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Parkinson Disease
"Description and discussion of the many aspects of Parkinson disease (PD) is dogged by the fact that PD is an ambiguous concept. What we call PD is an etiologically and clinically heterogeneous meta-syndrome overlapping a number of other disorders. Definitions, diagnostic criteria, and classification schema provide essential common vocabularies for communication among clinicians and researchers. Definitions, diagnostic criteria, and classification schemes for PD, however, are constructs imposed on variable and imperfectly understood disease biology. Difficulties with formulation of PD definitions, diagnostic criteria, and classification schemes include historical and contemporary use of competing definitions of PD, disease heterogeneity, the existence of disorders with overlapping clinical and pathological features, and ambiguous use of the terms disease and syndrome. For the purposes of exposition and discussion in this book, an inclusive, perhaps vague, definition of PD is employed:"
Cognition in Parkinson's Disease
Cognition in Parkinson's Disease, Volume 269 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Cognition in Prodromal Parkinson's disease, The epidemiology of cognitive function in Parkinson's disease, Real-life consequences of cognitive dysfunction in Parkinson's disease, Animal models of cognition in Parkinson's disease, Functional neuroanatomy of cognition in Parkinson's disease, Neuroimaging approaches to cognition in Parkinson's disease, Cognitive dysfunction and neuropsychiatric aspects of Parkinson's disease, Neuropsychology of Parkinson's disease, Cholinergic Systems, Attentional-Motor Integration, and Cognitive Control in Parkinson Disease, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Progress in Brain Research series - Updated release includes the latest information on Cognition in Parkinson's Disease
D.R.D.A. Reporter
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Neurologic Complications of Critical Illness
Neurologic consultations are essential to patient outcomes, not only providing diagnostic, therapeutic, and prognostic advice but also directing care to the patient. Neurologic Complications of Critical Illness is the foremost guide for neurologists entering the intensive care unit (ICU). This fourth edition has been thoroughly updated, refreshed, and expanded in recognition of the vast number of changes in neurology and neurocritical care. In addition, every chapter provides a representative selection of the state-of-the art management and latest clinical innovations in critical care medicine. As with previous editions, the book offers practical advice on dealing with coma and outcome after...
Tourette Syndrome
This volume provides a summary review of all recently published and ongoing research initiatives related to Tourette Syndrome. The latest research is presented in a clinical context, and controversial issues are fully discussed using an evidence-based approach. These issues include the prevalence of TS, the nature of the TS phenotype, the role of autoimmunity in the development of TS, the role of comorbidity in functional outcomes of TS patients, and approaches to identifying the TS gene/genes. Chapters describe recent advances in neuroimaging, genetics, and treatment. The book includes extensive discussions of co-morbid disorders: obsessive-compulsive disorder, attention deficit hyperactivity disorder, mood disorders, and tics.
Emergency Neurology
A comprehensive clinical reference in emergency neurology, from prehospital care to the final disposition of the patient.
Neurobiology of Huntington's Disease
In 1993, the genetic mutation responsible for Huntington's disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse range of biochemical and genetic perturbations that see
Mapping Fate
Wexler tells the story of a family at risk for Huntington's disease, a hereditary, incurable, fatal disorder from which her own mother died. This graceful and eloquent account goes beyond the specifics of the disease to explore the dynamics of family secrets, of living at risk, and the drama and limits of biomedical research. Photos.
A Life Shaken
"I'm flat on my back on a couch that's too short in a windowless room in the bureau. I can't even sit at a computer, much less make a keyboard work. My arms and legs are shaking uncontrollably. Although I am only 53 years old, I have already been struggling with Parkinson's disease for seven years. And right now the disease is winning." So begins Joel Havemann's account of the insidious disease that is Parkinson's. Into his own story, Havemann weaves accessible explanations of how Parkinson's disrupts the brain's circuitry, how symptoms are managed through drugs and surgery, and how people cope with the disease's psychological challenges. The updated paperback edition brings the discussion of treatment options and research thoroughly up to date.
