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Cancer Stem Cells
Cancer stem cells have originally been identified in leukemia and later in several solid tumor types. They have very different properties from the bulk of the tumor as they divide much more slowly and have very efficient drug resistance mechanisms. Current treatments might largely spare cancer stem cells. This book looks at recent developments in the field of cancer stem cells and the possible impact for the identification of novel treatment paradigms for cancer.
The Europa International Foundation Directory 2023
This fully revised directory of international foundations, trusts, charitable and grantmaking NGOs and other similar non-profit institutions provides a comprehensive picture of foundation activity on a worldwide scale. Now in its 32nd edition, The Europa International Foundation Directory includes: Information on some 2,700 organizations, organized by country or territory, including details of funding priorities and projects, geographical area of activity, principal staff and contact details Details of co-ordinating bodies and centres that assist foundations, grantmaking organizations and other NGOs Bibliography Comprehensive index section This new edition has been revised and expanded to include the most comprehensive and up-to-date information on this growing sector.
Advances in Biology and Treatment of Glioblastoma
This volume covers the most important areas of glioblastoma – surgical resection, molecular pathology, targeted therapies, cancer stem cells, the role of DNA methylation, targeted sequencing for personalized therapy, animal models and advances in pediatric glioblastoma. Chapter authors are junior and senior investigators, who are well established in their particular areas and include neurosurgeons, neuropathologists, neurooncologists and basic scientists.
Controversies in Neuro-oncology
This volume brings together an interdisciplinary group of specialists to present and discuss the latest diagnostic and therapeutic concepts and current controversial issues in the management of primary and secondary brain tumors. In the first part, the latest technical developments in neuro-oncology are presented. These include the evaluation of positron-emission tomography for diagnosis, and neuronavigation and operative mapping for operation planning. Innovations in computer-assisted 3-D radiotherapy planning and in image fusioning of CT, MRT, SPECT and PET are also described. A large section of the book is devoted to the diagnosis and interdisciplinary treatment of glioblastoma, one of th...
Immobility and Medicine
Recent work in the mobilities literature has highlighted the importance of thinking about mobility and immobility as a continuum, where movement intersects with processes that might entail episodes of transition, waiting, emptiness, and fixity. This focus on stillness, things that are stuck, incomplete or in a state of transition can point to new theoretical, methodological and practical dimensions in social studies of medicine. This edited volume brings the concept of immobility to the forefront of social studies of medicine to explore how immobility shapes processes of medical care and the theoretical and methodological challenges of studying immobility in medical contexts. The authors in this volume draw from a wide range of case studies across the globe to make contributions to our current understanding of health, illness and medicine, mobilities and immobilities. Chapter 2 “Lists in Flux, Lives on Hold? Technologies of Waiting in Liver Transplant Medicine” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Chinese Water Systems
This volume addresses the latest results of the Major Water Program of the Chinese Government which aims at the restoration of polluted water environments and sustainable management of water resources in China. It specifically summarizes the results of the BMBF-CLIENT project “Management of Water Resources in Urban Catchments” and the related MoST project “Key Technologies and Management Modes for the Water Environmental Rehabilitation of a Lake City from the Catchment Viewpoint” in Chaohu. The project is conducted by the Helmholtz-Centre for Environmental Research UFZ, Technische Universität Dresden, German and Chinese companies (WISUTEC, AMC, bbe Moldaenke, itwh, OpenGeoSys e.V., ...
NeuroPhytomedicine
Neurological disorders categorized as neurodegenerative, neuropsychiatric, and neurotraumatic impose a substantial health burden and cause a frail impact on life attributes. The use of synthetic drugs can have undesirable side effects, making neurotherapeutics challenging. Research on neuroprotection aiming for the utilization of safer natural compounds; phytochemicals specifically – is a cutting-edge approach. NeuroPhytomedicine intends to present readers with a wide-ranging and state-of-the-art appearance at the beneficial properties of phytochemicals on various neurological ailments. It additionally contains sections explaining: • Applications of phyto-nanotechnology in neurological ailments, • Phytoconstituents related deep learning and machine learning-based solutions for neurological disorders, • Epigenetic relevance pertaining to modulation by phytochemicals. The goal of NeuroPhytomedicine is to give readers a thorough and up-to-date look at how phytochemicals affect the brain and neurological illnesses in a way that is helpful for research scholars, academicians, scientists, neuroscientists, physicians, and researchers from the pharmaceutical industry.
The Song of the Cell
From Pulitzer Prize-winning and #1 New York Times bestselling author of The Emperor of All Maladies and The Gene, The Song of The Cell is the third book in this extraordinary writer's exploration of what it means to be human-rich with Siddhartha Mukherjee's revelatory and exhilarating stories of scientists, doctors, and all the patients whose lives may be saved by their work. In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth merchant, Antonie van Leeuwenhoek, look down their handmade microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences and altering bo...
Muscle Disease
Written by more than 60 international experts in the field, Muscle Disease embodies the explosion of new concepts and information on the pathology and genetics of muscle disease that has occurred in recent years. In order to accommodate the new complex principles involved, the book is organized around the motor unit and the inherited disorders, in particular, are centered on the ultrastructure and organelles within the muscle fiber. In this way, the wide spectrum of muscle diseases, ranging from neurogenic and inflammatory disorders to those involving defects in a single gene, can be expressed in a logical sequence. For example, disorders that principally involve specific organelles or parti...
Neurodegeneration
Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, α-synuclein and TDP-43) and in the extracellular compartments (e.g. β-amyloid and prion ...
