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Radiotherapy in Cancer Care
Cancer treatment is complex and calls for a diverse set of services. Radiation therapy is recognized as an essential tool in the cure and palliation of cancer. Currently, access to radiation treatment is limited in many countries and non-existent in some. This lack of radiation therapy resources exacerbates the burden of disease and underscores the continuing health care disparity among States. Closing this gap represents an essential measure in addressing this global health equity problem. This publication presents a comprehensive overview of the major topics and issues to be taken into consideration when planning a strategy to address this problem, in particular in low and middle income countries. With contributions from leaders in the field, it provides an introduction to the achievements and issues of radiation therapy as a cancer treatment modality around the world. Dedicated chapters focus on the new radiotherapy technologies, proton beams, carbon ion, intraoperative radiotherapy, radiotherapy for children, treatment of HIV-AIDS malignancies, and costing and quality management issues.
Carbohydrate Recognition
This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.
Environmental Aspects of Zoonotic Diseases
Environmental Aspects of Zoonotic Diseases provides a definitive description, commentary and research needs of environmental aspects related to zoonotic diseases. There are many interrelated connections between the environment and zoonotic diseases such as: water, soil, air and agriculture. The book presents investigations of these connections, with specific reference to environmental processes such as: deforestation, floods, draughts, irrigation practices, soil transfer and their impact on bacterial, viral, fungal, and parasitological spread. Environmental aspects such as climate (tropical, sub-tropical, temperate, arid and semi-arid), developed and undeveloped countries, animal (domestic a...
Veterinary Mycology
This book is a comprehensive overview of the fungi that are clinically relevant for animals and humans. It is divided in three major parts: the first part comprises the history of veterinary and medical mycology, general aspects of morphology, growth, nutrition, reproduction and classification of fungi. In the second part, the etiologic agents of cutaneous, subcutaneous and systemic mycoses are described in detail with special emphasis on emerging and uncommon pathogenic fungi. Each chapter consists of a brief history and the morphology, classification, reproduction, susceptibility to disinfectants, natural habitat, distribution, genome, isolation, growth and colony characteristics, antigenic characteristics, virulence factors. The major diseases and their routes of transmission, pathogenesis, immunity, diagnosis and treatment are also covered. The third part focuses on laboratory diagnosis including clinical sample collection, their processing for fungal isolation, special stains for microscopic visualization, culture media composition and a relevant glossary. Each chapter includes color photographs, schematic diagrams and tables for better understanding.
Handbook of HIV and Social Work
Praise for Handbook of HIV and Social Work "Cynthia Cannon Poindexter has given us a remarkable edited volume that contains much information on HIV that every professional social worker needs to know in order to practice competently in today's complex world."—From the Foreword by Vincent J. Lynch, MSW, PhD, Boston College Graduate School of Social Work "This comprehensive handbook assembles a group of social work scholars and practitioners to participate in, guide, and address many of the unresolved challenges characterizing the HIV debates. This handbook is a valuable and timely addition to the literature."—King Davis, MSW, PhD, The Robert Lee Sutherland Chair in Mental Health and Socia...
Handbook of Dual Diagnosis
This handbook addresses behavior problems and mental health disorders in persons with intellectual disabilities. It provides an overview of the history of dual diagnosis and related theories, ethics, diagnostic systems, mental health disorders, and challenging behaviors. The handbook examines general clinical issues, such as the effects of cognitive performance on the choice of assessment and treatment methods, service delivery systems, education models, risk factors, functional assessment, and structured interviews. Chapters provide a much-needed reference for practitioners and practitioners in training. The applied focus of the book continues with assessment/diagnosis sections of mental he...
Molecular Pathogenesis of Colorectal Cancer
Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease.
Lasers, Lights and Other Technologies
The series “Clinical Approach and Procedures in Cosmetic Dermatology” intends to be a practical guide in Cosmetic Dermatology. Procedures in cosmetic dermatology are very popular and useful in medicine, indicated to complement topical and oral treatments not only for photodamaged skin but also for other dermatosis such as acne, rosacea, scars, etc. Also, full-face treatments using peelings, lasers, fillers and toxins are increasingly being used, successfully substituting or postponing the need for plastic surgeries. Altogether, these techniques not only provide immediate results but also help patients to sustain long-term benefits, both preventing/treating dermatological diseases and mai...
Approaching Complex Diseases
This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor eff...
Radiomics and Radiogenomics
Radiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, a...
