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Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven, describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strategies to target and improve chemotherapy efficacy. Pumps of the ATP-binding cassette superfamily (ABCs) regulate the access of drugs to the intracellular space. In this context, the overexpression of ABCs is a well-known mechanism of multidrug resistance in cancer and is associated with therapeutic failure. Cancer types discussed include breast, endocrine, hematologic, gastrointestinal, musculoskel...
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Beginning with 1962, references are not limited to material in the English language.
The standard location tool for full-length plays published in collections and anthologies in England and the United States since the beginning of the 20th century, Ottemiller's Index to Plays in Collections has undergone seven previous editions, the latest in 1988, covering 1900 through 1985. In this new edition, Denise Montgomery has expanded the volume to include collections published in the entire English-speaking world through 2000 and beyond. This new volume lists more than 3,500 new plays and 2,000 new authors, as well as birth and/or death information for hundreds of authors. Representing the largest expansion between editions, this updated volume is a valuable resource for libraries worldwide.
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Includes entries for maps and atlases.