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The Alzheimer's Disease Challenge
Alzheimer’s disease is undoubtedly the major health challenge of our Century with significant social and economic consequences. This Frontiers eBook offers a contribution of 39 innovative papers on the multidimensional and crucial problem of Alzheimer’s disease management and treatment. Several perspectives, research updates, and trials describing methods on potential diagnosis and treatment are presented including biological mechanisms, biomarkers and risk factors for an early and efficient prognosis, diagnosis and prevention. Additionally, while the rapidly increasing Alzheimer’s disease population demands holistic solutions and clinical studies with new therapeutic target approaches, several of the contributive papers present promising drugs targeting Alzheimer’s disease treatment. We give our deepest acknowledgment to all the authors for their important and innovative contributions, to the reviewers for their valuable recommendations on improving the submitting studies and all the Frontiers Editorial team for continuous support.
The Role of Nutritional Strategies in the Regulation of Gut Microbiota and Host Immune System
The gut microbiota not only plays important roles in many metabolic pathways, but it also provides the host with a variety of functions that promote immune homeostasis, immune responses, and prevent pathogen colonization. The gut microbiota, as well as their metabolites and components, are required for immune homeostasis and influence host susceptibility to a wide range of immune-mediated diseases and disorders. The composition of the gut microbiota influences immune system development and modulates immune mediators, which in turn affects the function of the intestinal barrier. To this end, This Research Topic aims to present and discuss the most recent evidence on the role of nutritional strategies in regulating gut microbiota and host immune system, which will assist in understanding how nutritional strategies can promote immunity homeostasis and intestinal barrier function via the gut microbiota.
The Concubine of Shanghai
China, 1907. Sixteen-year-old orphan Cassia is sold by her aunt to a brothel. There, she works as a lowly maid for Madame Emerald until a powerful and dangerous client plucks her from obscurity. Master Chang is the boss of the fearsome Shanghai Triad and he always gets what he wants. Despite her unbound feet and breasts, Cassia swiftly becomes Chang's favourite mistress. He showers her with luxuries as he embarks on her sexual awakening. But Chang's world is violent and precarious, and those such as Cassia who depend on him are bound to his fate . . .
Translanguaging and the Bilingual Brain
Multilingual classrooms and online communication are becoming increasingly linguistically diverse due to globalization and new discourse patterns are emerging. Many of these patterns include the use of linguistic resources from multiple languages in the same utterance. Translanguaging, a recent theoretical framework, is gaining prominence among scholars interested in studying these multilingual discursive practices and the concept of a unitary language system for lexical processing. The aim of this book is to gain a better understanding of the bilingual brain and how words and sentences that use features from socially distinct languages are processed. Using examples provided by multilingual ...
