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This report presents the recommendations of the WHO Expert Committee responsible for updating the WHO Model Lists of Essential Medicines. It contains a summary of the Committee's considerations and justifications for additions and changes to the Model Lists, including its recommendations. Annexes to the main report include the revised version of the WHO Model List of Essential Medicines (20th edition) and the WHO Model List of Essential Medicines for Children (6th edition). In addition there is a list of all the items on the Model Lists sorted according to their Anatomical Therapeutic Chemical (ATC) classification codes.
This report presents the recommendations of the WHO Expert Committee responsible for updating the WHO Model List of Essential Medicines. The first part contains a progress report on the new procedures for updating the Model List and the development of the WHO Essential Medicines Library. It continues with a section on changes made in revising the Model List followed by a review of some sections such as hypertensive medicines and fast track procedures for deleting items. Annexes include the 13th version of the Model List and items on the list sorted according to their 5-level Anatomical Therapeutic Chemical classification codes.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research...
This important book provides a comprehensive account of the advances that have occurred in fire science in relation to a broad range of materials. The manufacture of fire retardant materials is an active area of research, the understanding of which can improve safety as well as the marketability of a product. The first part of the book reviews the advances that have occurred in improving the fire retardancy of specific materials, ranging from developments in phosphorus and halogen-free flame retardants to the use of nanocomposites as novel flame retardant systems. Key environmental issues are also addressed. The second group of chapters examines fire testing issues and regulations. A final g...
The difficulties in determining the quality of information on the Internet--in particular, the implications of wide access and questionable credibility for youth and learning. Today we have access to an almost inconceivably vast amount of information, from sources that are increasingly portable, accessible, and interactive. The Internet and the explosion of digital media content have made more information available from more sources to more people than at any other time in human history. This brings an infinite number of opportunities for learning, social connection, and entertainment. But at the same time, the origin of information, its quality, and its veracity are often difficult to asses...
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This book gathers the proceedings of the 6th International Conference and Exhibition on Sustainable Energy and Advanced Materials (ICE-SEAM 2019), held on 16–17 October 2019 in Surakarta, Indonesia. It focuses on two relatively broad areas – advanced materials and sustainable energy – and a diverse range of subtopics: Advanced Materials and Related Technologies: Liquid Crystals, Semiconductors, Superconductors, Optics, Lasers, Sensors, Mesoporous Materials, Nanomaterials, Smart Ferrous Materials, Amorphous Materials, Crystalline Materials, Biomaterials, Metamaterials, Composites, Polymers, Design, Analysis, Development, Manufacturing, Processing and Testing for Advanced Materials. Sustainable Energy and Related Technologies: Energy Management, Storage, Conservation, Industrial Energy Efficiency, Energy-Efficient Buildings, Energy-Efficient Traffic Systems, Energy Distribution, Energy Modeling, Hybrid and Integrated Energy Systems, Fossil Energy, Nuclear Energy, Bioenergy, Biogas, Biomass Geothermal Power, Non-Fossil Energies, Wind Energy, Hydropower, Solar Photovoltaic, Fuel Cells, Electrification, and Electrical Power Systems and Controls.
Architecture and the arts have long been on the forefront of socio-spatial struggles, in which equality, access, representation and expression are at stake in our cities, communities and everyday lives. Feminist spatial practices contribute substantially to new forms of activism, expanding dialogues, engaging materialisms, transforming pedagogies, and projecting alternatives. 'Feminist Futures of Spatial Practice' traces practical tools and theoretical dimensions, as well as temporalities, emergence, histories, events, durations ? and futures ? of feminist practices. 0Authors include international practitioners, researchers, and educators, from architecture, the arts, art history, curating, cultural heritage studies, environmental sciences, futures studies, film, visual communication, design and design theory, queer, intersectional and gender studies, political sciences, sociology, and urban planning. Established as well as emerging voices write critically from within their institutions, professions, and their activist, political and personal practices.
The Republican Alternative seeks to move beyond the mere notion of scholarly inquiry into the republic—the subject of recent rediscovery by political historians interested in Europe’s intellectual heritage—by investigating the practical similarities and differences between two early modern republics, as well as their self-images and interactions during the turbulent seventeenth and eighteenth centuries. Among the world’s most economically successful societies, Switzerland and the Netherlands laid much of the foundation for their prosperity during the early modern period discussed here. This volume attempts to clarify the special character of these two countries as they developed, including issues of religious plurality, the republican form of government, and an increasingly commercially-driven agrarian society.