Nina Raulf

NIR, an Inhibitor of Histone Acetyltransferases, Regulates Transcription Factor TAp63 and is Controlled by the Cell Cycle

• Author(s): Kristina Heyne, Vivienne Willnecker, Julia Schneider, Marcel Conrad, Nina Dorothea Raulf, Roland Schüle, Klaus Römer

• Type: Book
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• Published: 2010
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• Publisher: Unknown

Abstract: p63 is a sequence-specific transcription factor that regulates epithelial stem cell maintenance and epithelial differentiation. In addition, the TAp63 isoform with an N-terminal transactivation domain functions as an inducer of apoptosis during the development of sympathetic neurons. Previous work has indicated that the co-activator and histone acetyltransferase (HAT), p300, can bind to TAp63 and stimulate TAp63-dependent transcription of the p21Cip1 gene. Novel INHAT Repressor (NIR) is an inhibitor of HAT. Here, we report that the central portion of NIR binds to the transactivation domain and the C-terminal oligomerization domain of TAp63. NIR is highly expressed in G2/M phase of ...

Nina

• Author(s): Nina van Pallandt

• Type: Book
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• Published: 1970
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• Publisher: Unknown

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Nina and Vic

• Author(s): Joan Hannington, Nina Chessall, Vic Vinnell

• Type: Book
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• Published: 2004-11-01
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• Publisher: Unknown

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Nina

• Author(s): Luise Rinser

• Type: Book
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• Published: 1970
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• Publisher: Unknown

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Nina

• Author(s): Doris Cahill

• Categories: Donkeys

• Type: Book
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• Published: 2001-10-01
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• Publisher: Unknown

When Suzie's family moves to old Mexico for her dad's health, Niña the burro moves into their lives.