected peer-reviewed full text papers from the 3rd International Conference on Materials Science and Manufacturing Technology (ICMSMT 2021), April 08-09, 2021, Tamil Nadu, India
Engineering Tribology and Biomedical Materials
Selected peer-reviewed full text papers from the 4th PST and 2nd ICETAT
Isocyanide Chemistry
The efficacy of isocyanide reactions in the synthesis of natural or naturallike products has resulted in a renaissance of isocyanide chemistry. Now isocyanides are widely used in different branches of organic, inorganic, coordination, combinatorial and medicinal chemistry. This invaluable reference is the only book to cover the topic in such depth, presenting all aspects of synthetic isonitrile chemistry. The highly experienced and internationally renowned editor has brought together an equally distinguished team of authors who cover multicomponent reactions, isonitriles in total synthesis, isonitriles in polymer chemistry and much more.
International Conference on Engineering Tribology and Applied Technology
Selected peer-reviewed full text papers from the 2nd International Conference on Engineering Tribology and Applied Technology (ICETAT 2020) Selected, peer-reviewed papers from the 2nd International Conference on Engineering Tribology and Applied Technology (ICETAT 20), November 06-08, 2020, Chiayi, Taiwan
Technology and Innovation for Sustainable Development: Turning Digital Disruptions into Opportunities
Selected peer-reviewed papers from the 10th RMUTP International Conference on Science, Technology and Innovation for Sustainable Development: Turning Digital Disruptions into Opportunities 2019 (10th RMUTP ICON SCi-2019)
Anion-Binding Catalysis
Explores the potential of new types of anion-binding catalysts to solve challenging synthetic problems Anion-Binding Catalysis introduces readers to the use of anion-binding processes in catalytic chemical activation, exploring how this approach can contribute to the future design of novel synthetic transformations. Featuring contributions by world-renowned scientists in the field, this authoritative volume describes the structure, properties, and catalytic applications of anions as well as synthetic applications and practical analytical methods. In-depth chapters are organized by type of catalyst rather than reaction type, providing readers with an accessible overview of the existing classe...
