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This book provides an essential overview of the basic principles of imaging modalities, accompanied by examples of their applications in modern clinical and associated pre-clinical studies. The monograph is based on the original results of investigation of the efficiency use of laser light and Mueller-matrix polarimetry approach for assessment of myocardial tissues towards confirmation the cause of death. A morphological analysis of necrotic changes in the myocardial tissue of patients that died due to heart attack, coronary heart disease and acute coronary insufficiency was carried out and the data and histological sections of the myocardium inspected utilizing Mueller-matrix mapping of tis...
This book highlights the analysis of new azimuth-independent methods of Stokes polarimetry and Mueller-matrix reconstruction of distributions of optical anisotropy parameters using spatial-frequency filtering of manifestations of phase (linear and circular birefringence) and amplitude (linear and circular dichroism) anisotropy for diagnosing changes in the orientational-phase structure of fibrillar networks of histological sections of biological tissues and polycrystalline films of biological fluids.
This book presents experimental investigations and digital image processing, highlighting the interaction of polarized radiation with phase-inhomogeneous and optically anisotropic biological layers. The promising and efficient use of vector-parametric description of the formation of polarization-inhomogeneous object fields is noted. Applications of a set of Mueller-matrix polarimetry methods are highlighted. The book includes- structural and logical scheme of multi-parameter (singular, interference and layer-by-layer Stokes-polarimetric), polarization-correlation study of the structure of distributions of the number of singularities, maps of local contrast of interference distributions and layer-by-layer maps of microscopic polarization azimuth and ellipticity; determination of relationships between changes in the magnitude of statistical parameters characterizing polarization-correlation distributions and pathology of prostate tumors.
In continuation of the FRINGE Workshop Series this Proceeding contains all contributions presented at the 7. International Workshop on Advanced Optical Imaging and Metrology. The FRINGE Workshop Series is dedicated to the presentation, discussion and dissemination of recent results in Optical Imaging and Metrology. Topics of particular interest for the 7. Workshop are: - New methods and tools for the generation, acquisition, processing, and evaluation of data in Optical Imaging and Metrology (digital wavefront engineering, computational imaging, model-based reconstruction, compressed sensing, inverse problems solution) - Application-driven technologies in Optical Imaging and Metrology (high-...
This book highlights the effectiveness of differential diagnosis in the degree of severity of joint pathology from a clinical, biophysical, and informational point of view. It includes the following information blocks: • Two-dimensional digital polarization microscopy of polycrystalline films of synovial fluid and determination of the coordinate distributions of the orientation and phase parameters of the microscopic image from a set of parameters of the Stokes vector. • Mueller-matrix mapping of polycrystalline films of synovial fluid and determination of a set of coordinate distributions (Mueller-matrix images (MMI)) of azimuthal-invariant elements that characterize manifestations of o...
Optical Polarization in Biomedical Applications introduces key developments in optical polarization methods for quantitative studies of tissues, while presenting the theory of polarization transfer in a random medium as a basis for the quantitative description of polarized light interaction with tissues. This theory uses the modified transfer equation for Stokes parameters and predicts the polarization structure of multiple scattered optical fields. The backscattering polarization matrices (Jones matrix and Mueller matrix) important for noninvasive medical diagnostic are introduced. The text also describes a number of diagnostic techniques such as CW polarization imaging and spectroscopy, polarization microscopy and cytometry. As a new tool for medical diagnosis, optical coherent polarization tomography is analyzed. The monograph also covers a range of biomedical applications, among them cataract and glaucoma diagnostics, glucose sensing, and the detection of bacteria.
Despite a number of books on biophotonics imaging for medical diagnostics and therapy, the field still lacks a comprehensive imaging book that describes state-of-the-art biophotonics imaging approaches intensively developed in recent years. Addressing this shortfall, Advanced Biophotonics: Tissue Optical Sectioning presents contemporary methods and
This volume provides a comprehensive overview of the current issues facing scientists working on delivering drugs locally and systemically via the membranes that line the mouth. The book describes the anatomical and physiological challenges of this route for drug delivery and how they impact the design of oral mucosal drug delivery systems. It also provides a detailed description of current oral mucosal drug delivery technologies that overcome these challenges alongside research, development and assessment methods. In 11 authoritative chapters, the book affords an in-depth evaluation of the major issues associated with this route of administration, namely the retention of the drug/product at...
This book gathers the proceedings of the 4th International Conference on Nanotechnologies and Biomedical Engineering, held on September 18-21, 2019, in Chisinau, Republic of Moldova. It continues the tradition of the previous conference proceedings, thus reporting on both fundamental and applied research at the interface between nanotechnologies and biomedical engineering. Topics include: developments in bio-micro/nanotechnologies and devices; biomedical signal processing; biomedical imaging; biomaterials for biomedical applications; biomimetics; bioinformatics and e-health, and advances in a number of related areas. The book offers a timely snapshot of cutting-edge, multidisciplinary research and developments in the field of biomedical and nano-engineering.