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In this thesis, I study three stochastic methods that can be applied for the analysis of data in cancer research and, in particular, to cancer genomic data and to images of angiogenic processes. Cancer is a multistep process where the accumulation of genomic lesions alters cell biology. The latter is under control of several pathways and thus, cancer can arise via different mechanisms affecting different pathways. Due to the general complexity of this disease and the different types of tumors, the efforts of cancer research cover several research areas such as, for example, immunology, genetics, cell biology, angiogenesis.
This book constitutes the thoroughly refereed post-conference proceedings of the 12th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2015, held in Naples, Italy, in September, 2015. The 21 revised full papers presented were carefully reviewed and selected from 24 submissions. They present problems concerning computational techniques in bioinformatics, systems biology and medical informatics discussing cutting edge methodologies and accelerate life science discoveries, as well as novel challenges with an high impact on molecular biology and translational medicine.
ECMI, the European Consortium for Mathematics in Industry, is the European brand associated with applied mathematics for industry and organizes highly successful biannual conferences. In this series, the ECMI 2010, the 16th European Conference on Mathematics for Industry, was held in the historic city hall of Wuppertal in Germany. It covered the mathematics of a wide range of applications and methods, from circuit and electromagnetic device simulation to model order reduction for chip design, uncertainties and stochastics, production, fluids, life and environmental sciences, and dedicated and versatile methods. These proceedings of ECMI 2010 emphasize mathematics as an innovation enabler for industry and business, and as an absolutely essential pre-requiste for Europe on its way to becoming the leading knowledge-based economy in the world.
This book constitutes the refereed proceedings of the 10th International Work-Conference on Artificial Neural Networks, IWANN 2009, held in Salamanca, Spain in June 2009. The 167 revised full papers presented together with 3 invited lectures were carefully reviewed and selected from over 230 submissions. The papers are organized in thematic sections on theoretical foundations and models; learning and adaptation; self-organizing networks, methods and applications; fuzzy systems; evolutionary computation and genetic algoritms; pattern recognition; formal languages in linguistics; agents and multi-agent on intelligent systems; brain-computer interfaces (bci); multiobjetive optimization; robotics; bioinformatics; biomedical applications; ambient assisted living (aal) and ambient intelligence (ai); other applications.
This volume (II) contains all publications accepted for the symposiums and workshops held in parallel with the 10th International Work-Conference on Artificial Neural Networks (IWANN 2009), covering a wide spectrum of technological areas such as distributed computing, artificial intelligence, bioinformatics, soft computing and ambient-assisted living: • DCAI 2009 (International Symposium on Distributed Computing and Artificial Intelligence), covering artificial intelligence and its applications in distributed environments, such as the Internet, electronic commerce, mobile communi- tions, wireless devices, distributed computing, and so on. This event accepted a total of 96 submissions selec...
Recent advances in biotechnology and the availability of ever more powerful computers have led to the formulation of increasingly complex models at all levels of life sciences, in particular of cardiac electrophysiology. Multiscale modeling of the bioelectric activity of the heart, taking into account macroscopic (fiber architecture and anisotropy) and microscopic (cellular) features of the tissue, aim to develop predictive tools for future drug design and patient-specific therapies, using detailed and efficient three-dimensional solvers for the governing equations of tissue electrophysiology.
The scientific area this thesis belongs to is many-valued logics: this meanslogics in which, from the semantical point of view, we have "intermediate"truth-values, between 0 and 1 (which in turns are designated to represent, respectively, the "false" and the "true").The classical logic (propositional, for simplicity) is based on the fact thatevery statement is true or false: this is reflected by the excluded middle law, that is a theorem of this logic. However, there are many reasons that suggestto reject this law: for example, intuitionistic logic does not satisfy it, sincethis logic reflects a "constructive" conception of mathematics (see [Hey71, Tro69]).