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This volume on drug metabolism covers the contribution that transgenic animal research, UDP-glucuronosyltransferases, CNS penetration advances and anticancer drugs can make to the subject.
The English botanist William Burchell arrived in Cape Town in June 1811 to explore the flora and fauna of the vast southern African interior. Over a four-year period, and travelling in a custom-built ox wagon, he amassed an astonishing 63 000 specimens of plants, bulbs, insects, reptiles and mammals – many not previously documented for science – as well as over 500 paintings and illustrations. While the outbound trek is well described in Burchell’s famous Travels in the Interior of Southern Africa, little has been published about the challenges and discoveries made on his return journey to Cape Town, from 1812–1815. This pioneering book traces the homeward leg of Burchell’s epic od...
Comprehensive Nuclear Materials, Five Volume Set discusses the major classes of materials suitable for usage in nuclear fission, fusion reactors and high power accelerators, and for diverse functions in fuels, cladding, moderator and control materials, structural, functional, and waste materials. The work addresses the full panorama of contemporary international research in nuclear materials, from Actinides to Zirconium alloys, from the worlds' leading scientists and engineers. Critically reviews the major classes and functions of materials, supporting the selection, assessment, validation and engineering of materials in extreme nuclear environment Fully integrated with F-elements.net, a proprietary database containing useful cross-referenced property data on the lanthanides and actinides Details contemporary developments in numerical simulation, modelling, experimentation, and computational analysis, for effective implementation in labs and plants
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In 1992, the Falk Symposium No. 70 dealt with the topic `Immunology and Liver'. At that time basic mechanisms of immunology as well as immunopathogenetic mechanisms in viral and autoimmune liver diseases were discussed. Now, 7 years later, the Falk Symposium No. 114, held in Basel, Switzerland, October 20-21 1999 (Part I of the Basel Liver Week 1999), focused on immunology in autoimmune liver diseases. In the first section basic mechanisms of autoimmunity are presented, including the relevance of superantigens and the role of apoptosis. A further topic is the latest developments concerning animal models for autoimmune diseases. Recently the International Autoimmune Hepatitis Group newly defi...