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In the last 10 years, the use of clinical exercise testing in respiratory medicine has grown significantly and, if used in the appropriate context, it has been demonstrated to provide clinically useful and relevant information. However, as its implementation and interpretation can be complicated, it should be used alongside previous medical evaluation (including medical history, physical examination and other appropriate complementary tests) and should be interpreted with the results of these additional tests in mind. This timely ERS Monograph aims to provide a comprehensive update on the contemporary uses of exercise testing to answer clinically relevant questions in respiratory medicine. The book covers: equipment and measurements; exercise testing in adults and children; cardiac diseases; interstitial lung disease; pulmonary vascular disease; chronic obstructive pulmonary disease; pre-surgical testing; and much more.
The traditional end-points for clinical studies of lung diseases were based on functional parameters. Their value as surrogate markers for disease activity and progression has been increasingly questioned by scientists, carers, regulatory agencies and funding bodies. Novel tools and methods with regard to biomarkers and patient-reported outcomes have made these parameters emerge from their status as interesting secondary end-points and become potential primary outcomes for clinical trials. Nevertheless, their relevance and validity still needs to be proven. This issue of the European Respiratory Monograph describes the current status regarding end-points in all relevant areas of pulmonary medicine.
This open access book studies breath and breathing in literature and culture and provides crucial insights into the history of medicine, health and the emotions, the foundations of beliefs concerning body, spirit and world, the connections between breath and creativity and the phenomenology of breath and breathlessness. Contributions span the classical, medieval, early modern, Romantic, Victorian, modern and contemporary periods, drawing on medical writings, philosophy, theology and the visual arts as well as on literary, historical and cultural studies. The collection illustrates the complex significance and symbolic power of breath and breathlessness across time: breath is written deeply into ideas of nature, spirituality, emotion, creativity and being, and is inextricable from notions of consciousness, spirit, inspiration, voice, feeling, freedom and movement. The volume also demonstrates the long-standing connections between breath and place, politics and aesthetics, illuminating both contrasts and continuities.
This Monograph provides the clinician with an up-to-date summary of the substantial evidence in our understanding of pleural disease. It covers key aspects relevant to clinicians, including mechanisms, pathophysiology, epidemiology, diagnostics, relevant experimental models and interventions. Although broad in scope, readers will be able to reach into individual chapters to gain a focused summary of specific areas relevant to their clinical or scientific practice.
This issue of Clinics in Chest Medicine, edited by Dr. Denis O'Donnell and Dr. Alberto Neder, focuses on Clinical Respiratory Physiology. Articles include: The Pathophysiology of Obstructive Sleep Apnea; The Physiology of Mechanical Ventilation; Exercise Pathophysiology in Congestive Heart Failure; Control of Breathing; Breathing at Extremes; Exercise Pathophysiology in Interstitial Lung Disease; Importance of Physiology in Clinical Decision-Making in the ICU; Pulmonary Hypertension and Exercise; Physiologic Effects of Oxygen Supplementation During Exercise in COPD; Benefits and Pitfalls of DLCO measurements in Clinical Practice; Cardio-pulmonary Interactions in COPD-CHF; Exercise Physiology in COPD; Dyspnea of Unknown Origin: The Role of Exercise Testing; Assessment of Ventilatory Limitation During Exercise; Respiratory Muscle Assessment in Clinical Practice; Exertional Periodic Breathing in Heart Failure; and Strategies to Increase Physical Activity in Chronic Respiratory Diseases
This book offers a state-of-the-art description of the complexity of the healthy and pathological respiratory system, with particular reference to the mechanics of the airways, lung and chest wall. Detailed information is provided on new insights into the mechanics of breathing that have been obtained through technological innovations in measurement systems, cutting-edge modeling techniques and novel approaches to functional imaging of the respiratory system. It is explained how these advances permit the assessment of emerging treatment approaches, including new drugs, innovative surgical techniques and modes of mechanical ventilation and new forms of rehabilitation. In order to ensure compr...
Chronic obstructive pulmonary disease (COPD) affects millions of people across the world. COPD is not only a major burden to patients but is also costly and results in billions of dollars of direct and indirect costs annually. In recent years and with advancement of science, the understanding of COPD has improved significantly. Fortunately, current management guidelines consider COPD a preventable and treatable condition, and recent studies clearly indicate that available pharmacological and non-pharmacological interventions may improve various clinical outcomes. COPD: A Guide to Diagnosis and Clinical Management offers an exciting, evidence-based assessment of the field and will be of signi...
The European Respiratory Society (ERS) Handbook of Respiratory Medicine, now in its third edition, is a concise, compact and easy-to-read guide to each of the key areas in respiratory medicine. Its 20 sections, written by clinicians and researchers at the forefront of the field, explain the structure and function of the respiratory system, its disorders and how to treat them. The Handbook is a must-have for anyone who intends to remain up to date in the field, and to have within arm's reach a reference that covers everything from the basics to the latest developments in respiratory medicine.
This Monograph provides a comprehensive overview of tobacco cessation, from health policy to patient care. Broad in scope, this state-of-the art collection is broken down into four sections: the changing landscape of the tobacco epidemic and challenges to curb it; treatment of tobacco dependence (pharmacotherapy, behavioural support); improving the care of patients with particular conditions who smoke (asthma, COPD, TB, cardiovascular diseases, etc.); and prevention. It also deals with some of the more controversial topics such as e-cigarettes and web applications. Readers will gain an understanding of how to implement smoking cessation into their everyday practice, but will also expand their knowledge about the policy and systems changes needed for population-wide smoking cessation.