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This volume explores developments in techniques in diagnostics, DNA sequencing, bioanalysis of immunoassays, and single-molecule detection. It promotes the measurement, identification, monitoring, analysis, and application of near-infrared spectroscopy (NIR) to medical and pharmaceutical advances. The text also considers noninvasive methods of NIR for successful, cost-effective, and prompt diagnoses of diseases.
Discussing strategies to determine the structure and machanisms of numerous compound classics, this book covers new chemical and elctrophoretic techniques for rapid sample preconcentration and separation. It summarizes breakthroughs in the theory and instrumentation of electrospray mass spectrometry in pharmaceutical and biomedical applications, provides practical examples for the characterization of peptides, proteins, and glycoproteins, includes applications in proteomics, combinatorial chemistry, and drug characterization. Topics include chemical and electrophoretic techniques for rapid sample preconcentration and separation, screening processes for proteins from libraries of compounds, protein folding and dynamics, and more.
Remarkable developments in the spectroscopy field regarding ultrashort pulse generation have led to the possibility of producing light pulses ranging from 50 to5 fs and frequency tunable from the near infrared to the ultraviolet range. Such pulses enable us to follow the coupling of vibrational motion to the electronic transitions in molecules and
Whatever your ICP-MS experience, you probably know that there are many textbooks compiled and edited by academics that approach ICP-MS from a purely theoretical and fundamental perspective, but there aren't any books that provide a practical perspective of the technique that are written specifically for the novice user. You'll be glad to know that
Ithasbeenstatedthatourknowledgedoublesevery20years,butthatmaybe an understatement when considering the Life Sciences. A series of discoveries and inventions have propelled our knowledge from the recognition that DNA isthegeneticmaterialtoabasicmolecularunderstandingofourselvesandthe living world around us in less than 50 years. Crucial to this rapid progress was thediscoveryofthedouble-helicalstructureofDNA,whichlaidthefoundation forallhybridizationbasedtechnologies. Thediscoveriesofrestrictionenzymes, ligases, polymerases, combined with key innovations in DNA synthesis and sequencing ushered in the era of biotechnologyas a new science with profound sociological and economic implications tha...
This book summarizes the results of the NATO Advanced Research Workshop on "Syntheses, Optical Properties, and Applications of Near-Infrared (NIR) Dyes in High Technology Fields" held at Trest (Czech Republic) from September 24 to 27, 1997. It was attended by 52 scientists from 16 countries, among them 18 participants from 8 Eastern-Europe. The Workshop has been stimulated by the great progress that has been made in utilizing NIR dyes in high technology areas. This has been triggered by the availability of reliable. vel)' small, and inexpensive laser diodes emitting in the NIR region which raise the analytical detection limits by several orders of magnitude, allow time-resolved measurements for temporal discrimination between spectrally similar species, and make possible miniaturization as well as remote sensing through space and by fiber optical techniques. Furthermore, NIR dyes proved to be vel)' important in other high technology fields such as laser physics, optical recording techniques, nonlinear optics, biochemistty and medicine.
Fast, inexpensive, and easy-to-use, near-infrared (NIR) spectroscopy can be used to analyze small samples of virtually any composition. The Handbook of Near Infrared Analysis, Third Edition explains how to perform accurate as well as time- and cost-effective analyses across a growing spectrum of disciplines. Presenting nearly 50% new and re
"Updates fundamentals and applications of all modes of x-ray spectrometry, including total reflection and polarized beam x-ray fluorescence analysis, and synchrotron radiation induced x-ray emission. Promotes the accurate measurement of samples while reducing the scattered background in the x-ray spectrum."
This work covers principles of Raman theory, analysis, instrumentation, and measurement, specifying up-to-the-minute benefits of Raman spectroscopy in a variety of industrial and academic fields, and how to cultivate growth in new disciplines. It contains case studies that illustrate current techniques in data extraction and analysis, as well as over 500 drawings and photographs that clarify and reinforce critical text material. The authors discuss Raman spectra of gases; Raman spectroscopy applied to crystals, applications to gemology, in vivo Raman spectroscopy, applications in forensic science, and collectivity of vibrational modes, among many other topics.
Since the completion of the first edition of this book, major developments have occurred in the pharmaceutical industry that have shaped the field of near-infrared (NIR) spectroscopy. A new initiative from the U.S. Food and Drug Administration (FDA) to modernize regulations of pharmaceutical manufacturing and drug quality has helped position NIR spectroscopy as an effective tool for pharmaceutical testing. Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy: Second Edition reflects these developments and brings readers an up-to-date summary of how this technique is being applied to pharmaceutical manufacturing. Topics include: The origins and principles of NIR spectroscopy,...