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Handbook of HER2-Targeted Agents in Breast Cancer
This concise handbook provides oncologists and other healthcare providers with crucial updates in the field, including an updated review of the current understanding of the biology of the HER2 pathway, an overview of HER2-testing, and evidence-based discussions of available and emerging HER2-targeted treatment options. An essential clinical text for physicians that screen and treat patients with breast cancer and require an accessible, up-to-date survey of the dynamic treatment landscape.
Molecular Oncology of Breast Cancer
The first comprehensive reference to focus on the molecular development and treatment of the disease, Molecular Oncology of Breast Cancer provides authoritative information across the spectrum of modern breast cancer research and clinical care. Edited by two world-class experts in cancer pathology, drug development, and patient management, with contributions from over 50 experts, this ground-breaking text describes the genes, proteins, and biologic pathways that are being evaluated today and will be tested in the future to derive the molecular signature of each newly diagnosed breast cancer. For the first time, readers can now obtain, in a single volume, up-to-date information on how molecular-based tests are being used to identify predisposition, provide earliest detection, decide classification based on genetic fingerprint and predict therapy-specific outcomes. MOBC includes unique chapters on functional imaging and the impact of targeted therapies on the FDA approval process. This book gives readers vital, up-to-date information on important molecular discoveries that affect the everyday management of the breast cancer patient.
Advances in Clinical Chemistry
Volume 45 of the Advances in Clinical Chemistry series contains review articles of wide interest to clinical laboratory scientists and diagnostic adventurers. Articles in this volume cover such topics as Inhibins as Diagnostic Markers in Human Reproduction; uPA and PAI-1 in Breast Cancer: Review of Their Clinical Utility and Current Validation in the Prospective NNBC-3 Trial; Advances in Multiple Analyte Profiling; Immune Monitoring of Clinical Trials with Biotherapies; Dietary Modification of Brain Function: Effects on Neuroendocrine and Psychological Determinants of Mental Health and Stress Related Disorders; Menopause, Estrogen and Gonadotropins in Alzheimer's Disease; Immunosuppression Routed via the Kynurenine Pathway: A Biochemical and Pathophysiologic Approach; and Pathophysiology of Tumor-associated Macrophages.
Reviews in Breast Cancer: 2023
Frontiers in Oncology is delighted to present the ‘Reviews in’ series of article collections. Reviews in Breast Cancer will publish high-quality review articles on key topics in the field. It aims to highlight recent advances in the field, whilst emphasizing important directions and new possibilities for future inquiries. The Reviews in Breast Cancer collection welcomes full-length, mini or systematic review papers. New articles will be added to this collection as they are published.
Breast Cancer Research Protocols
A collection of both well-established and cutting-edge methods for investigating breast cancer biology not only in the laboratory, but also in clinical settings. These readily reproducible techniques solve a variety of problems, ranging from how to collect, store, and prepare human breast tumor samples for analysis, to analyzing cells in vivo and in vitro. Additional chapters address the technology of handling biopsies, new methods for analyzing genes and gene expression, markers of clinical outcome and progress, analysis of tumor-derived proteins and antigens, validating targets, and investigating the biology of newly discovered genes.
Brazil in Advancing Pharmacotherapy and Clinical Pharmacy in Latin America
The Fourth Brazilian Congress of Pharmacotherapy and Clinical Pharmacy showcases Brazil's role within the vibrant and evolving community of pharmacotherapy and clinical pharmacy in Latin America. This volume offers a window into Brazil's ongoing contributions as part of a collective Latin American effort, presenting a comprehensive collection of scientific investigations and documented clinical experience reports that address important healthcare challenges. Containing hundreds of peer-reviewed works, evaluated through a double-blind review process, this publication documents ongoing progress in evidence-based, patient-centered pharmaceutical care. The compilation adheres to rigorous scientific standards, with submissions evaluated for methodological soundness, clinical relevance, and adherence to ethical guidelines. Systematically organized to facilitate knowledge transfer, this resource offers understandings into emerging therapeutic protocols, pharmacological interventions, and clinical decision-making frameworks. For researchers, clinicians, and policymakers, this publication provides an essential, data-driven foundation for advancing pharmaceutical practice in the region.
Prioritizing Global Responsibilities
States face multiple ongoing and emerging challenges, from climate change to global disease, mass atrocities to forced displacement, humanitarian crises to entrenched global poverty, and are constrained by material and political limits to the amount of resources that they can devote to these issues. How should states decide which issues to prioritize and which crises to address? Prioritizing Global Responsibilities answers this question by proposing a two-level account of just prioritization that aims to be both philosophically sound and practically relevant. The authors assess several potential prioritization principles, including diversification, culpability, urgency, disadvantage, and national interest, and argue that states should prioritize issues where they can assist most effectively and where they can help those who are most underprivileged.
