Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Interleukin-10
The presented information reflects a state-of-the-art summary of the pleiotropic effects of IL-10 in vitro and in vivo and will contribute to our understanding of the role of ILj-10 in the immune system and its potential clinicial utility in the near future. The book contains chapters in which the in vitro biological effects of IL-10 on both mouse and human lymphoid and myeloid cells are reviewed. In addition, the role of IL-10 in transplantation, parasite infections, inflammation, infectious diseases and bone formation is described. The effects of IL-10 in vivo are presented, describing an IL-10 transgenic mouse model, the IL-10 "knock-out" mouse, and the capacity of IL-10 to prevent lethal toxic shock in mice.
Autoantibodies
None
Signal Transduction and Bacterial Virulence
In order to survive, bacteria must constantly monitor their structure and physiology. Adaptive behaviours are established by using environmental sensors and response regulators. These communication modules regulate a wide variety of signals including host detection and invasion, cell cycle, metabolite utilization, starvation and many others. The purpose of this volume is to give an overview of the various systems and to introduce recent advances in understanding selected systems of pathogenic bacteria.
The Cytokine Handbook
The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Expanded to two volumes, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems.
Spontaneous and Induced Intima Formation in Blood Vessels
Atherosclerosis, the most common disease in humans and also the main cause of death in the Western world, only develops after an intima is formed. The intima is defined as the region of the arterial wall from the endothelial surface to the luminal margin of the media. This volume considers all aspects of intima formation based on results which had been obtained by studying three different models: - Spontaneous intima formation; - Experimentally induced intima formation; - Latrogeneously induced intima formation.
IL-4
The Structure and Function of Interleukin-4 provides a detailed summary of the pleiotrophic effects of IL-4. In Section I, the structure of the IL-4 gene, IL-4R gene, and IL-4 protein are described. In Section II, in vitro effects of IL-4 are reviewed and focus is on particular cell lineage, as well as the role of IL-4 in hemopoiesis. Section III features chapters that discuss the effects of IL-4 in vivo, highlighting the dramatic ability of IL-4 to induce the switch of B cells to produce IgE. The Structure and Function of Interleukin-4 is an important book for immunologists, cell biologists, and pharmacologists who need a succinct description of the role of IL-4 in the development of different cell types and in cell-cell communication in the immune system.
Monoclonal Antibodies in Transplantation
Experimental and clinical evidence presented in this book illustrates that antibodies expressing different specificities can be very effective in preventing or reversing established transplant rejection. Moreover, the data leads us to hope that the use of these new therapeutic agents may allow the induction of specific tolerance to transplant alloantigens which is the only means to avoid the major risks of sustained immunosuppression, namely an increased susceptibility to infection and tumor development. In this volume the editors combine contributions dealing with very practical aspects of the clinical use of monoclonal antibodies with a more general discussion on the developments one may foresee in the near future.
Pre-mRNA Processing
he past fifteen years have seen tremendous growth in our understanding of T the many post-transcriptional processing steps involved in producing func tional eukaryotic mRNA from primary gene transcripts (pre-mRNA). New processing reactions, such as splicing and RNA editing, have been discovered and detailed biochemical and genetic studies continue to yield important new insights into the reaction mechanisms and molecular interactions involved. It is now apparent that regulation of RNA processing plays a significant role in the control of gene expression and development. An increased understanding of RNA processing mechanisms has also proved to be of considerable clinical importance in the pa...
c-Myc Function in Neoplasia
1. 1 SCOPE OF BOOK n explosion of novel findings in the past decade has contrib A uted to the great progress toward understanding the biology of human cancers. Much of this progress can be attributed to our abil ity to dissect many biological processes at the molecular level. Most spectacular is the technology of molecular biology that allows identi fication and characterization of genes that participate in the genesis of human cancers. Three major groups of genes appear to play out the drama of cancer development: tumor suppressor genes, mis match repair genes, and oncogenes. The tumor suppressor genes 1 encode products that are inhibitory to cell proliferation. The loss of these inhibitors...
