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Methods in Endothelial Cell Biology
Endothelial cell biology has developed into a vibrant discipline and has become a critical instrument to study several disease processes on the cellular and molecular level. It is now widely recognized that dysfunctions of normal endothelial cell homeostasis are involved in some of the most important human diseases, including ischemic heart diseases, hypertension, atherosclerosis, tumors, diabetes, arthritis, and inflammation. Further, the increasing importance and recognition of the field of vascular biology in general requires in vitro and in vivo techniques in order to address the complex questions. Methods in Endothelial Cell Biology is a comprehensive practical "how-to"-guide summarizing the most relevant established techniques as well as a number of new emerging techniques. Easy-to-follow reliable protocols provide a useful lab bench resource for the experienced researcher and newcomer to the field.
Spine Surgery
This book covers the content of European postgraduate spine surgery courses, using a case-based approach. It describes a stepwise solution to a real-world clinical problem and compares this with the best available evidence. It then provides suggestions on how to bridge the gap (if there is one) between standard of care and evidence-based medicine. Spine Surgery: A Case-Based Approach is aimed at postgraduate students of spine surgery (both trainee neurosurgeons and trainee orthopedic surgeons), and is also of interest to medical students.
Essentials of Spine Surgery
This concise textbook covers the full spectrum of spine surgery-related topics in a comprehensive yet easy-to-follow, readily accessible format. Addressing trauma, deformity, degeneration, oncology and infections, both in pediatric and adult patients, it provides a broad overview of this complex surgical discipline. Subdivided into four parts, each chapter exhaustively addresses a clinical problem, ranging from signs and symptoms, physical examination through differential diagnoses and classification to treatment options, possible complications and follow-ups. In appendix the reader will find relevant classifications, indexes, questionnaires and quality of life assessments. Didactical videos complement the book illustrating essential basic spine surgery techniques in the daily practice. Written by an international panel of experts this practical and handy guide is an invaluable tool for trainees of both orthopedic surgery and neurosurgery, spine fellows, and junior spine surgeons.
Cervical Spine Surgery: Standard and Advanced Techniques
This comprehensive, up-to-date textbook of modern cervical spine surgery describes the standard and advanced techniques recommended by the Cervical Spine Research Society – European Section (CSRS-E) with a view to enabling both young and experienced surgeons to further develop their skills and improve their surgical outcomes. Success in cervical spine surgery depends on the surgeon’s awareness of the main challenges posed by distinct cervical spine diseases, theoretical understanding of treatment concepts, and knowledge of technical options and the related potential for complications. It is the surgeon who has to merge theory and practice to achieve the desired outcome, in each case appr...
Surgical Techniques in Moyamoya Vasculopathy
A luminary in the field of cerebrovascular surgery brings his pace-setting work on the surgical management of moyamoya disease to the neurosurgical community When the rare stroke strikes in children and youth, a likely cause is the idiopathic disease moyamoya, characterized by the slow and progressive stenosis and occlusion of the internal carotid artery and the arteries of the circle of Willis. A result of these stenoses is the formation of collaterals that are typically small and fragile, and liable to rupture. While there is no cure for moyamoya, a variety of surgical procedures can be performed to re-establish and maintain adequate blood supply to the affected brain areas. The procedures...
Moyamoya Disease, 2nd edition
Moyamoya disease (MMD) is a chronic cerebrovascular disease characterized by progressive stenosis of the arteries of the circle of Willis, and formation of a collateral vascular network at the base of the brain. Moyamoya syndrome is caused by numerous conditions, which lead to arterial occlusion of the circle of Willis and resultant collaterals reminiscent of moyamoya disease. Due to the diverse angioarchitecture and unknown influence factors, the hemodynamic disturbances of MMD/Moyamoya syndrome are complicated, and result in multimodal clinical manifestations including headache, cognitive impairment, seizures, TIA, infarction, and hemorrhage. Surgical revascularization has been proven as e...
Bone Metastases
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Vascular Biology, Haemostasis and Extracellular Nucleic Acids in Vascular Diseases and Immunity. A Tribute to Klaus T. Preissner
Topic Editor Prof. Ritva Tikkanen Receives Research Funding From Neurogene Inc. and GC Pharma for Studies Unrelated to the Subject. Topic Editor Prof. Carl Blobel is Co-Inventor on a Patent Describing a Method of Identifying Agents for Combination With Inhibitors of iRhoms. He and the Hospital for Special Surgery (New York, USA) are Investigating Suitable Approaches to Identify iRhom Inhibitors, and are Co-Founders of a Small Company Called SciRhom in Munich to Pursue These Efforts. Topic Editor Dr. Sylvia Fischer Declares no Competing Interests With Regards to the Research Topic Subject.
Endonasal Endoscopic Surgery of Skull Base Tumors: An Interdisciplinary Approach
A comprehensive, multidisciplinary perspective on endonasal endoscopic skull base surgery This book presents a complete step-by-step guide to endonasal endoscopic skull base surgery, written by prominent interdisciplinary specialists and reflecting important recent developments in the field. Combining the fundamentals of skull base anatomy and pathology with current diagnostic and interventional imaging techniques, Endonasal Endoscopic Surgery of Skull Base Tumors provides a solid clinical foundation for anyone working in this challenging and evolving specialty. Special features: State-of-the-art contributions from international experts in endonasal endoscopic skull base surgery A 360 degree...
