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It would have been difficult at the beginning of the 80's to have predicted that by the end of the decade, Medical Virology would have become one of the most important topics in the area of both basic and clinical research. Although we were expecting a progressive increase in awareness of the role played by viruses in different diseases, we did not expect the outbreak of a fatal disease that was going to shake the roots of our society. The appearance of the human immunodeficiency virus (HIV-1) in the early 80's, has prompted a unique re search impetus in the area of Medical Virology. The knowledge that we are gaining in our attempt to understand the biology of HIV-1 and the immuno logical re...
A concise survey by physicians and researchers of the latest thinking about the causes of diabetes and the best approaches to treating its acute and chronic complications. The authors pay special attention to explaining the molecular basis of diabetes and its complications, as well as to the many recent developments in whole pancreas and islet cell transplantation, including the means for avoiding the rejection of transplanted islets.
This book outlines the underlying principles on which modern road lighting is based, and provides the reader with knowledge of how these principles should be applied in practice. This book offers a completely fresh approach to the subject, reflecting how the technology of road lighting has progressed to keep up with the changes in lamp technology, especially in solid state light sources, and the increasing awareness of energy use and environmental issues. The book is divided into three parts. Part One describes lighting of open roads, with chapters discussing visual performance and comfort (including the effects of mesopic vision and age), and international standards and recommendations for ...
The papers published herein comprise the presentations given at the eighteenth of an annual series of clinical symposia arranged under the auspices of the Eastern Pennsylvania Branch of the American Society for Microbiology. This symposium allowed approximately 200 persons to gather and exchange ideas on the rapid laboratory diagnosis of infectious diseases. The institution of the Diagnosis Related Group (DRG) method for reimbursement by both government agencies and private insurance carriers has provided a financial aspect to the established clinical reasons for rapid laboratory diagnosis. Now the health of the institution, as well as the patient, is dependent on a timely diagnosis and, hop...
The richer countries spend about US$165 billion yearly on overseas aid, mainly to keep human development going. These efforts are undermined by climate change, water-catchment damage, biodiversity loss, and desertification, and their interactions with social systems at all scales, which few aid designs or evaluations fully address. This must change if aid performance is to be improved. Constraints to be overcome include limited understanding of the very complex systems that aid investments affect, and of the ecology behind climate change adaptation and mitigation. Aid Performance and Climate Change targets these problems and others, by explaining how to use multiple points of view to describ...
The Natural History of Rabies, Volume I explores the fundamental aspects of the rabies virus, including its growth, latency, morphology, chemistry, physical characteristics, and relationships with other viruses. It looks at the virus' in vivo pathogenesis and pathology, from entrance to transmission in the central nervous system (CNS) and subsequent exit. It also reviews current diagnostic methods including those used for antibody titration and for determination of virus presence. Organized into three sections encompassing 21 chapters, this volume begins with an overview of the history of rabies as well as its morphology and morphogenesis. It then discusses the virus' antigenic composition a...
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Rapid progress in molecular biology, genetic engineering, and basic research in immunology has opened up new possibilities for application to diagnostic procedures and to clinical research. In a short period a new era of diagnosis dawned, covering nearly all fields of microbiology, immunology, and food technology. In consequence of this rapid development, scientists of many disciplines are involved studying infections of humans, animals, and plants or working in technical microbiology. The application of the newest findings of basic research to diagnostic work and to clinical research covers nearly all fields of microbiology and immunology. Moreover, it underlines the close relationship betw...
This book deals with the electronic and optical properties of two low-dimensional systems: quantum dots and quantum antidots and is divided into two parts. Part one is a self-contained monograph which describes in detail the theoretical and experimental background for exploration of electronic states of the quantum-confined systems. Starting from the single-electron picture of the system, the book describes various experimental methods that provide important information on these systems. Concentrating on many-electron systems, theoretical developments are described in detail and their experimental consequences are also discussed. The field has witnessed an almost explosive growth and some of...