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Measuring Resting Cerebral Perfusion using Magnetic Resonance Imaging (MRI)
The acquisition of resting cerebral perfusion measures using magnetic resonance imaging (MRI) is one of the assessments of cerebrovascular health used to discern how well patients are coping with anatomical changes such as stenosis, and other factors impacting the supply of blood flow to the brain. Perfusion measures may be obtained using several MRI based techniques including arterial spin labeling (ASL) and dynamic contrast enhanced methods that rely on injected contrast agents such as gadolinium. Recently hypoxia-induced changes in deoxyhemoglobin have been used as a non-invasive contrast agent, measuring the resulting changes in blood oxygen dependent (BOLD) signals with MRI. With each approach, the means through which voxel-wise cerebral perfusion information is derived differs, leading to the development a variety of analysis methods in recent studies. This Research Topic is intended to attract manuscripts that advance the use of resting cerebral perfusion measures in clinical assessments of cerebrovascular health. In pursuit of this aim a better understanding of several aspects are needed.
Imaging Cerebrovascular Reactivity: Physiology, Physics and Therapy
Topic Editor Prof. James Duffin contributed to the development of an automated end-tidal targeting device, RespirActTM and is employed by Thornhill Medical Inc. (Toronto, Canada). RespirActTM is currently a non-commercial research tool assembled and made available by TMI to research institutions to enable CVR studies. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Cerebrovascular Reactivity
This volume provides a comprehensive overview of the methodology, physiology, and contemporary and novel applications of cerebrovascular reactivity (CVR) measurements. The chapters in this book cover topics such as an introduction of the neurophysiology, neuroimaging, and clinical methods for CVR measurement; the use of CVR methods in the study of aging, cerebrovascular dysfunction, dementia, and brain tumors; and recommendations for measurement protocols and future applications in clinical translation. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your research center and clinical investigation. Thorough and comprehensive, Cerebrovascular Reactivity: Methodological Advances and Clinical Applications is a valuable tool that provides researchers in neuroscience and neurology with the latest resources on the measurement, interpretation, and application of CVR measurement.
John Blockley – A Retrospective
John Blockley was one of Britain's most outstanding watercolour and pastel painters of the late 20th century, and has exhibited at the Royal Academy. Self-taught, he produced work that has always been experimental and progressive. His highly textured style was well ahead of his time and still hugely influential now. The quality of his work is even more staggering given that he never trained at any art college, and spent most of his working life as an engineer. He only started painting full time at the age of 52. His obsession for drawing and painting, even while a successful engineer, was driven by his search for the essence of his subjects. The power of his paintings reveal that passion. Th...
Human Physiology
This book explores the field of human physiology, considering the interplay of physiological mechanisms and principles and how they come together to result in human life being sustained. It also discusses how physiological experiments are undertaken, and covers the medical applications of new discoveries.
The Harlem Renaissance
This Very Short Introduction offers an overview of the Harlem Renaissance, a cultural awakening among African Americans between the two world wars. Cheryl A. Wall brings readers to the Harlem of 1920s to identify the cultural themes and issues that engaged writers, musicians, and visual artists alike.
Agriculture
From the large corporation using enormous machines in the USA, to the woman with her hoe and her plot of cassava in Mozambique, to a Chinese collective farm worker in the rice fields, agriculture is essential for humanity to eat. This book looks at the many different types of agriculture and considers the challenges facing farmers today.
