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Reducing Complexity: Explaining Inborn Errors of Metabolism and Their Treatment to Children and Adolescents
Abstract: Background Inborn errors of metabolism (IEM) are a group of rare, heterogeneous and complex genetic conditions. Clinically, IEM often affect the central nervous system and other organs. Some carry the risk of progression and / or potentially life-threatening crises. Many patients have to adhere to lifelong dietary or drug treatment. The complexity of IEM makes it difficult for patients and caregivers to understand their pathophysiology, inheritance and therapy rationale. Especially patients reaching adolescence may have only limited knowledge of their condition since medical care has often entirely been handled by their parents. Knowledge about disease and treatment, however, const...
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The Mountain
"The bear knows exactly what the mountain looks like a forest. The sheep, octopus, and ant also know the mountain. It's a meadow! It's surrounded by water...The chamois and snow hare have their opinions too. It seems the mountain looks different to every animal. How can that be? And whose point of view is right?"--
Big Picture Book How Food Grows
The Big Picture Book How Food Grows is full of beautiful illustrations of plants, grains and trees in different habitats, that will encourage children to explore outdoors and find out more about where their food comes from.
Kenzo Takada
* An exclusive look-book of hand-colored sketches and personal photographs from the archives of Japanese fashion designer Kenzo Takada* Includes hundreds of sketches and personal photographs which offer an insider's perspective on his career, creative process, and vision* Features a stunning cover design by KenzoIn 1970, the young Japanese designer Kenzo Takada opened his first boutique, Jungle Jap, in Paris and revolutionized the fashion world. His colorful, ethnic, and nomadic- influenced collections, made with luxurious and vibrantly patterned textiles, tweaked the conventions of haute couture while maintaining the quality of traditional European clothing houses. He was influenced by Pari...
Slave Trade and Abolition
Well into the early nineteenth century, Luanda, the administrative capital of Portuguese Angola, was one of the most influential ports for the transatlantic slave trade. Between 1801 and 1850, it served as the point of embarkation for more than 535,000 enslaved Africans. In the history of this diverse, wealthy city, the gendered dynamics of the merchant community have frequently been overlooked. Vanessa S. Oliveira traces how existing commercial networks adapted to changes in the Atlantic slave trade during the first half of the nineteenth century. Slave Trade and Abolition reveals how women known as donas (a term adapted from the title granted to noble and royal women in the Iberian Peninsula) were often important cultural brokers. Acting as intermediaries between foreign and local people, they held high socioeconomic status and even competed with the male merchants who controlled the trade. Oliveira provides rich evidence to explore the many ways this Luso-African community influenced its society. In doing so, she reveals an unexpectedly nuanced economy with regard to the dynamics of gender and authority.
The Weekend Away
***Now a Netflix Original movie, starring Leighton Meester, streaming globally.*** Miles from home. Trust no one. Suspect everyone.
Hygiene and the Assassin
Published in English for the first time, Nothomb's award-winning novel tells the story of a reclusive and dying Nobel laureate author who grants access to five journalists. But what they find is far from the literary luminary they imagined.
