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In recent years, micro- and nanosystems with magnetic properties have been extensively investigated in many fields, ranging from physics to medicine. The research in these areas has lately shown that if the magnetic compounds are opportunely functionalized and modified with moieties and specific functional groups, a plethora of challenging multidisciplinary applications is available, including the development of magnetically controlled particles, stimuli-responsive materials, magnetically guided chemical/drug-delivery systems, sensors, spintronics, separation and purification of contaminated groundwater and soils, ferrofluids and magnetorheological fluids, contrast agents for MRI, and intern...
The effects of US secondary sanctions are broad and are often designed to cripple the target country’s economy and currency. Some states have sought to circumvent these sanctions by setting up a special purpose vehicle to facilitate trade and financial transactions with the sanctioned country on humanitarian grounds. Although the nature of these special purpose vehicles is new and experimental, they are little understood, not least how they operate and function in international law. This volume addresses this gap by identifying and examining some of the legal issues that a special purpose vehicle such as the Instrument in Support of Trade Exchanges (INSTEX) generates. The collection brings together leading legal academics, sanctions practitioners and policy experts to provide an assessment of the special purpose vehicle in the context of secondary sanctions in international law. It will be of interest to researchers and academics in International law, Security law, Economic law and Comparative law.
This open access book evaluates research quality, quality of teaching and the relationship between the two through sound statistical methods, and in a comparative perspective with other European countries. In so doing, it covers an increasingly important topic for universities that affects university funding. It discusses whether university evaluation should be limited to a single factor or consider multiple dimensions of research, since academic careers, teaching and awarding degrees are intertwined. The chapters included in the book evaluate teaching and research, also taking the gender dimension into account, in order to understand where and when gender discrimination occurs in assessment...
This book is a printed edition of the Special Issue "The Identification of the Genetic Components of Autism Spectrum Disorders 2017" that was published in IJMS
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder characterized by progressive cognitive dysfunction and memory loss, inability to perform the activities of daily living and mood disorders. According to the so-called “amyloid cascade hypothesis”, amyloid-ß- peptide (Aß), produced by beta- and gamma- secretase-mediated cleavages of the amyloid precursor protein (APP), plays a pivotal role in the pathogenesis of AD. Aß was also shown to contribute to AD pathology by stimulating the hyperphosphorylation of tau which is responsible for the formation of neurofibrillary tangles. However, the “amyloid cascade hypothesis” was challenged by other theories which lend suppor...
Recent research on Neurodegenerative disorders such as Alzheimer's Disease, Parkinson's Disease, etc. and Neuropsychiatric disorders such as Schizophrenia, has shown strong evidence that altered brain tissue structure, physiology, and connectivity reflect the extent of severity of behavioral and physical abnormalities. With the advancement of high field strength MR technologies like MRS (Magnetic Resonance Spectroscopy), fMRI (functional Magnetic Resonance Imaging) and DTI (Diffusion Tensor Imaging), it has become possible to non-invasively measure these changes brain microenvironment in terms of levels of antioxidants; neurotransmitters; regional activity, susceptibility and connectivity du...
This book is a printed edition of the Special Issue Novel Photoactive Materials that was published in Materials
Multilateral organizations - the United Nations (UN) in particular - have played, and continue to play, an important role in shaping the security sector reform (SSR) agenda, both in terms of policy development and the provision of support to a wide range of national SSR processes. This volume presents a variety of perspectives on UN support to SSR, past and present, with attention to policy and operational practice. Drawing from the experience of UN practitioners combined with external experts on SSR, this volume offers an in-depth exploration of the UN approach to SSR from a global perspective.
The defense industry develops, produces, and sells weapons that cause great harm. It operates at the intersection of the public and private sectors, with increased reliance on technology companies. Although such firms exist primarily to serve their host states, they routinely interact with foreign legal systems and diverse cultures. This context creates unique ethical challenges. That being the case, is the defense industry ethically defensible? How should it be regulated? How should it respond to worrisome technological developments such as autonomous weapons systems? How should business be conducted in countries where bribery is the norm? To what extent can this industry's intrinsic ethical problems be overcome? This book addresses such questions, bringing together the diverse perspectives of scholars and practitioners from academia, government service, the military, and the private sector. It aims to inform a discussion about the moral and legal challenges facing the global defense industry and to introduce solutions that are innovative, effective, and practical.