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Practical Genomics for Clinical Ophthalmology provides in-depth coverage of the clinical applications of genomics in eye disease, with a key emphasis on case-study based instruction in patient care and genetic counseling aspects, genetic and genomic diagnostics, and treatment pathways. The book presents the latest information on genetic and genomic test results, best practices for delivery of results to patients and families, and ongoing research into therapeutics, with specific chapters covering non-syndromic inherited retinal disease, syndromic IRD, vitreoretinopathies, lens abnormalities, corneal disease, albinism, anterior segment dysgenesis, glaucoma, developmental eye abnormalities, ny...
New chapters, new editors and contributors make Taylor and Hoyt's Pediatric Ophthalmology and Strabismus, 5th Edition, the most current and complete reference available in this evolving field. Editors Scott R. Lambert and Christopher J. Lyons, both globally recognized leaders, provide authoritative coverage of all the pediatric ophthalmic conditions you’re likely to encounter in practice, including the latest clinical advances in etiology, diagnosis, and medical and surgical management. Expert guidance on the complete spectrum of childhood eye disorders and strabismus, including a unique "practical problems" section designed to help you handle difficult patient situations. More than 1,800 ...
This second volume continues with a focus on the state of the art in genetic eye research in Asia and the Pacific. Though there has been an explosion of information on genetic eye research in western countries, more than sixty percent of the human genes involved in eye diseases in the Asian and Pacific population remain unknown. However, new efforts and a new awareness have sparked important discussions on the subject, and new plans are being implemented to discover the genes responsible for many eye diseases in the population. The book reviews the latest findings; its content ranges from genetic aspects of human migration to DNA sequence analysis, genome-wide association analysis, and disea...
This lavishly illustrated atlas provides indispensable information to clinicians, geneticists and visual scientists working with inherited retinal diseases. It is filled with high-quality images, up-to-date genetic information and comprehensive electrophysiology. The data for each individual disorder have been summarised in an accessible, reader-friendly format for easy reference. The illustrations include colour fundus photographs, fluorescein angiograms, OCT scans, electrophysiological studies and pedigrees. The editors and authors are well-known experts in the field and have drawn upon their extensive experience to produce this unique atlas.
Providing foundational knowledge and expert guidance on the complete spectrum of childhood eye disorders and strabismus, Taylor and Hoyt's Pediatric Ophthalmology and Strabismus, 6th Edition, remains the #1 reference of choice for practicing and trainee pediatric ophthalmologists. Edited by global leaders in the field, Drs. Christopher J. Lyons and Scott R. Lambert, this newly revised volume offers authoritative coverage of all the pediatric ophthalmic conditions you're likely to encounter in practice, including the latest clinical advances in etiology, diagnosis, and medical and surgical management. Comprehensive updates, as well as new chapters, images, and video clips, make this well-rega...
This book constitutes the refereed proceedings of the 23rd Conference on Medical Image Understanding and Analysis, MIUA 2019, held in Liverpool, UK, in July 2019. The 43 full papers presented were carefully reviewed and selected from 70 submissions. There were organized in topical sections named: oncology and tumour imaging; lesion, wound and ulcer analysis; biostatistics; fetal imaging; enhancement and reconstruction; diagnosis, classification and treatment; vessel and nerve analysis; image registration; image segmentation; ophthalmic imaging; and posters.
Pediatric Ophthalmology and Strabismus is your one-stop source for comprehensive coverage of all the pediatric ophthalmic conditions you are likely to encounter in practice. Extensively updated with expert contributions from leaders in the field and now featuring online instructional videos, this ophthalmology reference delivers all the state-of-the-art guidance you need to effectively diagnose and manage even the most challenging eye diseases and disorders seen in children. Take a holistic approach to patient management that considers the family and ensures optimal doctor-patient relationships. Get a balanced view of etiology, diagnosis, and management, and access unique guidance on the pra...
This book presents the latest knowledge and expert guidance on all aspects of inherited retinal diseases, including molecular genetics, diagnosis, clinical features, general principles of treatment, novel treatment methods, and genetic counseling. Recent years have witnessed great advances in understanding of the genetic and cytological background of these diseases. Genetic analysis methods such as next generation sequencing have remarkably reduced the cost and time required for massive analysis of patients’ samples. Studies on gene therapy and stem cell therapy have been successfully carried out in animal models, and gene therapy is now available for Leber congenital amaurosis caused by RPE65 mutations. Against this background, Inherited Retinal Disease will be an invaluable up-to-date resource for ophthalmologists, medical students, and researchers in ocular inflammation. In addition to supplying essential information on each individual disorder, it features many interesting cases contributed by global leaders in the field as well as clinical photographs obtained with newer imaging techniques and numerous images of rare but clinically important diseases.
This book introduces Python as a powerful tool for the investigation of problems in computational biology, for novices and experienced programmers alike.