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Measuring Resting Cerebral Perfusion using Magnetic Resonance Imaging (MRI)
The acquisition of resting cerebral perfusion measures using magnetic resonance imaging (MRI) is one of the assessments of cerebrovascular health used to discern how well patients are coping with anatomical changes such as stenosis, and other factors impacting the supply of blood flow to the brain. Perfusion measures may be obtained using several MRI based techniques including arterial spin labeling (ASL) and dynamic contrast enhanced methods that rely on injected contrast agents such as gadolinium. Recently hypoxia-induced changes in deoxyhemoglobin have been used as a non-invasive contrast agent, measuring the resulting changes in blood oxygen dependent (BOLD) signals with MRI. With each approach, the means through which voxel-wise cerebral perfusion information is derived differs, leading to the development a variety of analysis methods in recent studies. This Research Topic is intended to attract manuscripts that advance the use of resting cerebral perfusion measures in clinical assessments of cerebrovascular health. In pursuit of this aim a better understanding of several aspects are needed.
Cerebrovascular Reactivity
This volume provides a comprehensive overview of the methodology, physiology, and contemporary and novel applications of cerebrovascular reactivity (CVR) measurements. The chapters in this book cover topics such as an introduction of the neurophysiology, neuroimaging, and clinical methods for CVR measurement; the use of CVR methods in the study of aging, cerebrovascular dysfunction, dementia, and brain tumors; and recommendations for measurement protocols and future applications in clinical translation. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your research center and clinical investigation. Thorough and comprehensive, Cerebrovascular Reactivity: Methodological Advances and Clinical Applications is a valuable tool that provides researchers in neuroscience and neurology with the latest resources on the measurement, interpretation, and application of CVR measurement.
John Blockley – A Retrospective
John Blockley was one of Britain's most outstanding watercolour and pastel painters of the late 20th century, and has exhibited at the Royal Academy. Self-taught, he produced work that has always been experimental and progressive. His highly textured style was well ahead of his time and still hugely influential now. The quality of his work is even more staggering given that he never trained at any art college, and spent most of his working life as an engineer. He only started painting full time at the age of 52. His obsession for drawing and painting, even while a successful engineer, was driven by his search for the essence of his subjects. The power of his paintings reveal that passion. Th...
Agriculture
From the large corporation using enormous machines in the USA, to the woman with her hoe and her plot of cassava in Mozambique, to a Chinese collective farm worker in the rice fields, agriculture is essential for humanity to eat. This book looks at the many different types of agriculture and considers the challenges facing farmers today.
Modern China
"Rana Mitter's updated guide describes with flair and authority China's often tortuous, sometimes triumphant pursuit of "modernity", what it has meant for the Chinese people, and what we can expect it to mean in future - for all of us." Graham Hutchings, Oxford Analytica. "Now updated to bring the story of modern China up into the era of Xi Jinping, this slim, accessible, and lively volume offers an appealing mix of information and argument. The first edition proved popular with students as a classroom text, so I look forward to putting this 2.0 version to use in future courses." Jeff Wasserstrom, author of China in the 21st Century : What Everyone Needs to Know.
Crystallography
A long history -- Symmetry -- Crystal structures -- Diffraction -- Seeing atoms -- Sources of radiation
Savannas
Due to pressures on land for development, savannas are at the forefront of research and conservation concerns. Here, Peter A. Furley describes the range of ecosystems encompassed in the savanna landscape; their rich wildlife; their impact on humans and their evolution; and the approaches to their conservation and management.
Coral Reefs
Coral reefs are among the most biodiverse of ecosystems. Here, Charles Sheppard tells the fascinating story of how and where coral reefs are formed and the variety of marine life they support. He highlights the severe threats they face due to climate change, pollution, and over-exploitation, and the ongoing conservation efforts to save them.
