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We are delighted to present the inaugural Frontiers in Oncology "Women in Cancer Imaging and Image-directed Interventions” series of article collections. At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and STEM research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.
The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
This book is intended for physicians and scientists with interest in glioblastoma biology, imaging and therapy. Select topics in DNA repair are presented here to demonstrate novel paradigms as they relate to therapeutic strategies. The book should serve as a supplementary text in courses and seminars as well as a general reference.
This volume constitutes the refereed proceedings of the 14th International Workshop on Combinatorial Image Analysis, IWCIA 2011, held in Madrid, Spain, in May 2011. The 25 revised full papers and 13 poster papers presented together with 4 invited contributions were carefully reviewed and selected from 60 submissions. The papers are organized in topical sections such as combinatorial problems in the discrete plane and space related to image analysis; lattice polygons and polytopes; discrete/combinatorial geometry and topology and their use in image analysis; digital geometry of curves and surfaces; tilings and patterns; combinatorial pattern matching; image representation, segmentation, grouping, and reconstruction; methods for image compression; discrete tomography; applications of integer programming, linear programming, and computational geometry to problems of image analysis; parallel architectures and algorithms for image analysis; fuzzy and stochastic image analysis; grammars and models for image or scene analysis and recognition, cellular automata; mathematical morphology and its applications to image analysis; applications in medical imaging, biometrics, and others.
Synaptic transmission demands the operation of a highly specialized metabolic machinery involving the transfer of metabolites and neurotransmitters between neurons, astrocytes and microvessels. In the last years, important advances have occurred in our understanding of the mechanisms underlying cerebral activation, neuroglial coupling and the associated neurovascular response. Briefly, exacerbated oxygen consumption in stimulated neurons is thought to trigger glycolytic lactate and glucose transfer from astrocytes which, in turn, obtain these fuels from the microvasculature. Neurotransmitter release is made possible by a combination of transcellular cycles exchanging metabolites between thes...
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