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Methods in Endothelial Cell Biology
Endothelial cell biology has developed into a vibrant discipline and has become a critical instrument to study several disease processes on the cellular and molecular level. It is now widely recognized that dysfunctions of normal endothelial cell homeostasis are involved in some of the most important human diseases, including ischemic heart diseases, hypertension, atherosclerosis, tumors, diabetes, arthritis, and inflammation. Further, the increasing importance and recognition of the field of vascular biology in general requires in vitro and in vivo techniques in order to address the complex questions. Methods in Endothelial Cell Biology is a comprehensive practical "how-to"-guide summarizing the most relevant established techniques as well as a number of new emerging techniques. Easy-to-follow reliable protocols provide a useful lab bench resource for the experienced researcher and newcomer to the field.
Translational Research in Stroke
This book mainly discusses the current status of stroke transnational research and allows the reader to understand the interplay of common comorbidities in the stroke population such as diabetes and hypertension, and provides insight into stroke targets to promote cell survival, angiogenesis, neurogenesis, and most importantly, functional recovery after stroke. Throughout the world, stroke is still a leading cause of mortality and morbidity; each year approximately 15 million people worldwide suffer from stroke. Stroke is now the leading cause of death and disability in China. Large communities of stroke survivors are eagerly awaiting scientific advances in transnational stroke research that would offer neuroprotective therapeutics for acute stroke management, or rehabilitation and regenerative strategies utilizing novel stem cell-based approaches. While research is ongoing, the Editors have compiled this volume to help the further understanding of the pathophysiology of stroke and to review and identify future potential biomarkers. The book is written for students, researchers and physicians in neurosciences, neurology and neuroradiology.
My life - before and after the wall
When Emilie suddenly suffers a brain aneurysm during a skiing holiday, her husband Johan is brutally torn out of his previously comfortable life. This prompts him to review his past life, starting with his childhood on an "organic" farm and his career as an engineer in the GDR, to the fall of the Berlin Wall and what happened afterwards... Johan, alias "Blender", under which name the protagonist the Stasi, the East German secret police, has been a teetotaller, with many temptations in many places... In addition, the death-defying adventurer discovers his passion for mountaineering; he wants to conquer the highest peaks on earth, whatever the cost. But will he be able to defy the borderline experience of death?
Toward a New Culture of the Material
What happens when we begin treating multi-stable, ambivalent and adaptive behaviors of active matter as a formative principle? The contributions of this volume investigate the potential of the processual and untamable — ranging from microbial co-designing, morphogenetic experimentation and atmospheric creation to plasticity and liveliness in architecture, history of art and scientific concepts. Walking the line between analog and digital forms, the 19 perspectives from the Cluster of Excellence "Matters of Activity" not only cross disciplinary and methodological boundaries, but also aim at installing a new material paradigm between the epistemic cultures of sciences, humanities and design. Investigating a new culture of the material Interdisciplinary views on active structures, adaptive materials and sustainability
Essentials of Spine Surgery
This concise textbook covers the full spectrum of spine surgery-related topics in a comprehensive yet easy-to-follow, readily accessible format. Addressing trauma, deformity, degeneration, oncology and infections, both in pediatric and adult patients, it provides a broad overview of this complex surgical discipline. Subdivided into four parts, each chapter exhaustively addresses a clinical problem, ranging from signs and symptoms, physical examination through differential diagnoses and classification to treatment options, possible complications and follow-ups. In appendix the reader will find relevant classifications, indexes, questionnaires and quality of life assessments. Didactical videos complement the book illustrating essential basic spine surgery techniques in the daily practice. Written by an international panel of experts this practical and handy guide is an invaluable tool for trainees of both orthopedic surgery and neurosurgery, spine fellows, and junior spine surgeons.
Vascular Biology, Haemostasis and Extracellular Nucleic Acids in Vascular Diseases and Immunity. A Tribute to Klaus T. Preissner
Topic Editor Prof. Ritva Tikkanen Receives Research Funding From Neurogene Inc. and GC Pharma for Studies Unrelated to the Subject. Topic Editor Prof. Carl Blobel is Co-Inventor on a Patent Describing a Method of Identifying Agents for Combination With Inhibitors of iRhoms. He and the Hospital for Special Surgery (New York, USA) are Investigating Suitable Approaches to Identify iRhom Inhibitors, and are Co-Founders of a Small Company Called SciRhom in Munich to Pursue These Efforts. Topic Editor Dr. Sylvia Fischer Declares no Competing Interests With Regards to the Research Topic Subject.
Cervical Spine Surgery: Standard and Advanced Techniques
This comprehensive, up-to-date textbook of modern cervical spine surgery describes the standard and advanced techniques recommended by the Cervical Spine Research Society – European Section (CSRS-E) with a view to enabling both young and experienced surgeons to further develop their skills and improve their surgical outcomes. Success in cervical spine surgery depends on the surgeon’s awareness of the main challenges posed by distinct cervical spine diseases, theoretical understanding of treatment concepts, and knowledge of technical options and the related potential for complications. It is the surgeon who has to merge theory and practice to achieve the desired outcome, in each case appr...
The Oxford Handbook of Transcranial Stimulation
Transcranial stimulation encompasses noninvasive methods that transmit physical fields-such as magnetic, electric, ultrasound, and light-to the brain to modulate its function. The most widespread approach, transcranial magnetic stimulation (TMS), has emerged as an important tool in several areas of neuroscience as well as in clinical applications in psychiatry and neurology. Originally envisioned as a way to measure the responsiveness and conduction speed of neurons and synapses in the brain and spinal cord, TMS has also become an important tool for changing the activity of brain neurons and the functions they subserve as well as an causal adjunct to brain imaging and mapping techniques. Alo...
