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The need for neuropathology reviews in epilepsy surgery tissues steadily increases. However, textbooks and case presentations highlighting and focusing on this specific topic are rare. The authors of this book reviewed their professional experience in surgical and post-mortem neuropathology studies to compile a coherent summary of: clinico-pathological findings, current classification schemes, useful protocols research data for major histopathological entities of brain lesions encountered in modern epilepsy surgery programs, which is hippocampal sclerosis, brain tumours associated with early epilepsy onset, malformations of cortical development, brain inflammation and malformative vascular lesions. They did not intend to be exhaustive but rather representative of the main lesions and pathologies encountered. Thirty-two illustrated cases constitute the core of this book and will be very helpful in current practice.
This book critically appraises the role and value of specific diagnostic and treatment techniques for drug-resistant, MRI-negative epilepsy. The authors present the evidence and share their expertise on the diagnostic options and surgical approaches that make epilepsy surgery possible and worthwhile in this complex and challenging condition.
Epilepsy is the most common serious neurological condition, affecting children and adults, and can occur in a variety of medical settings. It has many causes and many forms, and a variable prognosis. Mortality and morbidity are high, social and legal consequences can stretch well beyond the purely medical, and its management is often poor. Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures. Written by internationally-renowned specialists, each chapter comprehensively covers the current knowledge and evidence base related to each aspect of the disorder, with an emphasis...
Authoritative and updated, Epilepsy: A Comprehensive Textbook, 3rd Edition, contains 365 chapters that cover the full spectrum of relevant topics in biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Written by world-renowned authorities and expertly edited by epileptologists Drs. Jerome Engel, Jr., Solomon L. Moshé, Aristea S. Galanopoulou, John M. Stern, Alexis Arzimanoglou, Jacqueline A. French, Renzo Guerrini, Andres M. Kanner, and Istvan Mody, this three-volume work includes detailed discussions of seizure types and epilepsy syndromes, relationships between physiology and clinical events, psychiatric and medical comorbidities, conditions that could be mistaken for epilepsy, and an increasing range of pharmacologic, surgical, and alternative therapies.
A panoramic view of the evolution of life on our planet, from its origins to humanity’s future. In A History of Bodies, Brains, and Minds, Francisco Aboitiz provides a brief history of life, the brain, and cognition, from the earliest living beings to our own species. The author proceeds from the basic premise that, since evolution by natural selection is the process underlying the origin of life and its evolution on earth, the brain—and thus our minds—must also be the result of biological evolution. The aim of this book is to narrate how animal bodies came to be built with their nervous systems and how our species evolved with culture, technology, language, and consciousness. The book...
Since 1984, the year of the publication of its first edition, the famous “Blue Guide” has been the international reference for paediatricians and neuropaediatricians with regard to epileptic syndromes in infants, children and adolescents. This 6th edition reviews some of the most noteworthy developments in the field, particularly in epileptic syndromes, but also focuses on the genetic aspects of the syndromes and their development. Progress brought about by advances in neuroimaging is also discussed in addition to specific etiologies such as parasitic diseases and immune and autoimmune diseases. The different backgrounds of the contributors - coordinators and authors – ensure that the book’s longstanding reputation for objectivity and seriousness, built over almost 35 years, remain well-deserved. This book written by the current leading specialists is recognized worldwide as the international reference in epilepsy.
Neuropathology, Volume 145, the latest release in the Handbook of Clinical Neurology series, includes all the major topics found in a typical neuropathology text, but differentiates itself by providing a thorough overview of the morphological background of neurological disorders for researchers and clinicians who do not specialize in pathology or its clinicopathological aspects. This volume offers strong coverage of brain imaging and advances in molecular pathology and genetics, and is particularly timely given the amount of neuropathological research currently taking place. - Provides a resource for the non-pathologist, aiding primary clinicians and researchers in the interpretation of patient symptoms and research findings - Includes standard neuropathology, but extends to clinicopathology, imaging and molecular pathology/genetics - Presents an interdisciplinary approach that can be applied in everyday clinic and research efforts
Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. - Provides a comprehensive reference detailing animal models of epilepsy and seizure - Offers insights on the use of novel technologies that can be applied in experimental epilepsy research - Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques - Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments