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Cell Death and Diseases of the Nervous System
It is an honor to be asked to write a foreword for this timely book, which assembles contributions from authorities working in the area of pathological nervous system cell death, and has been expertly edited by Vassilis Koliatsos and Rajiv Ratan. That the inap propriate demise of brain or spinal cord cells is at the root of many neurological diseases has been appreciated since the early days of microscopic neuropathology, but it has only been in the last decade or so that pervasive therapeutic nihilism has lifted. In the journey of medical progress, we have reached the shores of a marvelous new land. Three major scientific thrusts in particular have converged to produce the press of ideas co...
Glutathione In The Nervous System
The goal of this text is to focus readers attention on three major areas; the origin and localization of GSH in the nervous system; the multiple effects of GSH on neural health activity; and the potential for alterations on GSH status to lead to neurological damage of the type observed in amyotrophic lateral sclerosis, Parkinson's disease and other neurological disorders. The text also touches upon the additional roles of the antoxidant GSH, including possible neurotransmitter action, redox modulation of ionotropic receptor function, and neuroprotection against exicitoxic actions of glutamate.
Redox Cell Biology and Genetics, Part A
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today truly an essential publication for researchers in all fields of life sciences. Key Features * Cellular Responses * Tissues and Organs
Hypoxia
The latest in a series of books from the International Hypoxia Symposia, this volume spans reviews on key topics in hypoxia, and abstracts from poster and oral presentations. The biannual International Hypoxia Symposia are dedicated to hosting the best basic scientific and clinical minds to focus on the integrative and translational biology of hypoxia. Long before ‘translational medicine’ was a catchphrase, the founders of the International Hypoxia Symposia brought together basic scientists, clinicians and physiologists to live, eat, ski, innovate and collaborate in the Canadian Rockies. This collection of reviews and abstracts is divided into six sections, each covering new and important work relevant to a broad range of researchers interested in how humans adjust to hypoxia, whether on the top of Mt. Everest or in the pulmonary or cardiology clinic at low altitude. The sections include: Epigenetic Variations in Hypoxia High Altitude Adaptation Hypoxia and Sleep Hypoxia and the Brain Molecular Oxygen Sensing Physiological Responses to Hypoxia
Physical Medicine and Rehabilitation Secrets
For more than 30 years, the highly regarded Secrets Series® has provided students, academics, and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Physical Medicine and Rehabilitation Secrets, 4th Edition, offers practical, up-to-date coverage of the full range of essential topics in this dynamic field. This highly regarded resource features the Secrets’ popular question-and-answer format that also includes lists, tables, weblinks, pearls, memory aids, and an easy-to-read style – making an inquiry, reference, and review quick, easy, and enjoyable. The proven Secrets Series® format gives you the most return for ...
Apoptosis
Apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a process essential for normal health. This book, with contributions from experts in the field, provides a timely compilation of reviews of mechanisms of apoptosis. The book is organized into three convenient sections. The first section explores the different processes of cell death and how they relate to one another. The second section focuses on organ-specific apoptosis-related diseases. The third section explores cell death in non-mammalian organisms, such as plants. This comprehensive text is a must-read for all researchers and scholars interested in apoptosis.
A Gut Feeling
We all know sugar is bad for us, so why can’t we stop eating it? A Gut Feeling gives a personal and scientific look into the world of microbes that live within our bodies and how they can explain our relationship to and cravings for certain foods. Heather Wise takes the reader through a hidden inner world of microflora that shapes our mood, physical health, sweet cravings, and even genes. She makes us question whether a diet high in sugary, processed, dead foods—devoid of any microscopic life—may be causing us to feel sick, tired and depressed. The microbiome is emerging as the answer to many of our most sought after questions. Using her own story and the science currently available, Wise provides a window into the latest research on the vast world of microbes in our bodies. She explains in simple terms how what we eat can change the expression of our genes and how this symbiotic relationship between microbes and human cells can determine our health. This understanding sheds light on the fact that the gen
HyperHealing
Did your child just join the millions diagnosed with ADHD? (Why are there so many?) Do you KNOW your child is healthy but wish you had more tools (other than stimulant drugs) to help her succeed? Do you find yourself frequently exploding with frustration at your challenging child? In this entertaining and easy to read how-to guide, Avigail Gimpel, mother of six, special educator, college lecturer and parenting specialist will: • Confirm that your child is indeed healthy, and help you untangle the ADHD diagnosis. • Present a complete, clear, step-by-step intervention system to turn you into a ninja parent and get your struggling child back on track. • Explore how scientific research is used to justify medication. • Embrace you in the warmth of the HyperHealing community, an educational and support network for all parents of struggling children. HyperHealing is your complete ADHD coaching program and parenting guide in one book.
Neurobiology of Disease
Neurobiology of Disease is aimed at any basic scientist or clinician scientist teaching a course or conducting research on the basic science underlying the major neurological diseases. It provides an excellent overview of cutting-edge research on the fundamental disorders of the nervous system, including physiological and molecular aspects of dysfunction. The major categories of neurological disease are covered, and the chapters provide specific information about particular diseases exemplifying each of these categories. Sufficient clinical information is included to put into perspective the basic mechanisms discussed. The book assembles a world-class team of section editors and chapters written by acknowledged experts in their respective fields. Provides cutting edge information about fundamental mechanisms underlying neurological diseases Amply supplied with tables, illustrations and references Includes supporting clinical information putting the mechanisms of disease into perspective
