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Neuronal and Glial Structural Plasticity Induced by Drugs of Abuse
Drugs of abuse induce a host of alterations in brain structure and function, ranging from changes in gene expression and epigenetic processes to aberrant synaptic plasticity to volumetric changes in discrete brain regions. These alterations can be drug class-specific, and are not confined to neurons, as drugs of abuse also induce molecular and cellular alterations in various glial cell types such as astrocytes and microglia. The phenomenon of drug-induced plasticity includes changes in dendritic branching and architecture, dendritic spine density and morphology, astrocyte-neuronal interactions, dysregulation of glutamatergic and GABAergic signaling, and alterations in myelination or microglial phenotype. This drug-induced "rewiring" of the brain at numerous levels can contribute to the development, maintenance, and persistence of the addicted state, as well as associated deficits in normal cognitive functioning. The aim of this Research Topic is to collect recent and important findings related to the structural alterations produced by drug of abuse in neurons, glial, and other cell types of the central nervous system.
Interactive Probiotics
This book underlines the importance of reciprocal interactions between probiotics and humans in terms of stress induction, epigenetic control of cellular responses, oxidative status, bioactive molecules biosynthesis, moonlighting proteins secretion, endogenous toxins neutralization, and several other biological functions. It explores how these responses can affect metabolism and metabolic-related disorders, gutbrain axis balance, mood, inflammatory, allergic and anti-infective reactions, cancer, and ageing. The book explores how probiotics create a dynamic and "fluid" network of signals able to control the balance between healthy and altered human status.
Neuronal Nicotinic Receptors
Neuronal nicotinic receptors are key molecules for signal transduction in a number of neuronal pathways. They are widely distributed in the brain and are known to be involved in cognitive tasks, including learning and memory, in smoking addiction and in several brain diseases, such as Alzheimer's and Parkinson's dementias, schizophrenia, and epilepsy. This book provides a comprehensive review of the field, starting with a historical perspective and dealing with the molecular structure of these receptors, their biophysical and pharmacological properties, their distribution in central and peripheral nervous systems, and their major involvement in brain functions. Particular emphasis is paid to drugs (both new and old) that are useful in the diagnosis and treatment of diseases involving neuronal nicotinic receptors. Finally, the relevance of these receptors in smoking addiction is carefully evaluated, together with future trends and the latest results.
Postoperative Critical Care for Cardiac Surgical Patients
Cardiac surgical procedures are among the most common and most complicated forms of surgery worldwide and the postoperative period is characterized by complex challenges. Among the factors determining ultimate clinical outcome, postoperative critical care is of major importance. This book adopts a clinical approach in explaining and analyzing the course of clinical care in patients undergoing cardiac surgery. Since the postoperative clinical status is directly influenced by preoperative and intraoperative factors, the early chapters briefly examine preoperative issues and the intraoperative course of cardiac surgery, with particular attention to anesthesia and the process of cardiopulmonary bypass. Subsequent chapters primarily address the critical care of patients by means of an organ-oriented approach, which will enable the reader to use the text as a "cookbook" of cardiac intensive care. This book is intended for use in daily practice by cardiac surgeons, cardiac anesthesiologists, intensivists and cardiac intensive care nurses.
Nursing Theorists and Their Work
The most comprehensive of its kind, Nursing Theorists and Their Work, 8th Edition provides an in-depth look at 39 theorists of historical, international, and significant importance. Each chapter features a clear, consistent presentation of a key nursing philosophy or theory. Case studies, critical thinking activities, and in-depth objective critiques of nursing theories help bridge the gap between theory and application. Critical Thinking Activities at the end of each theorist chapter help you to process the theory presented and apply it to personal and hypothetical practice situations.A case study at the end of each theorist chapter puts the theory into a larger perspective, demonstrating h...
3D, 4D and Predictive Modelling of Major Mineral Belts in Europe
This book presents the results of the major EU project Promine. For the first time there is now a European database available on mineral deposits, as well as 3D, 4D and predictive models of major mineral belts in Europe: Fennoscandia (Skellefteå and Vihanti-Pyhäsalmi), the Fore-Sudetic basin (Kupferschiefer deposits in Poland and Germany), the Hellenic belt in northern Greece, and the Iberian Pyrite belt and Ossa Morena zone in Spain and Portugal. The book also describes the modelling techniques applied and how different types of software are used for three- and four-dimensional modelling. Furthermore, fundamental descriptions of how to build the database structure of three-dimensional geological data are provided and both 2D and 3D predictive models are presented for the main mineral belts of Europe.
Nursing Theorists and Their Work E-Book
**Selected for Doody's Core Titles® 2024 with "Essential Purchase" designation in Theory** Find the thinking of 39 leading nursing theorists in one comprehensive text! Nursing Theorists and Their Work, 10th Edition provides a clear, in-depth look at nursing theories of historical and international significance. Each chapter presents a key nursing theory or philosophy, showing how systematic theoretical evidence can enhance decision making, professionalism, and quality of care. Lead author Martha Raile Alligood is known nationally and internationally for her expertise in nursing theory. A classic in the field of nursing theory, this text uses objective critiques, case studies, and critical t...
Precambrian Geology of Finland
Focusing on the Precambrian in the central part of the Fennoscandian Shield, the book combines the results from modern geological and geophysical research into a detailed petrologic, lithologic, and structural synthesis and interpretation of the Archean and Proterozoic of Finland. It will be of value to anyone interested in the evolution of the shield in particular and in Precambrian geology in general.
Lymphedema
This volume is a clinically-oriented book that can be used for patient care, teaching, or research. It covers the entire field of lymphedema, including both primary and secondary disease, as well as all diagnostic and treatment modalities. The text begins with a foundation for the condition, including its pathophysiology, epidemiology, and morbidity. Next, the classification of lymphedema is covered which is the template for accurate diagnosis. Clinical, radiological, and differential diagnosis of lymphedema is also reviewed. Finally, conservative and operative management is presented, including both physiologic and excisional procedures. Lymphedema: Presentation, Diagnosis, and Treatment pr...
