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Chemical Warfare Toxicology
This book provides an up-to-date treatise on the on-going research into the toxicology of chemical warfare agents, the diagnosis and verification of exposure, and the pre- and post-exposure treatment of poisoning.
The Neurobiology and Genetics of Nicotine and Tobacco
The primary purpose of this book and its companion volume The Neuropharmacology of Nicotine Dependence is to explore the ways in which recent studies on nicotine and its role in tobacco addiction have opened our eyes to the psychopharmacological properties of this unique and fascinating drug. While the present volume considers the molecular and genetic factors which influence behavioral responses to nicotine and how these may impact on the role of nicotine in tobacco dependence, the book The Neuropharmacology of Nicotine Dependence focuses on the complex neural and psychological mechanisms that mediate nicotine dependence in experimental animal models and their relationship to tobacco addiction in humans. These volumes will provide readers with a contemporary overview of current research on nicotine psychopharmacology and its role in tobacco dependence from leaders in this field of research and will hopefully prove valuable to those who are developing their own research programmes in this important topic.
Neuronal Nicotinic Receptors
Neuronal nicotinic receptors are key molecules for signal transduction in a number of neuronal pathways. They are widely distributed in the brain and are known to be involved in cognitive tasks, including learning and memory, in smoking addiction and in several brain diseases, such as Alzheimer's and Parkinson's dementias, schizophrenia, and epilepsy. This book provides a comprehensive review of the field, starting with a historical perspective and dealing with the molecular structure of these receptors, their biophysical and pharmacological properties, their distribution in central and peripheral nervous systems, and their major involvement in brain functions. Particular emphasis is paid to drugs (both new and old) that are useful in the diagnosis and treatment of diseases involving neuronal nicotinic receptors. Finally, the relevance of these receptors in smoking addiction is carefully evaluated, together with future trends and the latest results.
Plastic Scintillators
This book introduces the physics and chemistry of plastic scintillators (fluorescent polymers) that are able to emit light when exposed to ionizing radiation, discussing their chemical modification in the early 1950s and 1960s, as well as the renewed upsurge in interest in the 21st century. The book presents contributions from various researchers on broad aspects of plastic scintillators, from physics, chemistry, materials science and applications, covering topics such as the chemical nature of the polymer and/or the fluorophores, modification of the photophysical properties (decay time, emission wavelength) and loading of additives to make the material more sensitive to, e.g., fast neutrons, thermal neutrons or gamma rays. It also describes the benefits of recent technological advances for plastic scintillators, such as nanomaterials and quantum dots, which allow features that were previously not achievable with regular organic molecules or organometallics.
Atlas of Bone Marrow Pathology
This text illustrates bone marrow aspirate, imprint and biopsy specimens showing characteristic features of a wide variety of neoplastic and non-neoplastic conditions. While the focus is on Wright-stained smears and hematoxylin-eosin stained biopsies, other key histochemical and immunohistochemical stains are illustrated that are vital for proper diagnosis. After a brief review of the normal bone marrow, reactive changes in the marrow are illustrated, including the bone marrow response in constitutional disorders and to metabolic changes throughout the body. This is followed by specific infectious disorders in the marrow and other non-neoplastic disorders. The remainder of the Atlas illustrates the various neoplasms that involve the bone marrow, including leukemias, lymphomas and non-hematopoietic neoplasms. The hematologic neoplasms are classified using the 2016 World Health Organization (WHO) classification. This overview of bone marrow disorders illustrates a wide variety of diseases that practicing pathologists and hematologists will encounter in their routine practice.
Complex Criminal Litigation: Prosecuting Drug Enterprises and Organized Crime - Third Edition
Complex Criminal Litigation: Prosecuting Drug Enterprises and Organized Crime provides practitioners and others interested in the federal criminal justice system with a comprehensive analysis of the arsenal of federal laws that provide federal prosecutors the means to combat criminal organizations, their leadership (i.e. the so-called "kingpins") and their infrastructure. These statutes include the Racketeer Influenced and Corrupt Organizations Act (RICO); the Continuing Criminal Enterprise or CCE statute; the Money Laundering Control Act; federal firearms statutes; and criminal and civil forfeiture laws that permit the seizure and forfeiture of the profits and instrumentalities of illegal e...
Federal Money Laundering Regulation
Federal Money Laundering Regulation: Banking, Corporate and Securities Compliance is a comprehensive guide to understanding and complying with all U.S. legislation and regulatory requirements governing money laundering. Carefully written and well-organized, this book is the most authoritative but practical publication available in this subject area. Users of the book include banks, credit unions, securities broker-dealers, casinos, money services businesses, futures commission merchants, mutual funds, insurance companies and other financial institutions and their legal counsel, As well as regulatory and law enforcement agencies, The criminal bar, public accountants, and federal and state courts. The easy-to-use looseleaf format allows the reader to keep the volume up to date as annual supplements are issued. The current volume has approximately 1100 pages, organized in 27 chapters. Read the highlights in the latest supplement for Federal Money Laundering Regulation: Banking, Corporate and Securities Compliance .
Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications
The exploration of the subnuclear world is done through increasingly complex experiments covering a wide range of energy and performed in a large variety of environments from particle accelerators, underground detectors to satellites and space laboratory. The achievement of these research programs calls for novel techniques, new materials and instrumentation to be used in detectors, often of large scale. Therefore, fundamental physics is at the forefront of technological advance and also leads to many applications. Among these, medical applications have a particular importance due to health and social benefits they bring to the public.
Ion Transport
Ion Transport is a collection of papers from the Smith Kline & French Research "Symposium on Ion Transport" held in Cambridge, on April 12-14, 1989. These papers focus on the plasma membrane, particularly on the three main classes of transporters, namely, pumps, exchangers, and channels. Some papers discuss the different experimental approaches from electrophysiological and ion flux measurements through pharmacology, molecular biology, electrostatics, and computer modeling. Other papers discuss the P-type cation pump, a class of ATP-driven ion pumps, which is determined from its subunit composition and from the results of the hydrolysis of ATP. Several papers explain the techniques used in i...
Neurotox ’91
NEUROTOX '91 was the fourth meeting in a series which started in 1979. The '91 meeting, like its predecessors, was held under the patronage of the Society of Chemical Industry, and despite the unfortunate proximity of hostilities in the Arabian Gulf attracted a truly international mix of industrial and academic pesticide scientists. This volume contains the text of invited papers read at the meeting and presents the dramatic developments which so excited those who attended. The potential of molecular neurobiology for gaining knowledge of target sites for neurotoxicants is now starting to be realised. These studies, in conjunction with developments in molecular imaging and modelling, provide ...
