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Bio-fabrication of liver cancer stem cells and testing of gemcitabine
Aim: Cancer stem cells are cell populations that are essential in drug resistance and cancer metastasis. Some liver cancer cells exhibit the characteristics of cancer stem cells, and it is crucial to study the activities and interactions of drugs in these cells. Huh7 is a human liver cancer cell with stem cell biomarkers and is used with induced pluripotent stem cells to form various cancer organoids through encapsulation methods. Due to their ease of use without animal testing, bio-fabrication studies of cell-encapsulated models have gained importance in the pharmaceutical industry in recent years. This study aimed to biofabricate Huh7 human liver cancer stem cells by alginate encapsulation...
Feature interview with Dr. William C. CHO - “Clarivate 2023 Highly Cited Researcher”
This insightful interview article covers the Journal of Cancer Metastasis and Treatment’s special interview with Dr. William C. Cho, focusing on his career trajectory, research focus, and ambitious goals for the next five years in cancer research. Dr. Cho, recognized as a Highly Cited Researcher in 2023 by Clarivate, has a wide research spectrum, including cancer biomarkers, non-coding RNA, genomics, and bioinformatics. In the interview, he elaborates on how advancements in these areas contribute to cancer treatment, emphasizing their potential impact on personalized medicine and therapeutic strategies. Dr. Cho shares experiences, underscores the importance of interdisciplinary collaborations, and highlights upcoming trends in cancer research. The interview may offer some guidance and advice to early-career researchers, encouraging them to find their passion, broaden their horizons, and make meaningful contributions to the field of cancer research.
Dare to Disappoint
Growing up on the Aegean Coast, Ozge loved the sea and imagined a life of adventure while her parents and society demanded predictability. Her dad expected Ozge, like her sister, to become an engineer. She tried to hear her own voice over his and the religious and militaristic tensions of Turkey and the conflicts between secularism and fundamentalism. Could she be a scuba diver like Jacques Cousteau? A stage actress? Would it be possible to please everyone including herself? In her unpredictable and funny graphic memoir, Ozge recounts her story using inventive collages, weaving together images of the sea, politics, science, and friendship.
The Median Nerve
This atlas systematically reviews motor conduction studies of the median nerve, from pilot human studies in peripheral nerve conduction during the 1950s through to the most recent scientific evidence. Descriptions are provided of a wealth of motor nerve conduction techniques that were reproduced in the laboratory, including both the originally proposed methods and variants. The techniques are organized according to practical criteria for ease of reference. Attention is focused especially on those techniques which have shown higher sensitivity and specificity in the diagnosis of compressive mononeuropathies like carpal tunnel syndrome (CTS) and on the most widely accepted guidelines, recommen...
Clinical Examination of the Hand
This handbook brings together the basic elements of hand and upper limb cases, from examination to clinical diagnosis of various hand and upper limb related diseases. It improvises the examination skills of the reader with proficiency to arrive at a provisional diagnosis for the given hand surgery and related diseases. The chapters are presented with simple language, clinical pictures, tables and embedded videos for readers. Written by contributors across the globe, this book is useful for trainees, graduates, postgraduates, and fellows who intend to brush up on their basics and excel in hand surgery. Key Features • Focuses on examination of hand and upper limb cases. • Serves as an illustrated reference of clinical examination for trainees, graduates, post-graduates and fellows. • Uses high-quality operative videos to demonstrate the clinical examination of various diseases of the hand and upper limb.
Document Production in International Arbitration
Because document production can discover written evidence that would otherwise not be available, it is often the key to winning a case. However, document production proceedings can be a costly and time-consuming exercise, and arbitral awards in particular are often challenged on grounds that relate to document production orders. The task of balancing the conflicting interests of the parties in this context is a major responsibility of arbitral tribunals. This book's analysis focuses on whether there exist legal principles on which arbitrators should establish rules of document production in both civil law and common law countries, and shows how international arbitration is affected. The auth...
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
AO Manual of Fracture Management
In the last quarter century, no one has played a stronger role in hand and wrist fracture management, especially using AO principles, than Jesse Jupiter. This long awaited book is the culmination of his work, along with other pioneers in the field, and presents all key developments in biomechanics, design, materials, and state-of-the-art AO techniques. Organized in a case-based format, the book focuses on fractures of the hand, scaphoid, and distal radius (including soft-tissue injuries). For each case, you'll review patient history, planning, approach, reduction, fixation, and rehabilitation, along with hundreds of full-color illustrations, intraoperative pictures, and x-rays. Online access to videos demonstrating step-by-step intraoperative procedures is included with the book. Along with detailed surgical techniques, you'll also find a wealth of guidelines on indications, choice of surgical approach, preoperative planning, and postoperative management. This is a book no orthopedic surgeon should be without.
The Fire Never Goes Out
From ND Stevenson, the New York Times bestselling author-illustrator of Nimona, comes a captivating, honest illustrated memoir that finds him turning an important corner in his creative journey—and inviting readers along for the ride. In a collection of essays and personal mini-comics that span eight years of his young adult life, author-illustrator ND Stevenson charts the highs and lows of being a creative human in the world. Whether it’s hearing the wrong name called at his art school graduation ceremony or becoming a National Book Award finalist for his debut graphic novel, Nimona, ND captures the little and big moments that make up a real life, with a wit, wisdom, and vulnerability that are all his own. Named one of Bank Street College of Education's Best Children’s Books of the Year!
