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AACR 2022 Proceedings: Part B April 11-13
The AACR Annual Meeting is the focal point of the cancer research community, where scientists, clinicians, other health care professionals, survivors, patients, and advocates gather to share the latest advances in cancer science and medicine. From population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy; the AACR Annual Meeting highlights the work of the best minds in cancer research from institutions all over the world.
Inflammation and Cancer
This second edition volume expands on the previous edition with an update on the broad spectrum of research models, techniques, and protocols used in laboratories by basic and clinical researchers. The chapters in this book are divided into two parts. Part One discusses the latest findings on the development and characterization of representative research models for chronic immune-based diseases and inflammation-associated cancers. Part Two covers biochemical, molecular, and cellular biological techniques that are commonly used to dissect the molecular mechanisms and cellular processes that drive the pathogenesis of certain disease states. Written in the highly successful Methods in Molecula...
Plant Foods of Greece
"Greek archaeologist Soultana Maria Valamoti takes readers on a culinary journey in her synthesis of plant foods and culinary practices of Neolithic and Bronze Age Greece. Plant foods were the main ingredients of daily meals in prehistoric Greece and most likely of special dishes prepared for feasts and rituals. For more than thirty years, Valamoti has been analyzing a large body of archaeobotanic data that spans 7,000 years from the Neolithic to Bronze Age and that was retrieved from nearly one hundred sites in mainland Greece and the Greek islands. This book also reflects experimentation and research of ancient written sources. Her approach allows an exploration of culinary variability thr...
Circulating Molecular Biomarkers: Next-Generation Tools for Monitoring Minimal Residual Disease in Cancer Patients
Traditional cancer diagnosis relies on tissue biopsy, blood testing as well as medical imaging. By the detection moment, in most cases the tumor size may reach several millimeters and the risk of distant metastasis is unavoidable. Even, following drug treatment, there is no accurate and timely way to follow up the success of treatment. New reliable tumor-specific biomarkers/tools that allow non-invasive early cancer detection as well as monitoring of anti-cancer therapeutic regime is highly demanded. To tackle limitations of traditional cancer management, liquid biopsy has emerged which screen bodily fluids using ultrasensitive biosensing systems capable of simultaneous capturing and studying horizontal gene transfer (HGT) materials including circulating tumor cells (CTCs), exosomes, cell-free DNA, and apoptotic bodies. These are messengers and/or delivery systems by which tumor cells are communicating as well as transforming/sharing new phenotypes with each other resulting in drug resistance, distant metastatic outbreaks, and cancer recurrence. Acting as next-generation prognostic and therapeutic tools call for understanding the molecular mechanisms by which HGT works to tran
Die kosmische Krise
Im Juni 2021 gesteht der Direktor der amerikanischen Geheimdienste unter gewaltigem Medieninteresse ein, dass unbekannte Luftphänomene (UAP), besser bekannt als UFOs, wirklich existieren. Kurz darauf verabschiedet der US-Kongress ein Gesetz, das vorsieht, eine speziell eingerichtete Behörde des Pentagons für deren Erforschung zu gründen. Das All-domain Anomaly Resolution Office solle nun endgültig klären, woher die unbekannten Objekte stammen und was sie beabsichtigen. Nach Jahrzehnten der Geheimhaltung bahnt sich damit eine politische und wissenschaftliche Sensation an. Wie aber konnte es dazu kommen? Die kosmische Krise erzählt die Geschichte unbekannter Luftphänomene und geht der Frage nach, ob wir allein sind im Universum. Dabei zeigt Gerritzen, dass die Euphorie über den möglichen Besuch außerirdischer Intelligenzen eine dramatische Kehrseite hätte: Wir sind gesellschaftlich nicht im Geringsten auf einen baldigen Erstkontakt vorbereitet. Sollte sich herausstellen, dass UAPs außerirdische Technologien sind, die uns beobachten, stünde die Menschheit angesichts urzeitlicher Ängste vor allem Fremden und Unbekannten vor einer wahrhaft kosmischen Krise.
Madness and Literature
Mental illness has been a favourite topic for authors throughout the history of literature, while psychologists and psychiatrists such as Sigmund Freud and Karl Jaspers have in turn been interested in and influenced by literature. Pioneers within philosophy, psychiatry and literature share the endeavour to explore and explain the human mind and behaviour, including what a society deems as being outside perceived normality. Using a theoretical approach that is eclectic and transdisciplinary, this volume engages with literature’s multifarious ways of probing minds and bodies in a state of mental ill health. The cases and the theory are in dialogue with a clinical approach, addressing issues ...
Sukcynit Skamieniała żywica odkryta na nowo
Bursztyn to skamieniała żywica roślinna pochodząca sprzed milionów lat, mieszanka związków organicznych i nieorganicznych. Można ją sklasyfikować jako mineraloid, czyli substancję naturalną o uporządkowaniu odmiennym niż minerały. Zawiera grupy różnych pierwiastków i mieszanin związków chemicznych. Do mineraloidów zaliczyć można perły, gagat, obsydian, opal. Bursztyn bałtycki, określany również jako sukcynit, powstał prawdopodobnie w wyniku uszkodzenia drzew, w następstwie czego wyciekała żywica zawierająca związki chroniące strukturę drzewa. Jedna z koncepcji zakłada, że żywica to produkt pochodzenia roślinnego, wytwarzany przez rosnące gatunki drzew...
Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants
Medicinal and aromatic plants are beneficial to human health. Plant-derived molecules possess biological activities that can be used to prevent many infectious diseases and metabolic disorders. Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants summarizes techniques and methods used to study the biological activities of plant-derived extracts and compounds to study ethnobotanical and ethnopharmacological features of medicinal and aromatic plants. This book: Includes computational approaches to study the pharmacological properties of biomolecules in medicinal and aromatic plants. Details methods in ethnopharmacology including chromatographical and analytical techniques. Demons...
