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This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics. Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies. The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.
Dutch authors on Asian history presents fifteen essays on Dutch expansion and colonization in Asia before 1800, during the period of the Verenigde Oostindische Compagnie (VOC). This collection offers the opportunity to make acquaintance with the nature and development of colonial historiography as practiced in the Netherlands in the second half of the nineteenth and the first half of the twentieth century. Although Dutch historiography on Asia and the VOC underwent considerable change after 1960, especially as a result of decolonization, the work of these early historians has not lost its importance. For many aspects of the history of Asia and the VOC these studies supply valuable data and l...