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Cancer stem cells have originally been identified in leukemia and later in several solid tumor types. They have very different properties from the bulk of the tumor as they divide much more slowly and have very efficient drug resistance mechanisms. Current treatments might largely spare cancer stem cells. This book looks at recent developments in the field of cancer stem cells and the possible impact for the identification of novel treatment paradigms for cancer.
A 35-year-old woman arrives on the labour ward complaining of abdominal pain and vaginal bleeding at 36 weeks 2 days' gestation. The pain started 2 hours earlier while she was in a cafe and is not relieved by lying still or walking around. The bleeding is bright red. You are the medic on duty... 100 Cases in Obstetrics and Gynaecology presents 100 obstetric- or gynaecology-related scenarios commonly seen by medical students and junior doctors in the emergency department, outpatient clinic, or on the ward. A succinct summary of the patient's history, examination, and initial investigations—including photographs where relevant—is followed by questions on the diagnosis and management of eac...
This fully revised directory of international foundations, trusts, charitable and grantmaking NGOs and other similar non-profit institutions provides a comprehensive picture of foundation activity on a worldwide scale. Now in its 32nd edition, The Europa International Foundation Directory includes: Information on some 2,700 organizations, organized by country or territory, including details of funding priorities and projects, geographical area of activity, principal staff and contact details Details of co-ordinating bodies and centres that assist foundations, grantmaking organizations and other NGOs Bibliography Comprehensive index section This new edition has been revised and expanded to include the most comprehensive and up-to-date information on this growing sector.
This volume brings together an interdisciplinary group of specialists to present and discuss the latest diagnostic and therapeutic concepts and current controversial issues in the management of primary and secondary brain tumors. In the first part, the latest technical developments in neuro-oncology are presented. These include the evaluation of positron-emission tomography for diagnosis, and neuronavigation and operative mapping for operation planning. Innovations in computer-assisted 3-D radiotherapy planning and in image fusioning of CT, MRT, SPECT and PET are also described. A large section of the book is devoted to the diagnosis and interdisciplinary treatment of glioblastoma, one of th...
Recent work in the mobilities literature has highlighted the importance of thinking about mobility and immobility as a continuum, where movement intersects with processes that might entail episodes of transition, waiting, emptiness, and fixity. This focus on stillness, things that are stuck, incomplete or in a state of transition can point to new theoretical, methodological and practical dimensions in social studies of medicine. This edited volume brings the concept of immobility to the forefront of social studies of medicine to explore how immobility shapes processes of medical care and the theoretical and methodological challenges of studying immobility in medical contexts. The authors in this volume draw from a wide range of case studies across the globe to make contributions to our current understanding of health, illness and medicine, mobilities and immobilities. Chapter 2 “Lists in Flux, Lives on Hold? Technologies of Waiting in Liver Transplant Medicine” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
The title of this monograph, Brain Tumor Research and Therapy, is the name of the Conference itself, which had its inaugural meeting in the United States in 1975 andhas since progressed to the international scale. In Japan, the first conference ofits kind was organized by Dr. Takao Hoshino and me and was held at Nikko in 1980, hence its name, the Nikko Conference on Brain Tumor Research and Therapy. Though it started as a small, closed meeting, the conference has grown considerably, and in 1992 it was reorganized as the Japanese Conference on Brain Tumor Research and Therapy and was opened to all neurosurgeons and neuropathologists interested in the study of brain tumor problems and who are participating in this field. The main purpose of the Conference on Brain Tumor Research and Therapy is the candid and informed discussion of the most up-to-date developments in basic re search and clinical treatment of brain tumors. The 3rd Japanese Conference on Brain Tumor Research and Therapy was held at Nasu (Tochigi Prefecture), Japan, in No vember 1994. It was a great honor to welcome many distinguished guests from over seas who kindly attended each session and made valuable contributions.
This volume covers the most important areas of glioblastoma – surgical resection, molecular pathology, targeted therapies, cancer stem cells, the role of DNA methylation, targeted sequencing for personalized therapy, animal models and advances in pediatric glioblastoma. Chapter authors are junior and senior investigators, who are well established in their particular areas and include neurosurgeons, neuropathologists, neurooncologists and basic scientists.
From Pulitzer Prize-winning and #1 New York Times bestselling author of The Emperor of All Maladies and The Gene, The Song of The Cell is the third book in this extraordinary writer's exploration of what it means to be human-rich with Siddhartha Mukherjee's revelatory and exhilarating stories of scientists, doctors, and all the patients whose lives may be saved by their work. In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth merchant, Antonie van Leeuwenhoek, look down their handmade microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences and altering bo...
This volume addresses the latest results of the Major Water Program of the Chinese Government which aims at the restoration of polluted water environments and sustainable management of water resources in China. It specifically summarizes the results of the BMBF-CLIENT project “Management of Water Resources in Urban Catchments” and the related MoST project “Key Technologies and Management Modes for the Water Environmental Rehabilitation of a Lake City from the Catchment Viewpoint” in Chaohu. The project is conducted by the Helmholtz-Centre for Environmental Research UFZ, Technische Universität Dresden, German and Chinese companies (WISUTEC, AMC, bbe Moldaenke, itwh, OpenGeoSys e.V., ...
Forget about your cancer for a moment and imagine your life without it. Now, ask yourself the question: does cancer have to consume my whole life? The answer lies dormant inside your mind and you urgently need to let it out, but you need help. Whether your hope is escaping the emotional pain, reducing the burden on your family, searching for remission, or just finding a new normal to cope peacefully, Cancer Survivorship: How to Navigate the Turbulent Journey is your roadmap. This step-by-step strategy to self-management teaches: · How to learn about your diagnosis and staging to help you make informed decisions about treatment choices · How to establish effective communication channels wit...